September 2020 New Products

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CaptureSelect™ FcXP EvolveD™ Column Thermo Scientific™

CaptureSelect FcXP EvolveD columns are ready-to-use columns designed specifically for use in biopharmaceutical applications. These pre-packed columns are suitable for cGMP manufacturing and have the following features:
• Prepared and packed in a classified ISO7 environment
• An entirely non-metallic flow path
• Qualified in terms of performance and pressure flow characteristics
• Suitable for direct connection to standard chromatography systems
• Available Regulatory Support File
• Packed with CaptureSelect FcXP Affinity Matrix, offering high dynamic binding capacity and high resolution over a wide range of flow rates

Please note that CaptureSelect EvolveD affinity columns are made to order. They are custom manufactured two-at-a-time, so are offered only in quantities that are a multiple of two. For detailed information on the resin, please see the CaptureSelect EvolveD column manual below.

Operating and technical specifications
Column type10-cm bed height20-cm bed height
Column diameter (cm)7102071020
Column length (cm)101010202020
Cross-sectional area (cm2)38.578.5314.238.578.5314.2
Column volume (mL)385785314277015706284

• Pressure rating (bar/psi): 4/58
• Operating temperature: 2–30°C, dependent on the resin packed
• Bed support size: 8 µm
• Inlet/outlet internal diameter: 3 mm or 6 mm depending on the column diameter
• Inlet/outlet port connections: 25-mm TC sanitary fitting

View our comprehensive column overview › (Select the Antibody Purification tab.)

CaptureSelect FcXP Affinity Matrix can be utilized for the purification of IgG and Fc fusion proteins directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in one step.

Features of this affinity matrix include:
• Mild elution, making it suitable for Fc fusion proteins
• Human specific, no binding to bovine antibodies
• Excellent scalability
• Non-animal derived

View other biosimilars and recombinant proteins affinity matrices ›

Free of animal components
CaptureSelect products are affinity ligands created with proprietary technology based on camelid-derived single-domain antibody fragments. The FcXP ligand is a 13-kDa fragment comprising the three complementarity determining regions (CDRs) that form the antigen binding domain. The ligand is efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.

Main characteristics:

Matrix: agarose-based, epoxide-activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect FcXP affinity ligand
Ligand coupling method: epoxide coupling
Binding capacity: 40–50 g IgG/L resin depending on flow rate, column height, and contact time
Elution conditions: 20 mM citric acid or acetic acid, pH 3–4
Max. operation pressure: 2 bar
Formulation buffer: 20% (v/v) ethanol

Gas Mass Flow Controller (MFC) for GXCore Bioprocess Controller, 0–1 SLPM stainless steel flow path Thermo Scientific™

The Thermo Scientific Gas Mass Flow Controller (MFC) for the GXCore Bioprocess Controller is a compact assembly providing four mass flow controllers and two associated solenoid valves in a stainless steel flow path for gas sparge and overlay. When connected, this MFC is instantly recognized by TruBio software to provide precise control of gas flow for pH and/or dissolved oxygen control.

VeritiPro™ Thermal Cycler + Extended Warranty Package, 96 well, ABRC Applied Biosystems™

The Applied Biosystems VeritiPro Thermal Cycler delivers proven reliability with advanced temperature control technology and connectivity. Take advantage of next-level PCR optimization with the precision offered by VeriFlex block technology. Connect to the cloud-enabled VeritiPro Thermal Cycler remotely. Conveniently design and securely upload your methods, monitor runs, and check instrument availability from any mobile device or desktop computer using Connect, our cloud-based platform.

Features of the VeritiPro Thermal Cycler include:
Temperature optimization through VeriFlex technology: VeriFlex blocks are controlled by multiple Peltier elements and are used to optimize PCR temperature with precision. The VeritiPro Thermal Cycler allows for six zones of independent temperature control, giving you the ultimate control of your PCR workflows.
Remote capabilities: By connecting your VeritiPro Thermal Cycler to Connect, you will have complete control of your instrument while away from the lab. With Connect you can check instrument availability through the mobile app, download experimental report files, receive alerts, and more. Download our Instrument Connect App updated with this functionality and visit Connect to design and securely upload your methods from any mobile device or desktop computer.
Simulation mode: The VeritiPro Thermal Cycler is equipped with simulation modes, allowing it to be run using the same ramp rates as previous or different instruments. Through this feature you will be able to mimic the ramp rates of the Veriti, Applied Biosystems 2720, Bio-Rad T100, Bio-Rad MyCycler, Bioer XP Cycler, Eppendorf Mastercycler, MJ Research PTC-200, and Takara Dice PCR thermal cyclers.
Our quietest instrument yet: With all the equipment running in the lab, why should your thermal cycler add to the noise level? We have revised the internal instrument technology to provide your lab with a thermal cycler that runs at a noise level of less than 48 dB(A).
8-inch touch-screen control: The improved, intuitive, and responsive touch-screen interface allows you to program with ease and limits the amount of time spent training new users.
Compact footprint: With the increasing popularity of our smaller instruments, we have updated our trusted Veriti Thermal Cycler with a smaller footprint. The VeritiPro Thermal Cycler can fit on just about any workbench with its dimensions of 24.5 cm wide and 46.7 cm deep.

Learn more about the VeritiPro Thermal Cycler ›

Applied Biosystems PCR plastics
Applied Biosystems PCR plastics have been designed and validated to work with our thermal cyclers for more than 25 years. Options for every format and throughput need are available to ensure consistent, precise results for any experiment. To find the best match, please visit our Plastics Selection Guide.

AB Repair Center (ABRC) extended warranty
In most countries, your thermal cycler comes with a standard two-year warranty. The package offered here provides additional warranty coverage to your existing manufacturer’s limited warranty. With ABRC support, factory-trained engineers will perform maintenance or repair your instrument at our remote service center. Just send us your instrument and we will maintain or repair it and ship it back to you typically within three weeks. All parts, labor, and shipping charges are included.

The ABRC extended warranty is ideal for customers in regulated environments who must maintain asset tag consistency to comply with regulated protocols.

Certain exclusions apply. Contact your Service and Support Representative for details at service.sales@thermofisher.com.

CaptureSelect™ FcXP Affinity Matrix Thermo Scientific™

CaptureSelect FcXP Affinity Matrix is the next-generation CaptureSelect FcXL matrix, specifically designed for higher binding capacity. The selectivity remains identical; the ligand recognizes the CH3 domain of all human IgG subclasses (IgG1, 2, 3, and 4), while maintaining the elution characteristics of CaptureSelect FcXL Affinity Matrix, but the binding capacity is increased (>40 g IgG/L).

Features of this affinity matrix include:
• Mild elution, making it suitable for Fc fusion proteins
• Human-specific, no binding to bovine antibodies
• Excellent scalability
• Non-animal derived

CaptureSelect FcXP Affinity Matrix can be used for the purification of IgG and Fc fusion proteins directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in one step.

View other research scale antibody affinity resins ›

Free of animal components
Our CaptureSelect products are affinity ligands created by a proprietary technology based on camelid-derived single domain antibody fragments. The ligand is a 13-kDa single-domain fragment comprising the three complementarity determining regions (CDRs) that form the antigen-binding domain, efficiently produced in Saccharomyces cerevisiae in a production process free of animal components.

Main characteristics:

Matrix: agarose-based, epoxide activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect FcXP affinity ligand
Ligand coupling method: epoxide coupling
Binding capacity: 40–50 g IgG/L resin depending on flow rate, column height, and contact time
Elution conditions: 20 mM citric acid or acetic acid, pH 3–4, or 100 mM Tris, 2.0 M MgCl2, 40% (v/v) propylene glycol, pH 7
Flow characteristics: 150–300 cm/h (up to 2 bar)
Formulation buffer: 20% (v/v) ethanol

VeritiPro™ Thermal Cycler + Extended Warranty + Plastics Package, 96 well, REX, TriFlex Plates Applied Biosystems™

The Applied Biosystems VeritiPro Thermal Cycler delivers proven reliability with advanced temperature control technology and connectivity. Take advantage of next-level PCR optimization with the precision offered by VeriFlex block technology. Connect to the cloud-enabled VeritiPro Thermal Cycler remotely. Conveniently design and securely upload your methods, monitor runs, and check instrument availability from any mobile device or desktop computer using Connect, our cloud-based platform.

Features of the VeritiPro Thermal Cycler include:
Temperature optimization through VeriFlex technology: VeriFlex blocks are controlled by multiple Peltier elements and are used to optimize PCR temperature with precision. The VeritiPro Thermal Cycler allows for six zones of independent temperature control, giving you the ultimate control of your PCR workflows.
Remote capabilities: By connecting your VeritiPro Thermal Cycler to Connect, you will have complete control of your instrument while away from the lab. With Connect you can check instrument availability through the mobile app, download experimental report files, receive alerts, and more. Download our Instrument Connect App updated with this functionality and visit Connect, our cloud-based platform, to design and securely upload your methods from any mobile device or desktop computer.
Simulation mode: The VeritiPro Thermal Cycler is equipped with simulation modes, allowing it to be run using the same ramp rates as previous or different instruments. Through this feature you will be able to mimic the ramp rates of the Veriti, Applied Biosystems 2720, Bio-Rad T100, Bio-Rad MyCycler, Bioer XP Cycler, Eppendorf Mastercycler, MJ Research PTC-200, and Takara Dice PCR thermal cyclers.
Our quietest instrument yet: With all the equipment running in the lab, why should your thermal cycler add to the noise level? We have revised the internal instrument technology to provide your lab with a thermal cycler that runs at a noise level of less than 48 dB(A).
8-inch touch-screen control: The improved, intuitive, and responsive touch-screen interface allows you to program with ease and limits the amount of time spent training new users.
Compact footprint: With the increasing popularity of our smaller instruments, we have updated our trusted Veriti Thermal Cycler with a smaller footprint. The VeritiPro Thermal Cycler can fit on just about any workbench with its dimensions of 24.5 cm wide and 46.7 cm deep.

Learn more about the VeritiPro Thermal Cycler ›

Applied Biosystems PCR plastics
Applied Biosystems PCR plastics have been designed and validated to work with our thermal cyclers for more than 25 years. Options for every format and throughput need are available to ensure consistent, precise results for any experiment. To find the best match, please visit our Plastics Selection Guide.

MicroAmp TriFlex 3 x 32-Well PCR Reaction Plates
MicroAmp TriFlex 3 x 32-Well PCR Reaction Plates have a unique design, with three identical polypropylene 32-well PCR plates connected by dual side-tabs for use with 32-well and standard 96-well thermal blocks. The plates offer the same thin-wall construction as all other MicroAmp plastics, for excellent heat transfer from thermal block to sample, and they are validated for use with Applied Biosystems PCR thermal cyclers for optimal fit and performance.

Key features:
• Designed for use with the ProFlex 3 x 32-well PCR System and all Applied Biosystems standard 96-well thermal cyclers
• Easy-to-tear dual side-tabs for simple separation into three individual 32-well plates
• Semi-skirted for easy handling and labeling
• Standard 250 µL working volume, with a 300 µL maximum well volume when used with an adhesive film
• Alphanumeric labeling on each 32-well plate for easy well identification
• Certified human DNA-, DNase-, and RNase-free

MicroAmp Clear Adhesive Films
MicroAmp Clear Adhesive Films create a secure seal across an entire microplate to prevent evaporation and well-to-well contamination.

Key features:
• Adhesive provides tight seal over wells to prevent leaks and evaporation
• Easy to apply and remove
• Available as Clear (economical and sticky) or Optical (ready for real-time PCR and non-tacky)

Rapid Exchange (REX) extended warranty
In most countries, your thermal cycler comes with a standard two-year warranty. The package offered here provides additional warranty coverage to your existing manufacturer’s limited warranty. With the Rapid Exchange (REX) extended warranty, if your instrument needs repair, just call our Support Center and we will exchange it for a factory-certified refurbished replacement instrument within one business day from the time we determine a replacement is required. Instruments are typically received within three days of shipment and are yours to keep. All parts, labor, and shipping charges are included, and existing warranty contracts will be transferred to replacement units.

The Rapid Exchange extended warranty is ideal for customers with user-installable instruments that do not require asset tag consistency, and for those operating under critical timelines.

Certain exclusions apply. Contact your Service and Support Representative for details at service.sales@thermofisher.com.

Gas Mass Flow Controller (MFC) for GXCore Bioprocess Controller, 0–15 SLPM aluminum flow path Thermo Scientific™

The Thermo Scientific Gas Mass Flow Controller (MFC) for the GXCore Bioprocess Controller is a compact assembly providing four mass flow controllers and two associated solenoid valves in an aluminum flow path for gas sparge and overlay. When connected, this MFC is instantly recognized by TruBio software to provide precise control of gas flow for pH and/or dissolved oxygen control.

CaptureSelect™ FcXP MiniChrom Column Thermo Scientific™

CaptureSelect FcXP MiniChrom columns are designed for bench-scale resin screening, process development, and sample preparation. These pre-packed columns are ready to connect and have the following features:
• Dimensions: 1 mL: 0.8 cm D x 2 cm L; 5 mL: 0.8 cm D x 10 cm L
• Direct connection to standard chromatography systems
• Packed with CaptureSelect FcXP Affinity Matrix, offering high dynamic binding capacity

The 1-mL columns can be used for quick screenings of application feasibility and lab scale purification on a convenient and easy-to-use pre-packed column. The 10-cm bed height of the 5-mL columns allows initial process development on a bench scale.

CaptureSelect FcXP Affinity Matrix recognizes the CH3 domain of all human IgG subclasses (IgG1, 2, 3, and 4), enabling purification of all IgG subclasses and Fc fusion proteins directly from complex source materials in a robust and efficient purification process with excellent purity obtained in a single step.

Features of the FcXP affinity matrix include:
• Mild elution, making it suitable for Fc fusion proteins
• One-step purification from crude material with high purity and yield
• Human specific, no binding to bovine antibodies
• Excellent scalability
• Non–animal-derived

View other antibody affinity matrices ›

Free of animal components
Our CaptureSelect affinity products are created by a proprietary technology based on camelid-derived single domain antibody fragments. The FcXP ligand is a 13-kDa single domain fragment comprising the three complementarity determining regions that form the antigen-binding domain, efficiently produced in Saccharomyces cerevisiae in a production process free of animal components.

Main characteristics

Matrix: agarose-based, epoxide-activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect FcXP affinity ligand
Ligand coupling: Epoxide coupling
Binding capacity: 40-50 g IgG/L resin depending on flow rate, column height, and contact time
Elution conditions: 20 mM citric acid or acetic acid, pH 3–4
Column dimensions: 1 mL: 0.8 cm D x 2 cm L; 5 mL: 0.8 cm D x 10 cm L
Flow characteristics: 75–150 cm/h (up to 2 bar)
Formulation buffer: 20% (v/v) ethanol

VeritiPro™ Thermal Cycler + Extended Warranty Package, 96 well, REX Applied Biosystems™

The Applied Biosystems VeritiPro Thermal Cycler delivers proven reliability with advanced temperature control technology and connectivity. Take advantage of next-level PCR optimization with the precision offered by VeriFlex block technology. Connect to the cloud-enabled VeritiPro Thermal Cycler remotely. Conveniently design and securely upload your methods, monitor runs, and check instrument availability from any mobile device or desktop computer using Connect, our cloud-based platform.

Features of the VeritiPro Thermal Cycler include:
Temperature optimization through VeriFlex technology: VeriFlex blocks are controlled by multiple Peltier elements and are used to optimize PCR temperature with precision. The VeritiPro Thermal Cycler allows for six zones of independent temperature control, giving you the ultimate control of your PCR workflows.
Remote capabilities: By connecting your VeritiPro Thermal Cycler to Connect, you will have complete control of your instrument while away from the lab. With Connect you can check instrument availability through the mobile app, download experimental report files, receive alerts, and more. Download our Instrument Connect App updated with this functionality and visit Connect to design and securely upload your methods from any mobile device or desktop computer.
Simulation mode: The VeritiPro Thermal Cycler is equipped with simulation modes, allowing it to be run using the same ramp rates as previous or different instruments. Through this feature you will be able to mimic the ramp rates of the Veriti, Applied Biosystems 2720, Bio-Rad T100, Bio-Rad MyCycler, Bioer XP Cycler, Eppendorf Mastercycler, MJ Research PTC-200, and Takara Dice PCR thermal cyclers.
Our quietest instrument yet: With all the equipment running in the lab, why should your thermal cycler add to the noise level? We have revised the internal instrument technology to provide your lab with a thermal cycler that runs at a noise level of less than 48 dB(A).
8-inch touch-screen control: The improved, intuitive, and responsive touch-screen interface allows you to program with ease and limits the amount of time spent training new users.
Compact footprint: With the increasing popularity of our smaller instruments, we have updated our trusted Veriti Thermal Cycler with a smaller footprint. The VeritiPro Thermal Cycler can fit on just about any workbench with its dimensions of 24.5 cm wide and 46.7 cm deep.

Learn more about the VeritiPro Thermal Cycler ›

Applied Biosystems PCR plastics
Applied Biosystems PCR plastics have been designed and validated to work with our thermal cyclers for more than 25 years. Options for every format and throughput need are available to ensure consistent, precise results for any experiment. To find the best match, please visit our Plastics Selection Guide.

Rapid Exchange (REX) extended warranty
In most countries, your thermal cycler comes with a standard two-year warranty. The package offered here provides additional warranty coverage to your existing manufacturer’s limited warranty. With the Rapid Exchange (REX) extended warranty, if your instrument needs repair, just call our Support Center and we will exchange it for a factory-certified refurbished replacement instrument within one business day from the time we determine a replacement is required. Instruments are typically received within three days of shipment and are yours to keep. All parts, labor, and shipping charges are included, and existing warranty contracts will be transferred to replacement units.

The Rapid Exchange extended warranty is ideal for customers with user-installable instruments that do not require asset tag consistency, and for those operating under critical timelines.

Certain exclusions apply. Contact your Service and Support Representative for details at service.sales@thermofisher.com.

CaptureSelect™ FcXP Affinity Matrix Thermo Scientific™

CaptureSelect FcXP Affinity Matrix is the next-generation CaptureSelect FcXL matrix, specifically designed for higher binding capacity. The selectivity remains identical; the ligand recognizes the CH3 domain of all human IgG subclasses (IgG1, 2, 3, and 4), while maintaining the elution characteristics of CaptureSelect FcXL Affinity Matrix, but the binding capacity is increased (>40 g IgG/L).

Features of this affinity matrix include:
• Mild elution, making it suitable for Fc fusion proteins
• Human-specific, no binding to bovine antibodies
• Excellent scalability
• Non-animal derived

CaptureSelect FcXP Affinity Matrix can be used for the purification of IgG and Fc fusion proteins directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in one step.

View other research scale antibody affinity resins ›

Free of animal components
Our CaptureSelect products are affinity ligands created by a proprietary technology based on camelid-derived single domain antibody fragments. The ligand is a 13-kDa single-domain fragment comprising the three complementarity determining regions (CDRs) that form the antigen-binding domain, efficiently produced in Saccharomyces cerevisiae in a production process free of animal components.

Main characteristics:

Matrix: agarose-based, epoxide activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect FcXP affinity ligand
Ligand coupling method: epoxide coupling
Binding capacity: 40–50 g IgG/L resin depending on flow rate, column height, and contact time
Elution conditions: 20 mM citric acid or acetic acid, pH 3–4, or 100 mM Tris, 2.0 M MgCl2, 40% (v/v) propylene glycol, pH 7
Flow characteristics: 150–300 cm/h (up to 2 bar)
Formulation buffer: 20% (v/v) ethanol

CaptureSelect™ Factor X Affinity Matrix Thermo Scientific™

CaptureSelect Factor X Affinity Matrix was specifically designed for the purification of human Factor X from plasma and recombinant sources.

Features of the CaptureSelect Factor X Affinity Matrix include:
• Highly selective for human Factor X with no affinity for other human plasma proteins
• Binds both Factor X and Factor Xa in the presence of calcium
• Enables efficient purification of Factor X with high yields and retained activity
• Mild elution at neutral pH using EDTA
• Offers excellent scalability
• Non-animal-derived

Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first enzyme in the coagulation cascade to form fibrin. It is a two-chain glycoprotein with a molecular weight of approximately 59 kDa. Factor X normally circulates in the plasma as an inactive molecule with activation of Factor X involved in both the intrinsic and extrinsic coagulation pathways.

View other biosimilars and recombinant protein affinity matrices ›

Free of animal components
CaptureSelect affinity ligands are created using a proprietary technology based on camelid-derived single-domain antibody fragments. The ligand is a 14-kDa fragment comprising the three complementarity determining regions (CDRs) that form the antigen binding domain. The ligand is efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.

Main characteristics

Matrix: agarose-based
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect Factor X affinity ligand
Ligand coupling method: epoxide
Binding capacity: >10 mg/mL resin
Binding conditions: 50 mM Tris, 150 mM NaCl, 5 mM CaCl2, pH 7
Elution conditions: 50 mM Tris, 150 mM NaCl, 5 mM EDTA, pH 7
Flow characteristics: 50–150 cm/h (up to 2 bar)
Formulation buffer: 20% (v/v) ethanol

VeritiPro™ Thermal Cycler + Plastics Package, 96 well, 8-tube strips Applied Biosystems™

The Applied Biosystems VeritiPro Thermal Cycler delivers proven reliability with advanced temperature control technology and connectivity. Take advantage of next-level PCR optimization with the precision offered by VeriFlex block technology. Connect to the cloud-enabled VeritiPro Thermal Cycler remotely. Conveniently design and securely upload your methods, monitor runs, and check instrument availability from any mobile device or desktop computer using Connect, our cloud-based platform.

Features of the VeritiPro Thermal Cycler include:
Temperature optimization through VeriFlex technology: VeriFlex blocks are controlled by multiple Peltier elements and are used to optimize PCR temperature with precision. The VeritiPro Thermal Cycler allows for six zones of independent temperature control, giving you the ultimate control of your PCR workflows.
Remote capabilities: By connecting your VeritiPro Thermal Cycler to Connect, you will have complete control of your instrument while away from the lab. With Connect you can check instrument availability through the mobile app, download experimental report files, receive alerts, and more. Download our Instrument Connect App updated with this functionality and visit Connect, our cloud-based platform, to design and securely upload your methods from any mobile device or desktop computer.
Simulation mode: The VeritiPro Thermal Cycler is equipped with simulation modes, allowing it to be run using the same ramp rates as previous or different instruments. Through this feature you will be able to mimic the ramp rates of the Veriti, Applied Biosystems 2720, Bio-Rad T100, Bio-Rad MyCycler, Bioer XP Cycler, Eppendorf Mastercycler, MJ Research PTC-200, and Takara Dice PCR thermal cyclers.
Our quietest instrument yet: With all the equipment running in the lab, why should your thermal cycler add to the noise level? We have revised the internal instrument technology to provide your lab with a thermal cycler that runs at a noise level of less than 48 dB(A).
8-inch touch-screen control: The improved, intuitive, and responsive touch-screen interface allows you to program with ease and limits the amount of time spent training new users.
Compact footprint: With the increasing popularity of our smaller instruments, we have updated our trusted Veriti Thermal Cycler with a smaller footprint. The VeritiPro Thermal Cycler can fit on just about any workbench with its dimensions of 24.5 cm wide and 46.7 cm deep.

Learn more about the VeritiPro Thermal Cycler ›

Applied Biosystems PCR plastics
Applied Biosystems PCR plastics have been designed and validated to work with our thermal cyclers for more than 25 years. Options for every format and throughput need are available to ensure consistent, precise results for any experiment. To find the best match, please visit our Plastics Selection Guide.

MicroAmp 8-Tube Strips with Attached Domed Caps
MicroAmp 8-Tube Strips with Attached Domed Caps feature individually attached domed caps, dual large end-tabs, and graduated 20-µL markers on each tube to help prevent cross-contamination, pipetting errors, and sample identification errors.

Features include:
• Strip of eight tubes with attached domed caps that open and close independently to prevent contamination and evaporation
• Angled caps that provide efficient tube strip positioning in racks and thermal cycler blocks
• Etched A-H letter labeling on individual tubes that is visible when caps are open or closed
• Dual end tabs for proper labeling and easy handling
• Graduated 20-μL measuring markers on each tube for visual volume verification

CaptureSelect™ IgE EvolveD™ Column Thermo Scientific™

CaptureSelect IgE EvolveD columns are ready-to-use columns designed specifically for use in biopharmaceutical applications. These pre-packed columns are suitable for cGMP manufacturing and have the following features:
• Prepared and packed in a classified ISO7 environment
• An entirely non-metallic flow path
• Qualified in terms of performance and pressure flow characteristics
• Suitable for direct connection to standard chromatography systems
• Available Regulatory Support File
• Packed with CaptureSelect IgE Affinity Matrix, offering high dynamic binding capacity and high resolution over a wide range of flow rates

Please note that CaptureSelect EvolveD affinity columns are made to order. They are custom manufactured two-at-a-time, so are offered only in quantities that are a multiple of two. For detailed information on the resin, please see the CaptureSelect EvolveD column manual below.

Operating and technical specifications
Column type10-cm bed height20-cm bed height
Column diameter (cm)7102071020
Column length (cm)101010202020
Cross-sectional area (cm2)38.578.5314.238.578.5314.2
Column volume (mL)385785314277015706284

• Pressure rating (bar/psi): 4/58
• Operating temperature: 2–30°C, dependent on the resin packed
• Bed support size: 8 µm
• Inlet/outlet internal diameter: 3 mm or 6 mm depending on the column diameter
• Inlet/outlet port connections: 25-mm TC sanitary fitting

View our comprehensive column overview › (Select the Antibody Purification tab.)

CaptureSelect IgE Affinity Matrix is designed for the purification of human IgE (immunoglobuline E) from recombinant and plasma sources.

Features of this affinity matrix include:
• Purification of human IgE, binding different recombinant IgE forms
• IgE specific, no cross-binding to other human immunoglobulins
• Efficient removal of host cell proteins (HCP) and IgE aggregates
• Efficient elution at pH 3.0–3.5
• Excellent scalability
• Non-animal derived

View other biosimilars and recombinant proteins affinity matrices ›

Free of animal components
CaptureSelect products are affinity ligands created with proprietary technology based on camelid-derived single-domain antibody fragments. The IgE ligand is a 13-kDa fragment comprising the three complementarity determining regions (CDRs) that form the antigen binding domain. The ligand is efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.

Main characteristics:

Matrix: agarose-based, epoxide-activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect IgE affinity ligand
Ligand coupling method: epoxide coupling
Binding capacity: >15 g IgE/liter resin depending on flow rate, column height, and contact time
Elution conditions: 20 mM sodium citrate, pH 3.0
Max. operation pressure: 2 bar
Formulation buffer: 20% (v/v) ethanol

MicroSEQ™ ID Microbial Identification Software v3.1.3, Lite, with Software Library Bundle Applied Biosystems™

This software bundle includes MicroSEQ ID Microbial Identification Software Lite v3.1.3, MicroSEQ ID 16S rDNA 500 Microbial Library, MicroSEQ ID 16S rDNA Full Gene Library, and MicroSEQ ID Fungal Gene Library.

MicroSEQ ID Microbial Identification Software, Lite, version 3.1.3, allows you to easily identify and classify bacterial or fungal sequences by comparing them to a validated microbial library (available separately). Theis Lite version of the software is for use on a stand-alone PC (not connected to the genetic analyzer) for data analyses only.

Features of MicroSEQ ID Microbial Identification Software include:
• Automatically identify unknown specimens against a validated microbial library of over 3000 microbial sequences
• Run plates directly on Applied Biosystems 3500 Series genetic analyzers
• Equipped with security, audit, and e-signature features to enable 21 CFR Pt. 11 compliance

Confidently identify microbes
The MicroSEQ ID sequence libraries (available separately) consist of rigorously validated bacterial and fungal libraries to ensure accurate identification. The MicroSEQ ID 16S rDNA 500 Microbial Library consists of over 2300 500-bp 16S rDNA sequences, including extensive coverage of gram-negative non-fermenters, Bacillus, Coryneforms, Mycobacteria, and Staphylococcus. The entries contain the first 500 bases of the 16S rRNA gene, sufficient to identify bacterial unknowns.

The MicroSEQ ID Fungal Gene Library contains 1300 reference sequences from the D2 region of the Large Subunit (rDNA) of yeast and mold species against which an unknown yeast or mold sequence can be compared in order to identify the organism. The MicroSEQ libraries contain information on correctly identified organisms and quality-controlled sequences derived from type strains of curated culture collections. The libraries also support sequence polymorphisms and include bacterial Category A biothreat agents.

Automatically identify unknown specimens
Reviewing each specimen in a project file to make a manual identification call can be tedious and time consuming. The Auto-ID feature in MicroSEQ ID software uses a set of editable parameters to automatically identify unknown specimens. The Results table is displayed in the report with an editable Comments field for additional information or manual identification entries.

Run plates directly
Applied Biosystems 3500 Series genetic analyzer users are able to run plates directly via the MicroSEQ ID software user interface. A single software wizard enables you to set up projects, specimens, and plates; adjust the plate layout via drag and drop; start and monitor the run; and review results.

The MicroSEQ system: a complete, integrated solution
Streamlining every step in microbial identification, the MicroSEQ system combines the advantages of MicroSEQ ID software with easy-to-use PrepMan Ultra sample preparation reagents and protocols, MicroSEQ bacterial and fungal application kits, and industry-leading thermal cyclers and sequencing systems. To help ensure optimal performance and system-wide integration, we develop and test all components of the system together. MicroSEQ ID software also includes security, audit, and electronic signature features, enabling the software to smoothly integrate into your workflow.

VeritiPro™ Thermal Cycler + Extended Warranty + Plastics Package, 96 well, REX, EnduraPlates Applied Biosystems™

The Applied Biosystems VeritiPro Thermal Cycler delivers proven reliability with advanced temperature control technology and connectivity. Take advantage of next-level PCR optimization with the precision offered by VeriFlex block technology. Connect to the cloud-enabled VeritiPro Thermal Cycler remotely. Conveniently design and securely upload your methods, monitor runs, and check instrument availability from any mobile device or desktop computer using Connect, our cloud-based platform.

Features of the VeritiPro Thermal Cycler include:
Temperature optimization through VeriFlex technology: VeriFlex blocks are controlled by multiple Peltier elements and are used to optimize PCR temperature with precision. The VeritiPro Thermal Cycler allows for six zones of independent temperature control, giving you the ultimate control of your PCR workflows.
Remote capabilities: By connecting your VeritiPro Thermal Cycler to Connect, you will have complete control of your instrument while away from the lab. With Connect you can check instrument availability through the mobile app, download experimental report files, receive alerts, and more. Download our Instrument Connect App updated with this functionality and visit Connect to design and securely upload your methods from any mobile device or desktop computer.
Simulation mode: The VeritiPro Thermal Cycler is equipped with simulation modes, allowing it to be run using the same ramp rates as previous or different instruments. Through this feature you will be able to mimic the ramp rates of the Veriti, Applied Biosystems 2720, Bio-Rad T100, Bio-Rad MyCycler, Bioer XP Cycler, Eppendorf Mastercycler, MJ Research PTC-200, and Takara Dice PCR thermal cyclers.
Our quietest instrument yet: With all the equipment running in the lab, why should your thermal cycler add to the noise level? We have revised the internal instrument technology to provide your lab with a thermal cycler that runs at a noise level of less than 48 dB(A).
8-inch touch-screen control: The improved, intuitive, and responsive touch-screen interface allows you to program with ease and limits the amount of time spent training new users.
Compact footprint: With the increasing popularity of our smaller instruments, we have updated our trusted Veriti Thermal Cycler with a smaller footprint. The VeritiPro Thermal Cycler can fit on just about any workbench with its dimensions of 24.5 cm wide and 46.7 cm deep.

Learn more about the VeritiPro Thermal Cycler ›

Applied Biosystems PCR plastics
Applied Biosystems PCR plastics have been designed and validated to work with our thermal cyclers for more than 25 years. Options for every format and throughput need are available to ensure consistent, precise results for any experiment. To find the best match, please visit our Plastics Selection Guide.

MicroAmp EnduraPlates
MicroAmp EnduraPlates offer excellent PCR or qPCR performance in formats developed to meet your experimental needs. They are a solution for work that requires special handling and an even greater degree of durability for use with multi-instrument experiments. They are validated for use with Applied Biosystems PCR thermal cyclers for optimal fit and performance.

Key features:
• Optimized for performance with Applied Biosystems instruments
• Certified DNA-, RNAse-, and PCR inhibitor-free with in-process sampling tests
• Constructed to ANSI/SBS standard, well-suited to high-throughput laboratories and robot handling
• Available in multiple colors for easy organization of laboratory assays
• Excellent mechanical stability and flatness for your complete workflow needs

MicroAmp Clear Adhesive Films
MicroAmp Clear Adhesive Films create a secure seal across an entire microplate to prevent evaporation and well-to-well contamination.

Key features:
• Adhesive provides tight seal over wells to prevent leaks and evaporation
• Easy to apply and remove
• Available as Clear (economical and sticky) or Optical (ready for real-time PCR and non-tacky)

Rapid Exchange (REX) extended warranty
In most countries, your thermal cycler comes with a standard two-year warranty. The package offered here provides additional warranty coverage to your existing manufacturer’s limited warranty. With the Rapid Exchange (REX) extended warranty, if your instrument needs repair, just call our Support Center and we will exchange it for a factory-certified refurbished replacement instrument within one business day from the time we determine a replacement is required. Instruments are typically received within three days of shipment and are yours to keep. All parts, labor, and shipping charges are included, and existing warranty contracts will be transferred to replacement units.

The Rapid Exchange extended warranty is ideal for customers with user-installable instruments that do not require asset tag consistency, and for those operating under critical timelines.

Certain exclusions apply. Contact your Service and Support Representative for details at service.sales@thermofisher.com.

MicroSEQ™ ID Microbial Identification Software v3.1.3, with All Software Libraries Kit Applied Biosystems™

MicroSEQ ID Microbial Identification Software v3.1.3 allows you to easily identify and classify unidentified bacterial or fungal sequences by comparing them to a validated microbial library.

This bundle includes the software USB media and license registration code kit, as well as these bacterial and fungal sequence libraries:
• MSID 16S 500 Microbial Library v2019
• MSID Fungal Library v2018
• MSID V2.0 Full Gene Library
• MSID Supplemental Library v2019

Features of MicroSEQ ID Microbial Identification Software and associated sequence libraries include:
• Automatically identify unknown specimens against a validated microbial library of over 3000 microbial sequences
• Run plates directly on Applied Biosystems 3500 Series genetic analyzers
• Equipped with security, audit, and e-signature features to enable 21 CFR Pt. 11 compliance
• Qualification and validation support available

Confidently identify microbes
The MicroSEQ ID sequence libraries consist of bacterial libraries of 500 bp 16S rDNA sequences and approximately 9300 validated entries, including extensive coverage of gram-negative non-fermenters, Bacillus, Coryneforms, Mycobacteria, and Staphylococcus, as well as a fungal library containing more than 1300 entries. To help ensure accurate identification of the species of your sequences, we rigorously validate all library entries. And unlike other widely available databases, MicroSEQ libraries contain only correctly identified organisms and quality-controlled sequences derived from type strains of preeminent culture collections. The libraries also support sequence polymorphisms and include bacterial Category A biothreat agents.

Automatically identify unknown specimens
Reviewing each specimen in a project file to make a manual identification call can be tedious and time consuming. The Auto-ID feature in MicroSEQ ID software uses a set of editable parameters to automatically identify unknown specimens. The results table is displayed in the report, and an editable comments field allows additional information or manual identifications to be entered into the same table.

Run plates on 3500/3500xL instruments directly via the MicroSEQ ID software
Applied Biosystems 3500 Series genetic analyzer users are now able to run plates on these instruments directly via the MicroSEQ ID software v3.1.3 user interface, without needing Auto-analysis Manager. A single software wizard enables you to set up projects, specimens, and plates; adjust the plate layout via drag and drop; start and monitor the run; and review results.

The MicroSEQ system: a complete, integrated solution
Streamlining every step in microbial identification, the MicroSEQ system combines the advantages of MicroSEQ ID software with easy-to-use PrepMan Ultra sample preparation reagents and protocols, MicroSEQ bacterial and fungal application kits, and industry-leading thermal cyclers and sequencing systems. To help ensure optimal performance and system-wide integration, we develop and test all components of the system together. The MicroSEQ ID software also includes security, audit, and electronic signature features enabling the software to smoothly integrate into your workflow.

Qualification and validation support
To help ensure seamless integration into your laboratory, from installation to routine operation, we offer comprehensive installation and operational qualification (IQ/OQ) and validation support services.

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