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Novel factors in the pathogenesis of psoriasis and potential drug candidates are found with systems biology approach. Citations & References

  • Authors: Manczinger M, Kemény L
  • Journal: PLoS One
  • PubMed ID: 24303025

Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer. Citations & References

  • Authors: Gyorffy B, Surowiak P, Budczies J, Lánczky A
  • Journal: PLoS One
  • PubMed ID: 24367507

Neutrophils promote the malignant glioma phenotype through S100A4. Citations & References

  • Authors: Liang J, Piao Y, Holmes L, Fuller GN, Henry V, Tiao N, de Groot JF
  • Journal: Clin Cancer Res
  • PubMed ID: 24240114

Cell growth in aggregates determines gene expression, proliferation, survival, chemoresistance, and sensitivity to immune effectors in follicular lymphoma. Citations & References

  • Authors: Gravelle P, Jean C, Familiades J, Decaup E, Blanc A, Bezombes-Cagnac C, Laurent C, Savina A, Fournié JJ, Laurent G
  • Journal: Am J Pathol
  • PubMed ID: 24231431

Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients. Citations & References

  • Authors: Guinney J, Ferté C, Dry J, McEwen R, Manceau G, Kao KJ, Chang KM, Bendtsen C, Hudson K, Huang E, Dougherty B, Ducreux M, Soria JC, Friend S, Derry J, Laurent-Puig P
  • Journal: Clin Cancer Res
  • PubMed ID: 24170544

Meta-analysis and gene set analysis of archived microarrays suggest implication of the spliceosome in metastatic and hypoxic phenotypes. Citations & References

  • Authors: De Meulder B, Berger F, Bareke E, Depiereux S, Michiels C, Depiereux E
  • Journal: PLoS One
  • PubMed ID: 24497970

Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis. Citations & References

  • Authors: Lee JC, Lyons PA, McKinney EF, Sowerby JM, Carr EJ, Bredin F, Rickman HM, Ratlamwala H, Hatton A, Rayner TF, Parkes M, Smith KG
  • Journal: J Clin Invest
  • PubMed ID: 21946256

Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings. Citations & References

  • Authors: Kisselev Alexei F; Kaganovich Daniel; Goldberg Alfred L;
  • Journal: J Biol Chem
  • PubMed ID: 11927581
Catalog # NP0321

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer. Citations & References

  • Authors: Valdés-Mora F, Song JZ, Statham AL, Strbenac D, Robinson MD, Nair SS, Patterson KI, Tremethick DJ, Stirzaker C, Clark SJ
  • Journal: Genome Res
  • PubMed ID: 21788347

Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells. Citations & References

  • Authors: Aldaz B, Sagardoy A, Nogueira L, Guruceaga E, Grande L, Huse JT, Aznar MA, Díez-Valle R, Tejada-Solís S, Alonso MM, Fernandez-Luna JL, Martinez-Climent JA, Malumbres R
  • Journal: PLoS One
  • PubMed ID: 24155920

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression. Citations & References

  • Authors: Buro-Auriemma LJ, Salit J, Hackett NR, Walters MS, Strulovici-Barel Y, Staudt MR, Fuller J, Mahmoud M, Stevenson CS, Hilton H, Ho MW, Crystal RG
  • Journal: Hum Mol Genet
  • PubMed ID: 23842454

Vitamin D receptor, an important transcription factor associated with aldosterone-producing adenoma. Citations & References

  • Authors: Bi C, Li B, Du L, Wang L, Zhang Y, Cheng Z, Zhai A
  • Journal: PLoS One
  • PubMed ID: 24376526

Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma. Citations & References

  • Authors: Bid HK, Kibler A, Phelps DA, Manap S, Xiao L, Lin J, Capper D, Oswald D, Geier B, DeWire M, Smith PD, Kurmasheva RT, Mo X, Fernandez S, Houghton PJ
  • Journal: Clin Cancer Res
  • PubMed ID: 24132923

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6. Citations & References

  • Authors: Brignull LM, Czimmerer Z, Saidi H, Daniel B, Villela I, Bartlett NW, Johnston SL, Meira LB, Nagy L, Nohturfft A
  • Journal: BMC Genomics
  • PubMed ID: 24314139

Gene set bagging for estimating the probability a statistically significant result will replicate. Citations & References

  • Authors: Jaffe AE, Storey JD, Ji H, Leek JT
  • Journal: BMC Bioinformatics
  • PubMed ID: 24330332
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