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FYN A Recombinant Human Protein

Fyn A (Fyn isoform A) is a member of the SRC tyrosine kinase oncogene family showing high homology to YES1, FGR and SRC. Fyn has been shown to phosphorylate Dab1, an intracellular adaptor protein that interacts with amyloid precursor protein (APP) and apoE receptor 2 (apoEr2). The interaction of Fyn and Dab1 regulates the phosphorylation, trafficking, and processing of APP and apoEr2. Fyn expression has been shown to be significantly increased in Chronic Myelogenous Leukemia (CML). Knockdown of Fyn with shRNA slows leukemia cell growth, inhibits clonogenicity, and leads to increased sensitivity to imatinib. Full-length recombinant human FYN A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

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LanthaScreen® Eu Kinase Binding Assay

FYN Recombinant Human Protein

FYN is a SRC-related kinase expressed in brain, skeletal muscle and adipose tissues. Fyn functions in a large number of pathways and has been shown to play a role in memory.

Fyn Monoclonal Antibody (Fyn-1S) (Invitrogen™)

Fyn Monoclonal Antibody for Western Blot, IF, IP, ELISA

Fyn Polyclonal Antibody (Invitrogen™)

Fyn Polyclonal Antibody for Western Blot, IF, ICC, IHC (P)

Fyn Monoclonal Antibody (1S) (Invitrogen™)

Fyn Monoclonal Antibody for Western Blot, IHC (P), IP

Fyn Monoclonal Antibody (1S) (Invitrogen™)

Fyn Monoclonal Antibody for Western Blot, IHC (P)

Phospho-Fyn (Tyr530) Polyclonal Antibody (Invitrogen™)

Phospho-Fyn (Tyr530) Polyclonal Antibody for Western Blot, IHC (P), IP

Fyn Monoclonal Antibody (2A10) (Invitrogen™)

Fyn Monoclonal Antibody for Western Blot, IF, ICC, IHC, Flow

Fyn Polyclonal Antibody (Invitrogen™)

Fyn Polyclonal Antibody for Western Blot, IHC, Flow

Fyn Polyclonal Antibody (Invitrogen™)

Fyn Polyclonal Antibody for Western Blot

Fyn Polyclonal Antibody (Invitrogen™)

Fyn Polyclonal Antibody for Western Blot, IHC (P)

Fyn Polyclonal Antibody (Invitrogen™)

Fyn Polyclonal Antibody for Western Blot

Fyn Monoclonal Antibody (2H8) (Invitrogen™)

Fyn Monoclonal Antibody for Western Blot

Phospho-Fyn (Tyr530) Polyclonal Antibody (Invitrogen™)

Phospho-Fyn (Tyr530) Polyclonal Antibody for Western Blot, IHC (P)

Fyn Monoclonal Antibody (FYN-01) (Invitrogen™)

Fyn Monoclonal Antibody for Western Blot, ICC, IHC (P), IP