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TECK/CCL25 Human ELISA Kit (Invitrogen™)

TECK/CCL25 Human ELISA Kit for ELISA

TECK (CCL25) Mouse ELISA Kit (Invitrogen™)

TECK (CCL25) Mouse ELISA Kit for ELISA

CCL4 Human Uncoated ELISA Kit with Plates (Invitrogen™)

This Human CCL4 (MIP-1 beta) Uncoated ELISA Kit with Plates contains the necessary reagents, standards, buffers and diluents for performing quantitative enzyme-linked immunosorbent assays (ELISA). This ELISA kit is specifically engineered for accurate and precise measurement of protein levels from samples including serum, plasma, and supernatants from cell cultures.

CCL4, also known as MIP-1 beta (Macrophage Inflammatory Protein-1 beta), is a member of the CC-subfamily of chemokines and is most closely related to CCL3, or MIP-1 alpha. These proteins play critical roles in the recruitment of leukocytes to the site of inflammation. While both CCL3 and CCL4 are chemoattractant for monocytes, macrophages, and dendritic cells, CCL4 preferentially attracts CD4+ T cells, while CD8+ T cells are more responsive to CCL3. In addition to its chemotactic functions, CCL4 induces the release of proinflammatory cytokine, mast cells degranulation, and NK cell activation.

CCL4 signaling is mediated by the G protein-coupled receptors CCR1, CCR4, and CCR5, which are shared with CCL3 and CCL5 (RANTES). CCR5 is the primary co-receptor for HIV entry, which the virus binds through the gp120 envelope protein. All CCR5 ligands demonstrate potent inhibition of virus entry into the cell, both through steric hindrance of gp120-CCR5 interaction, and ligand-mediated receptor internalization.

Reported Application
ELISA

CCL4 (MIP-1 beta) Human Uncoated ELISA Kit (Invitrogen™)

CCL4 (MIP-1 beta) Human Uncoated ELISA Kit for ELISA

CCL3 (MIP-1 alpha) Human Uncoated ELISA Kit with Plates (Invitrogen™)

CCL3 (MIP-1 alpha) Human Uncoated ELISA Kit with Plates for ELISA

CCL3 (MIP-1 alpha) Human Uncoated ELISA Kit (Invitrogen™)

CCL3 (MIP-1 alpha) Human Uncoated ELISA Kit for ELISA

MCP-1/CCL2 Human Uncoated ELISA Kit with Plates (Invitrogen™)

MCP-1/CCL2 Human Uncoated ELISA Kit with Plates for ELISA

MIP-3 beta Human Uncoated ELISA Kit with Plates (Invitrogen™)

MIP-3 beta Human Uncoated ELISA Kit with Plates for ELISA

MIP-1b (CCL4) Human Instant ELISA™ Kit (Invitrogen™)

MIP-1b (CCL4) Human Instant ELISA™ Kit for ELISA

MCP-1/CCL2 Mouse Uncoated ELISA Kit with Plates (Invitrogen™)

MCP-1/CCL2 Mouse Uncoated ELISA Kit with Plates for ELISA

Eotaxin Mouse ELISA Kit (Invitrogen™)

Eotaxin Mouse ELISA Kit for ELISA

CCL4 (MIP-1 beta) Human Uncoated ELISA Kit with Plates (Invitrogen™)

CCL4 (MIP-1 beta) Human Uncoated ELISA Kit with Plates for ELISA

MCP-1/CCL2 Human Uncoated ELISA Kit (Invitrogen™)

MCP-1/CCL2 Human Uncoated ELISA Kit for ELISA

MCP-1 Rat Instant ELISA™ Kit (Invitrogen™)

MCP-1 Rat Instant ELISA™ Kit for ELISA

RANTES Human Instant ELISA™ Kit (Invitrogen™)

RANTES Human Instant ELISA™ Kit for ELISA