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Genomics researchers have multiple next-generation sequencing (NGS) methods to choose from when designing and implementing their studies. General NGS methods include whole genome sequencing and targeted sequencing , which is further subdivided into exome sequencing and gene or region-specific panels...

The 5500 W Series Genetic Analysis Systems - scalable and accurate next generation sequencing. The 5500 W Series Genetic Analysis Systems support a wide range of applications on a per-lane basis with independently addressable and configurable lanes on either one or two FlowChips.

The field of genomics has expanded greatly in recent years, thanks in large part to advances in DNA sequencing technology. Methods to determine DNA sequences have been an intense area of study since discoveries of the role of DNA as the genetic blueprint and nucleotide structures in the early to...

Preparation of libraries for DNA sequencing for Illumina systems involves multiple steps. In a general workflow, purified DNA is fragmented, end-repaired, and A-tailed; adapters are ligated to the DNA fragments; libraries are amplified if necessary; and the prepared libraries are cleaned,...

Introduction to type IIS restriction enzymes Golden Gate cloning How does Golden Gate Assembly work? Site directed mutagenesis Plasmid-based reverse genetics systems Conclusion , Discovered more than 50 years ago, restriction enzymes are foundational elements of molecular biology and genetic...

Next-generation sequencing (NGS) is a high-throughput methodology that enables rapid sequencing of the base pairs in DNA or RNA samples. Supporting a broad range of applications, including gene expression profiling, chromosome counting, detection of epigenetic changes, and molecular analysis, NGS is...

Abstract Procedure Overview Step 1: Bisulfite Conversion of DNA Step 2: Primer Design Step 3: MS-HRM Optimization Step 4: MS-HRM Standard Curve and Data Analysis Step 5: Sequencing the HRM Product Table References, Download the PDF version of this web page: DNA Methylation Analysis Using...

The Ion Torrent Ion Chef System simplifies the workflow for Ion GeneStudio S5 Series, Ion PGM, and Ion Proton systems, providing an automated, walk-away workflow solution for Ion AmpliSeq library preparation and reproducible template preparation and chip loading.

Find technical resources on NGS fundamentals, covering DNA sequencing history, NGS workflow, DNA and RNA sequencing library preparation, and the basics of sequencing data analysis., Read about the history and overview of DNA sequencing technologies.

Invitrogen streptavidin-coupled Dynabeads are a robust and versatile tool that can be used to capture specific RNA or DNA sequences and then pull them directly out of solution. These monosized superparamagnetic Dynabeads provide an efficient and solid-phase alternative to nitrocellulose and provide...

Perform homogeneous or gradient polyacrylamide gel electrophoresis of nucleic acids or proteins using rigs, casters, plates, spacers, combs, blotters, power supplies, and other accessories of Thermo Scientific™ Owl™ Vertical Gel Electrophoresis Systems.

Mitochondrial DNA sequencing is a useful tool for researchers studying human diseases such as diabetes, certain cancers, and mechanisms of aging. Mitochondrial DNA sequencing is also used in population genetics and biodiversity assessments.

Targeted Sequencing by Sanger Sequencing, Targeted Sequencing by Ion Torrent™ Next-Generation Sequencing, Pre-Designed Primers for PCR and Sanger Sequencing, Targeted sequencing is a rapid and cost-effective way to detect known and novel variants in selected sets of genes or genomic regions.

Mutations in mitochondrial DNA have been linked to diabetes and aging, as well as the development of certain cancers. Mitochondrial DNA resequencing is therefore a useful tool for researchers looking to better understand these diseases.

Our Invitrogen plasmid isolation kits offer options to eliminate the challenges raised by multi sample processing. We design our plasmid DNA extraction products to isolate plasmid DNA at the purity and scale you need.