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FLT3 Recombinant Human Protein

FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family.

FLT3 [ITD] Recombinant Human Protein

Human FLT3, C-terminal fragment, amino acids R571-S993 (as in NCBI/Protein entry NP_004110.2), internal tandem duplication (oncological mutation: ITD) of aa 591-600 N-terminal GST-HIS6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

FLT3 [D835Y] Recombinant Human Protein

FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family. The FLT3 D835Y mutant is a drug resistant form of FLT3.

FLT3 Ligand Recombinant Human Protein (Gibco™)

Fms-Like Tyrosine Kinase 3 Ligand (FLT3 Ligand, FLT3LG) is a bioactive protein intended for use in cell culture applications. FLT3 Ligand is a cytokine involved in hematopoeisis.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Fms-Like Tyrosine Kinase 3 Ligand is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Fms-Like Tyrosine Kinase 3 Ligand (FLT3 Ligand, FLT3LG) specific activity is determined by the dose dependent proliferation of human OCI-AML5 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

FLT3 Ligand CTS™ Recombinant Human Protein (Gibco™)

Cell Therapy Systems CTS™ Recombinant Human FLT3 ligand is a lyophilized bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. FLT3L (fms-like tyrosine kinase-3 ligand) is a cytokine involved in hematopoeisis. The FLT3 Ligand CTS™ Recombinant Human is expressed in HEK-293 cells and verified for activity through dose-dependent proliferation of human OCI-AML5 cells.

Qualified—helps reduce your burden in qualifying reagents for regulatory submission in cell therapy applications
Highly Pure—minimizes interference from other proteins or contaminants
Active—get more results with less protein

Simplified Transition into Clinical Research
GIBCO® Cell Therapy Systems (CTS™) products are of high quality and supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate. The GIBCO® CTS™ product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our FLT3 Ligand CTS™ Recombinant Human growth factor is determined by the dose-dependent proliferation of human OCI-AML5 cells to have an ED50 range from 0.5–1.0 ng/mL (specific activity: 2.0 × 106–1.0 × 106 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
Cell Therapy Systems Technical Support Web Page
Our Full Collection of GIBCO® CTS™ Growth Factors
Our Full Collection of GIBCO® Growth Factors