HPLC Columns and Cartridges

Pre-packed columns, cartridges, guard columns, and guard column accessories designed for use with HPLC/UHPLC systems and methods. Products are available with a variety of stationary phases, particle sizes, and column dimensions to meet specific separation needs.
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Acclaim™ 120 C18 Columns Thermo Scientific™
Improve the separation efficiency in your reversed-phase applications with Thermo Scientific™ Acclaim™ 120 C18 columns. These columns feature an ultrapure silica substrate with extremely low metal content to minimize tailing effects and deliver symmetrical peak shapes.
Hypersil™ BDS C18 Columns Thermo Scientific™
For a robust, general-purpose column to use in a wide range of applications, choose Thermo Scientific™ Hypersil™ BDS C18 HPLC Columns. These economical columns feature reduced silanol activity and provide exceptional reliability for QA/QC labs.
Retain and resolve polar analytes using Thermo Scientific™ Hypersil GOLD™ aQ Polar Endcapped C18 columns. These columns provide excellent peak shape, even with challenging reversed phase separations using highly aqueous mobile phases.
Efficiently separate smaller proteins, peptides, anionic species and polar molecules with Thermo Scientific™ Hypersil GOLD™ AX LC Columns. The weak anion-exchange phase, created by a polymeric amine ligand bonded to highly pure base-deactivated silica, separates multiple charged analytes.
Hypersil™ ODS C18 Columns Thermo Scientific™
Choose Thermo Scientific™ Hypersil™ ODS C18 HPLC Columns for a general purpose C18 phase to use in a broad range of applications. Hypersil stationary phases are recognized as an industry standard in HPLC.
Ensure consistent, predictable separations of polar and hydrophilic analytes with Thermo Scientific™ Syncronis™ HILIC LC Columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and deliver reproducible high-resolution separations.
Use the Thermo Scientific™ Acclaim™ Carbonyl C18 LC Columns for superior resolution and high-throughput separation of dinitrophenylhydrazine (DNPH) derivatives of aldehydes and ketones. This silica-based, reversed-phase column provides ideal selectivity and baseline resolution of DNPH derivatives...
Syncronis™ C18 Columns Thermo Scientific™
Achieve repeatable and consistent liquid chromatography (LC) separations using Thermo Scientific™ Syncronis™ C18 columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and ensure robust, high-resolution separations.
Get a high-performance, reversed-phase columns for aminoglycoside analysis. The robust and rugged Thermo Scientific™ Acclaim™ AmG C18 HPLC column provides exceptional tolerance required for aminoglycosides ion-pairing chromatographic separations.
For fast, high-resolution LC/MS separations in bottom-up protein identification, biomarker discovery, and systems biology applications, use Thermo Scientific™ PepSwift™ Monolithic Capillary LC Columns.
Offer 100% porous graphitic carbon for extended separation capabilities with Thermo Scientific™ Hypercarb™ Porous Graphitic Carbon LC Columns. Enhanced retention of polar compounds and separation of structurally related analytes with stability at pH extremes and high temperature.
BioBasic™ 4 HPLC Columns Thermo Scientific™
Designed for the analysis of larger proteins and peptides, Thermo Scientific™ BioBasic™ 4 LC Columns are high-performance columns ideal for the analysis of proteins, peptides and other biomolecules with high hydrophobicity.
Provide outstanding size separation of water soluble compounds with Thermo Scientific™ BioBasic™ SEC 120 Size Exclusion Chromatography preparative HPLC Columns. BioBasic SEC columns provide high efficiency separations for a wide range of molecular weights from 700 to 120,000 daltons, allowing for...
Retain highly polar and hydrophilic analytes, which are difficult to analyze with conventional C18 columns, using Thermo Scientific™ Hypersil GOLD™ PEI HILIC (hydrophilic interaction liquid chromatography) LC Columns.
Use the Thermo Scientific™ Accucore™ Polar Selectivity Kits to verify optimum selectivity of Accucore HPLC columns for polar analytes. Based on Core Enhanced Technology, Accucore columns provide fast, high-resolution separations—without the elevated backpressures required by sub-2μm particles.
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HPLC guard columns are short columns or cartridges that, when installed before an analytical or preparative (U)HPLC column, act as a filter to prevent particulates from entering the main column and trap any chemical contaminants with a high affinity for the stationary phase.
With preparative columns, one size does not fit all. Whether you need unique chemistries for difficult separations to purify your compound of interest, robust columns for longer use, or budget-friendly solutions for routine applications, our preparative HPLC column portfolio has something to meet...
Documents & Support (47)
Specification Sheet: Acclaim PolarAdvantage HPLC Columns: For Operation at Wider Chromatographic Conditions
Application Note: Determination of Gestodene in Human Plasma by SLE-LC-MS/MS Using a Solid Core HPLC Column