Genomics and proteomics search results

MAPK1 (ERK2) Recombinant Human Protein, Inactive

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ...

Specifications

Gene ID
5594
Species
Human
Target Gene
mitogen-activated protein kinase 1
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinase Family
Protein Form
Full Length
Inactive
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3314
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MAPK1 (ERK2) Recombinant Human Protein

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinase Family
Protein Form
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3595
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Pierce™ ERK2 / MAPK1 + ERK1 / MAPK3 Antibody (3HCLC), ABfinity™ Rabbit Oligoclonal (Novex™)

This antibody is predicted to react with equine, mouse and rat based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
3HCLC
Antibody Fragment
Whole Antibody
Gene ID
5595
Gene Symbol
MAPK3
Accession Number
P27361
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Volume (Metric)
200 µl
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710214
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Pierce™ ERK2 / MAPK1 + ERK1 / MAPK3 Antibody (6HCLC), ABfinity™ Rabbit Oligoclonal (Novex™)

This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Immunocytochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
6HCLC
Antibody Fragment
Whole Antibody
Target Gene
MAPK (ERK1/2) p44/42 (pT202/pY204)
Gene ID
5595
Gene Symbol
MAPK3
Accession Number
P27361
Gene Aliases
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Label or Dye
Unconjugated
Target Modification State
Phospho
Form
Liquid
Buffer
Phosphate buffered saline (PBS) with 0.09% sodium azide
Other Additives
Sodium Azide Preservative
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710318
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Pierce™ p42 MAP Kinase / ERK2 / MAPK1 Antibody (6F8) (Thermo Scientific™)

MA1-099 has been successfully used in Western blot, ChIP, immunofluorescence, immunohistochemistry and immunoprecipitation applications, and reacts with human, dog, rat, mouse and monkey samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA1099
89e0f34dc58177adef5a5dcd18c3f2e1_CmgtBuyProduct

LanthaScreen® ERK2 U2OS Cell Line

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity, which leads to the sequential phospho-a ...

Specifications

System
LanthaScreen®
Reporter
GFP (EmGFP)
Cell Line
U2OS
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
U0126
Gene Symbol
ERK2
Primary Agonist
EGF
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Optimal Response
EGF (EC50 = 0.83 ng/ml)
Alternate Agonists
PDGF
Orthovanadate
HGF
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1587
01e4b1cdd67c29f4deb250e1570b7dd1_CmgtBuyProduct

Novex™ Phospho-p44 MAPK + p42 MAPK pThr185 + pTyr187 Antibody (Novex™)

ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protei ...

Specifications

Reactivity
Human
Rat
Xenopus
Drosophila
C. elegans
Chicken
Bovine
Mouse
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 [pTpY185/187]
Gene ID
5595
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44680G
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Novex™ ERK1 + ERK2 Antibody (ERK-7D8) (Novex™)

Extracellular signal-regulated kinase 2 (Erk2) is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase MAP kinase 2, p42-MAPK or EGF receptor T669 (ERT1). Mek2 activates Erk2 by phosphorylation of neighbouring threonine-183 and tyrosine-185 re ...

Specifications

Reactivity
Human
Mouse
Rat
Canine
Validated Application
ELISA
Electrophoretic Mobility Shift Assay
Immunoprecipitation
Western Blot
Immunohistochemistry
Host
Mouse
Clonality
Monoclonal
Clone ID
ERK-7D8
Target Gene
ERK1/2 (MAP kinase)
Gene ID
116590
Label or Dye
Unconjugated
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

136200
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Pierce™ Phospho-p44 MAPK + p42 MAPK pThr185 + pTyr187 Antibody (15H10L7), ABfinity™ Rabbit Monoclonal (Novex™)

This antibody is predicted to react with bovine, chicken, chimpanzee, mouse, rat, Xenopus and zebrafish based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Western Blot
Immunohistochemistry
Immunofluorescence
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
15H10L7
Antibody Fragment
Whole Antibody
Target Gene
ERK1/2 [pT185/pY187]
Gene ID
5595, 5594
Accession Number
P27361, P28482
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
For Use With (Equipment)
Confocal Microscope
Fluorescence Microscope
Flow Cytometer
Protein Family
Kinases & Inhibitors
Volume (Metric)
200 µl
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700012
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Novex™ ERK1 + ERK2 Antibody (Novex™)

Extracellular signal-regulated kinase 2 (Erk2) is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase MAP kinase 2, p42-MAPK or EGF receptor T669 (ERT1). Mek2 activates Erk2 by phosphorylation of neighbouring threonine-183 and tyrosine-185 re ...

Specifications

Reactivity
Human
Rat
Mouse
Validated Application
ELISA
Immunoprecipitation
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2
Gene ID
116590, 26413, 26417, 50689, 5594, 5595
Label or Dye
Unconjugated
Purification
Epitope Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

617400
d51fc607358e4a348fb01c583c431c79_CmgtBuyProduct

ERK 1/2 [pT185/pY187] Human Kit for Luminex® Platform (Invitrogen™)

This Singleplex bead kit comprises the analyte specific components for the measurement of ERK1⁄2 (Extracellular signal-Regulated protein Kinase) when phosphorylated at threonine 185 and tyrosine 187 in cell lysates or tissue homogenates. This singleplex bead kit may be multiplex ...

Specifications

Marker
ERK1⁄2 [pTpY185⁄187]
System
Luminex®
Gene ID
5595
Species
Human
Bead Type
Polystyrene
Bead Region
57
Gene Symbol
MAPK3
Sensitivity
0.5 U/ml
Target Gene
mitogen-activated protein kinase 3
Gene Aliases
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, MGC20180, PRKM3, p44-ERK1, p44-MAPK
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NM_002746.2
NP_001103361.1
NP_001035145.1
NP_002737.2
NM_001109891.1
NM_001040056.1
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
For Use With (Equipment)
Luminex® Instruments
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0241
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CellSensor® AP-1-bla ME-180 Cell Line

The CellSensor® AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into ME-180 cells. The cell line was created through FACS sorting of cells responsive to stimulation of the AP-1 pathway with Epidermal G ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1661
503bdf3b8dff78dd86629161dcd64e32_CmgtBuyProduct

ERK1/2 [pTpY185/187] Antibody Pair (Novex™)

This Antibody Pair Kit comes with matched antibody pairs to detect and quantify protein levels of human phosphorylated ERK1⁄2 [pTpT185⁄187] (Extracellular signal-Regulated protein Kinase). Also available is Buffer Kit for Antibody Pairs that saves time with premade, easy-to-use ...

Specifications

Form
Concentrated
Marker
ERK1⁄2 [pTpY185⁄187]
Gene ID
5594, 5595
Reactivity
Human
Gene Symbol
MAPK3
MAPK1
Target Gene
ERK1/2 [pTpY185/187]
Label or Dye
HRP (Horseradish Peroxidase)
Emission Class
Visible
Protein Family
Kinases & Inhibitors
Target Molecule
Proteins (Phosphoproteins)
Research Category
Signal Transduction
Validated Application
ELISA
For Use With (Equipment)
Microplate Reader
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

CHO0095
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Novex™ ERK1 + ERK2 Antibody (Novex™)

ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protei ...

Specifications

Reactivity
Human
Rat
Bovine
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 (pan)
Gene ID
5595
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44654G
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Novex™ Phospho-p44 MAPK + p42 MAPK pThr185 + pTyr187 Antibody, Alexa Fluor® 488 conjugate (Novex™)

ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protei ...

Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 [pTpY185/187]
Gene ID
5595
Label or Dye
Alexa Fluor™ 488
Excitation⁄Emission (nm)
488⁄519
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44680A1
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