Genomics and proteomics search results

LanthaScreen® Tb-anti-PDCD4 [pSer457] Antibody Kit

A part of the PI3K/AKT Pathway, PDCD4 (programmed cell death protein 4) is phosphorylated at Ser457 indirectly via mTORC1 (through the ribosomal protein p70 S6 kinase). ...

Specifications

Reactivity
Human
Label or Dye
Tb (Terbium)
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5105
f1bc3e518fcff100270cce5fc1aa2a7f_CmgtBuyProduct

LanthaScreen® PDCD4 HEK 293E Cell Line

The PI3K⁄AKT⁄mTOR pathway mediates signals for cell growth and survival, transcription and translation, and regulated cell death. The significance of mTOR has been underscored recently by the identification of two distinct cellular complexes: mTORC1 (includes raptor and is rapamy ...

Specifications

System
LanthaScreen®
Readout
End Point
Reporter
GFP (EmGFP)
Cell State
Dividing Cells
Antagonists
IGF-1
PMA
Gene Symbol
PDCD4
Primary Agonist
Insulin
Druggable Target
Kinases
Signaling Pathway
Alternate Agonists
Insulin
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1593
ee6112a488b94e957ab55ee92ac3fbf5_CmgtBuyProduct

Pierce™ PDCD4 Antibody (Thermo Scientific™)

PA5-28150 targets PDCD4 in IF and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA528150
c743ce5883e1e364fa36ea65730220c1_CmgtBuyProduct

Pierce™ PDCD4 Antibody (Thermo Scientific™)

This antibody is predicted to react with mouse, rat, chicken, cow and orangutan based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519734
fe8b6f98afb4611d2e03f84b732ad8f9_CmgtBuyProduct

Pierce™ Phospho-PDCD4 pSer457 Antibody (Thermo Scientific™)

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535543
072bd794522e6a632710a9c99eef698f_CmgtBuyProduct

Pierce™ Phospho-PDCD4 pSer67 Antibody (Thermo Scientific™)

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535544
7f560965937941590d179b35401e0c5b_CmgtBuyProduct

Pierce™ PDCD4 Antibody (Thermo Scientific™)

PA1-30866 detects PDCD4 from human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
5304937941608aa190d19c139e36b7cf_CmgtBuyProduct

Pierce™ PDCD4 Synthetic Peptide (Thermo Scientific™)

This peptide corresponds to 19 amino acids near the carboxy terminus of human PDCD4. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PEP0425
3eb81f88ced6967d9ac7abcd9bf42088_CmgtBuyProduct

Pierce™ PDCD4 Antibody (Thermo Scientific™)

A suggested positive control is A-20 cell lysate. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA520309
83da045e98374cba0432be7f79285e5c_CmgtBuyProduct

Pierce™ Phospho-PDCD4 pSer457 Antibody (Thermo Scientific™)

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
2c78eb81ae4ee4faaca4ea0b121af81f_CmgtBuyProduct

Pierce™ Phospho-PDCD4 pSer67 Antibody (Thermo Scientific™)

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
b7451016960ac4e83d8c5e7750595f95_CmgtBuyProduct

Pierce™ G protein beta subunit like Antibody (Thermo Scientific™)

PA5-30796 targets G protein beta subunit like in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA530796
6ca1b91a98ea47e322b817eca0430ad7_CmgtBuyProduct

Pierce™ Phospho-p70 S6 Kinase pThr421 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535698
2c0e8c2589d0a9321f3e85b66b641349_CmgtBuyProduct

Pierce™ Phospho-p70 S6 Kinase pThr229 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535703
a8844846efdf4e5069e1260a2cd0f866_CmgtBuyProduct

Pierce™ Phospho-p70 S6 Kinase pSer371 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535702
0995c10d1cbb2fc19d109c01616f2d74_CmgtBuyProduct