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ProPac HIC-10 Column Manual / Product Insert

What are the benefits of POROS chromatography resins in a manufacturing process? Product FAQ


Increased titers and product demand have caused substantial bottlenecks in downstream processing for a range of biomolecules. POROS chromatography resins address these challenges with solutions that help maintain performance and add process flexibility. Due to the polymeric nature of the backbone and the way we attach the ligands, the beads have very robust physical and chemical stability. This allows for aggressive solutions to be used, if needed, to improve cleanability and thereby increase resin lifetime/reuse. Our ion exchange resins are the go-to resins in downstream monoclonal antibody and recombinant protein chromatography where capacity, resolution, and yield are critical. We are also working on a new line of hydrophobic interaction resins that may be of interest for future projects that will be a best-in-class product for capacity and resolution with an added benefit of being able to load under lower salt concentrations and faster flow rates. We are also a strong partner when it comes to quality and supply of our products.

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Noncovalent interactions of the Apple 4 domain that mediate coagulation factor XI homodimerization. Citations & References

  • Authors: Dorfman R, Walsh PN
  • Journal: J Biol Chem
  • PubMed ID: 11092900
Catalog #

Characterization of the purified Chlamydomonas minus agglutinin. Citations & References

  • Authors: Collin-Osdoby P, Adair WS
  • Journal: J Cell Biol
  • PubMed ID: 2411736
Catalog # A821

Conformational changes of an Hsp70 molecular chaperone induced by nucleotides, polypeptides, and N-ethylmaleimide. Citations & References

  • Authors: Chirico WJ, Markey ML, Fink AL
  • Journal: Biochemistry
  • PubMed ID: 9753476
Catalog # A47

Site-specific chemical modification of interleukin-1 beta by acrylodan at cysteine 8 and lysine 103. Citations & References

  • Authors: Yem AW, Epps DE, Mathews WR, Guido DM, Richard KA, Staite ND, Deibel MR
  • Journal: J Biol Chem
  • PubMed ID: 1531337
Catalog # A433

Qdot Nanocrystals—Section 6.6 Molecular Probes Handbook

Calcium Regulation—Section 17.2 Molecular Probes Handbook

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