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EGFR (ErbB1) [L858R] Recombinant Human Protein

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.

Phospho-EGFR (Tyr992) Antibody (3H24L5), ABfinity™ Rabbit Monoclonal (Invitrogen™)

Phospho-EGFR (Tyr992) Monoclonal Antibody for IF, ICC

Phospho-EGFR (Tyr1068) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr1068) Polyclonal Antibody for Western Blot, IF, ICC

EGFR [d746-750] Recombinant Human Protein

Human EGF-R, C-terminal fragment, amino acids H672-A1210 (as in GenBank entry NM_005228.3), amino acids 746-750 deleted, N-terminal GST-HIS6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

EGFR (ErbB1) [T790M] [L858R] Recombinant Human Protein

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The double T790M L858R mutant of EGFR displays resistance to Erlotinib (Tarceva) and sensitivity to HKI-272 and rapamycin combination therapy.

Phospho-EGFR (Tyr845) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr845) Polyclonal Antibody for Western Blot, IF, ICC, IHC

Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody (Thermo Scientific™)

Obtain accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody.

EGFR Antibody (30H45L42), ABfinity™ Rabbit Monoclonal (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IF, ICC, ELISA

EGFR (ErbB1) G719S Recombinant Human Protein (Invitrogen™)

This EGFR (ErbB1) G719S recombinant human protein (695–end) was expressed in insect cells. EGFR receptor tyrosine kinase is a transmembrane glycoprotein. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival. Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms. Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. EGFR (ErbB1) G719S recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

EGFR Multispecies In-Cell ELISA Kit, Colorimetric (Invitrogen™)

EGFR Multispecies In-Cell ELISA Kit, Colorimetric for ELISA

Lab Vision™ Epidermal Growth Factor Receptor (EGFR), Rabbit Monoclonal Antibody (Thermo Scientific™)

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ EGFR, Rabbit Monoclonal Antibody.

Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-11, Mouse Monoclonal Antibody (Thermo Scientific™)

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments.

EGFR Antibody (H9B4) (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IP

EGFR (ErbB1) d747-749 A750P Recombinant Human Protein (Invitrogen™)

This EGFR (ErbB1) d747-749 A750P recombinant human protein (672–end) was expressed in insect cells. EGFR receptor tyrosine kinase is a transmembrane glycoprotein. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival. Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms. Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. EGFR (ErbB1) d747-749 A750P recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

EGFR (ErbB1) T790M C797S L858R Recombinant Human Protein (Invitrogen™)

This EGFR (ErbB1) T790M C797S L858R recombinant human protein (695–end) was expressed in insect cells. EGFR receptor tyrosine kinase is a transmembrane glycoprotein. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival. Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms. Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. EGFR (ErbB1) T790M C797S L858R recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

EGFR (ErbB1) C797S Recombinant Human Protein (Invitrogen™)

This EGFR (ErbB1) C797S recombinant human protein (695–end) was expressed in insect cells. EGFR receptor tyrosine kinase is a transmembrane glycoprotein. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival. Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms. Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. EGFR (ErbB1) C797S recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-10, Mouse Monoclonal Antibody (Thermo Scientific™)

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Phospho-EGFR (Tyr1086) Antibody (11HCLC), ABfinity™ Rabbit Oligoclonal (Invitrogen™)

Phospho-EGFR (Tyr1086) Oligoclonal Antibody for Western Blot, IF, ICC

Phospho-EGFR (Tyr1068) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr1068) Polyclonal Antibody for Western Blot, IF, ICC

Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-5, Mouse Monoclonal Antibody (Thermo Scientific™)

Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, immunoprecipitation and flow cytometry experiments.

EGFR Rabbit Polyclonal Antibody (Invitrogen™)

EGFR SAMPLER PACK PAb hu ; Unconjugated Polyclonal antibody specific to Human EGFR Sampler Pack. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA). Anti-EGFR Sampler Pack recognizes the expressed product of the EGFR gene. Catalog number 44799G is same antibody as former catalog number 44799. 44799G contains 50% glycerol, which improves the stability and longevity of this antibody.

EGFR Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc Tag

Epidermal growth factor receptor (EGFR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 645) of human EGFR (NP_005219) fused to the Fc region of human IgG1 at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA. Immobilized recombinant human EGF at 10 µg/ml (100 µl/well) can bind human EGFR with a linear range of 0.64-400 ng/ml.

Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by SINO Biological.

Phospho-EGFR (Tyr992) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr992) Polyclonal Antibody for Western Blot, IF, ICC, IHC (P)

Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody (Thermo Scientific™)

Ensure accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.

EGFR (Phospho) [pY1068] Human ELISA Kit (Invitrogen™)

EGFR (Phospho) [pY1068] Human ELISA Kit for ELISA

EGFR (ErbB1) G719C Recombinant Human Protein (Invitrogen™)

This EGFR (ErbB1) G719C recombinant human protein (672–end) was expressed in insect cells. EGFR receptor tyrosine kinase is a transmembrane glycoprotein. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival. Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms. Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. EGFR (ErbB1) G719C recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

EGFR (ErbB1) [L861Q] Recombinant Human Protein

The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.

Phospho-EGFR (Tyr1068) Antibody (2H9L3), ABfinity™ Rabbit Monoclonal (Invitrogen™)

Phospho-EGFR (Tyr1068) Monoclonal Antibody for Western Blot, IF, ICC

Phospho-EGFR (Tyr1086) Antibody (11H22L16), ABfinity™ Rabbit Monoclonal (Invitrogen™)

Phospho-EGFR (Tyr1086) Monoclonal Antibody for Western Blot, IF, ICC

EGFR (ErbB1) Recombinant Human Protein

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.

EGFR (ErbB1) [T790M] Recombinant Human Protein

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The T790M mutant of EGFR has arisen in the clinics and displays resistance to Erlotinib (Tarceva) and Gefitinib (Iressa).

Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-15, Mouse Monoclonal Antibody (Thermo Scientific™)

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments.

EGFR Recombinant Human Protein (without Catalytic Activity Domain), His Tag, Insect cell expressed

Epidermal growth factor receptor (EGFR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 642) of human EGFR (NP_005219) fused to a polyhistidine tag at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA. Immobilized human EGF at 10 µg/ml can bind human EGFR with a linear range of 3.2-400 ng/ml.

Formulation: Lyophilized in 20 mM Tris, pH7.4, 50 mM NaCl, 3 mM DTT, 0.5 mM TCEP, 5% Mannitol, 5% Trehalose, 0.02% Tween-80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by SINO Biological.

EGFR Polyclonal Antibody (Invitrogen™)

EGFR Polyclonal Antibody for Western Blot, IF, ICC, IHC, IP

Phospho-EGFR (Tyr1045) Antibody (1HCLC), ABfinity™ Rabbit Oligoclonal (Invitrogen™)

Phospho-EGFR (Tyr1045) Oligoclonal Antibody for Western Blot, IF, ICC

EGFR Multispecies In-Cell ELISA Kit, Near Infrared (Invitrogen™)

EGFR Multispecies In-Cell ELISA Kit, Near Infrared for ELISA

Phospho-EGFR (Tyr1068) Antibody (2HCLC), ABfinity™ Rabbit Oligoclonal (Invitrogen™)

Phospho-EGFR (Tyr1068) Oligoclonal Antibody for Western Blot, IHC (P)

TaqMan™ EGFR Exon 19 Deletions Assay (Applied Biosystems™)

TaqMan® Mutation Detection Assays detect somatic mutations in genes that are associated with cancer. These assays are powered by competitive allele-specific TaqMan® PCR (castPCR™) technology. Specific and sensitive, castPCR™ can detect rare mutated DNA among wild-type DNA.

EGFR (Phospho) [pY1173] Human ELISA Kit (Invitrogen™)

EGFR (Phospho) [pY1173] Human ELISA Kit for ELISA

Phospho-EGFR (Tyr1173) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr1173) Polyclonal Antibody for Western Blot, IF, ICC, IHC (P)

Phospho-EGFR (Tyr1173) Antibody (17H14L5), ABfinity™ Rabbit Monoclonal (Invitrogen™)

Phospho-EGFR (Tyr1173) Monoclonal Antibody for IF, ICC

Phospho-EGFR (Tyr1086) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr1086) Polyclonal Antibody for Western Blot, IF, ICC, IHC, IP, ELISA

EGFR Monoclonal Antibody (me1B3), eFluor 660, eBioscience™ (Invitrogen™)

EGFR Monoclonal Antibody for Flow

Phospho-EGFR (Tyr1148) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr1148) Polyclonal Antibody for Western Blot, IF, ICC

EGFR Antibody (30H45L48), ABfinity™ Rabbit Monoclonal (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IF, ICC

Phospho-EGFR (Tyr1148) Antibody (8HCLC), ABfinity™ Rabbit Oligoclonal (Invitrogen™)

Phospho-EGFR (Tyr1148) Oligoclonal Antibody for Western Blot, IF, ICC

EGFR (Full-length) Human ELISA Kit (Invitrogen™)

EGFR (Full-length) Human ELISA Kit for ELISA

Phospho-EGFR (Tyr1086) Polyclonal Antibody (Invitrogen™)

Phospho-EGFR (Tyr1086) Polyclonal Antibody for Western Blot, IF, ICC, IHC

EGFR Antibody, Alexa Fluor 647 (30H45L8), ABfinity™ Rabbit Monoclonal (Invitrogen™)

EGFR Monoclonal Antibody for IF, ICC

EGFR Antibody, Alexa Fluor 555 (30H45L8), ABfinity™ Rabbit Monoclonal (Invitrogen™)

EGFR Monoclonal Antibody for IF, ICC

EGFR Antibody, Alexa Fluor 488 (30H45L8), ABfinity™ Rabbit Monoclonal (Invitrogen™)

EGFR Monoclonal Antibody for IF, ICC

EGFR Monoclonal Antibody (111.6+199.12+ F4+11E8) (Invitrogen™)

EGFR Cocktail Antibody for Western Blot, IF, ICC, IP

EGFR Monoclonal Antibody (528), Biotin (Invitrogen™)

EGFR Monoclonal Antibody for Flow, IP

EGFR Monoclonal Antibody (528) (Invitrogen™)

EGFR Monoclonal Antibody for IF, ICC, IHC (P), IP

EGFR Monoclonal Antibody (111.6) (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IF, ICC, IHC (P), IP

EGFR Monoclonal Antibody (199.12) (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IF, ICC, IP

EGFR Monoclonal Antibody (H11) (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IF, ICC, IHC (P), Flow, IP

EGFR Monoclonal Antibody (225) (Invitrogen™)

EGFR Monoclonal Antibody for IF, ICC, IP

EGFR Monoclonal Antibody (EGFR.1) (Invitrogen™)

EGFR Monoclonal Antibody for IF, ICC, IHC (F), Flow, IP

EGFR Monoclonal Antibody (111.6), Biotin (Invitrogen™)

EGFR Monoclonal Antibody for Western Blot, IHC (P), IP