Genomics and proteomics search results

RAF1 Kinase Inhibitor I (Novex™)

Raf1 Kinase Inhibitor I is a potent inhibitor of c-Raf1. This compound has been assessed with a number of other enzymes, including Cdk1, Cdk2, c-Src, ERK2, MEK, p38 MAPK, Tie2,VEGFR2, and c-fms, and has been found to be >=100-fold more selective for Raf1. ...

Specifications

Form
Solid
Sterility
Nonsterile
Purification
HPLC
Inhibitor Type
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor
Molecular Weight
520.9 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
c-RAF 1
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1263
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Pierce™ RAF1 Antibody (4G4) (Thermo Scientific™)

MA5-17162 targets RAF1 in FACS, IHC, and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA517162
c4a9e81dc51e01ea831d9ff3aad10c23_CmgtBuyProduct

RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein

RAF1 (cRAF) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphory ...

Specifications

Gene ID
4773, 5894
Species
Human
Target Gene
v-raf-1 murine leukemia viral oncogene homolog 1
Gene Aliases
RAF1 (cRAF) Y340D Y341D
Kinase Group
Ser⁄Thr Kinases: TKL Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002871, Y340D, Y341D
Molecular Weight
66.4 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 306-648; Y340D, Y341D
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
RAF Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3805
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Pierce™ Phospho-RAF1 pSer301 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, canine, chicken, mouse, non-human primate and Xenopus based on 100% sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA14639
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Pierce™ Phospho-RAF1 pSer642 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, canine, chicken, human, mouse and non-human primate based on 100% sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA14640
fec4e4b368454b6731163051a0f167b7_CmgtBuyProduct

Pierce™ RAF1 Antibody (Thermo Scientific™)

RAF1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, RAF1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA514941
cf30a389a5f776f07811a0af4351d877_CmgtBuyProduct

Pierce™ Phospho-Raf1 / c-RAF pSer259 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, surviv ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535443
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Pierce™ Phospho-Raf1 / c-RAF pSer296 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, surviv ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535420
b58a8ea4c8d75a7dd6ca22e979f89f80_CmgtBuyProduct

Pierce™ Phospho-Raf1 / c-Raf pSer338 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, surviv ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535811
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Pierce™ Phospho-RAF1 pTyr341 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512905
9e23e5aae67a3656b47f8dbd5fcdce56_CmgtBuyProduct

Pierce™ Phospho-RAF1 pSer296 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512730
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Pierce™ Phospho-RAF1 pSer471 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse, rat and Xenopus based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512767
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Pierce™ Phospho-RAF1 pSer494 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512890
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Pierce™ Phospho-RAF1 pSer339 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512940
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Pierce™ Phospho-RAF1 pSer43 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512765
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