Genomics and proteomics search results

Pierce™ Phospho-MAP3K7IP1 pSer423 Antibody (Thermo Scientific™)

MAP3K7IP1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512851
e0addf02dfd2eda9ce3f5360aa0149c5_CmgtBuyProduct

MAP3K7/MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein

MAP3K7 (TAK1) controls transcription regulation and apoptosis, and is implicated in inflammatory disease and rheumatoid arthritis. Fusion of MAP3K7 to MAP3K7IP1 (TAB1) activates MAP3K7. ...

Specifications

Species
Human
Target Gene
mitogen-activated protein kinase kinase kinase 7
Gene Aliases
MAP3K7/MAP3K7IP1 (TAK1-TAB1)
Kinase Group
Ser⁄Thr Kinases: TKL Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_663306, NP_006107
Molecular Weight
45.8 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 437-504
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
MLK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4394
bd4e038b0f249170888ecbc3ac34043b_CmgtBuyProduct

LanthaScreen® Tb-pMAP2K1 (pSer217/221) Antibody Kit

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate ...

Specifications

Format
384-well plate
Gene ID
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Tb (Terbium)
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4813
e855eb49c706e7e710d29bba4250c25f_CmgtBuyProduct

Fluorescein-MAP2K1

Inactive MAP2K1 (MEK1) has been labeled with fluorescein, and is a substrate for MAPK family members. ...

Specifications

Gene ID
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Substrate
MAP2K1
Label or Dye
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
50000 Da
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4812
18eee9eb639a078761b0f1e12691a0b9_CmgtBuyProduct

Pierce™ TAB1 Antibody (Thermo Scientific™)

A suggested positive control is NIH-3T3 cell lysate. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA520084
abea55c49bd58f5470ba235e4c1d3037_CmgtBuyProduct

Pierce™ TAB1 Antibody (Thermo Scientific™)

PA5-28600 targets TAB1 in IF, IHC (P), and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA528600
498725c1447c6cbe312d6721825a7704_CmgtBuyProduct

Pierce™ TAB1 Antibody (Thermo Scientific™)

PA5-28683 targets TAB1 in IF and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA528683
e2cfa94b8f710cd3aa730144508e4991_CmgtBuyProduct

Pierce™ TAB1 Antibody (F.211.6) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514964
3cd18782cb768c2d13d888929a60f852_CmgtBuyProduct

Novex™ TAB1 Antibody (C25E9)

TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferat ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunoprecipitation
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
C25E9
Antibody Fragment
Whole Antibody
Target Gene
TAB1
Gene ID
10454
Gene Symbol
TAB1
Accession Number
Q15750
Gene Aliases
TAB1, MAP3K7IP1, 3'-Tab1
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Adaptor Protein
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
MAPK Signaling
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16572
05eb57e8417361db78c1d85d096469a0_CmgtBuyProduct

Novex™ Phospho-P38 pThr180 / pTyr182 Antibody (Novex™)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and developme ...

Specifications

Reactivity
Human
Rat
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
p38 [pTpY180/182]
Gene ID
1432
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44684G
88992db000516bcf0131f3c3552898f3_CmgtBuyProduct

Novex™ p38-alpha MAP Kinase Antibody (p38-3F11) (Novex™)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and developme ...

Specifications

Reactivity
Human
Mouse
Rat
Monkey
Validated Application
ELISA
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
p38-3F11
Target Gene
p38-alpha MAP Kinase
Gene ID
26416
Label or Dye
Unconjugated
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

331300
91db3f1baccb6f5119f822ee689d6857_CmgtBuyProduct

Novex™ p38 MAPK Antibody (Novex™)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and developme ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
p38 MAPK
Gene ID
26416, 5594
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1202
c616b55b24f65f772f714b7dc930a9a9_CmgtBuyProduct

Pierce™ TAK 1 binding protein 1 Antibody (2D3) (Thermo Scientific™)

A suggested positive control for this product is A431 cells. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
c02f88c895eead72764d058ffea68c65_CmgtBuyProduct

Novex™ Phospho-p38 MAPK pThr180 / pTyr182 Antibody (Novex™)

This antibody is predicted to react with bovine, canine, chicken, mouse, non-human primates and zebrafish based on 100% sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Immunoprecipitation
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
p38 MAPK [pT180/pY182]
Gene ID
1432
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

368500
0600dccc7537fc9c604bbde80b9fedc5_CmgtBuyProduct

Pierce™ p38-alpha MAPK Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517713
f34a20ce89aaa8b7b228a034e5d733a7_CmgtBuyProduct