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Lab Vision™ IGF-1R (α -Subunit) Ab-1, Mouse Monoclonal Antibody (Thermo Scientific™)

Provide accurate, reproducible results with the Thermo Scientific™ IGF-1R (α-Subunit) Ab-1, Mouse Monoclonal Antibody.

Lab Vision™ IGF-1R (α -Subunit) Ab-4, Mouse Monoclonal Antibody (Thermo Scientific™)

Ideal for immunoprecipitation, Thermo Scientific™ IGF-1R (α-Subunit) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

LanthaScreen™ IGF-1R GripTite™ Cell Line

The IGF-1R⁄PI3K⁄AKT pathway mediates signals for cell growth, cell survival, transcription, translation, and glucose uptake. IGF-1R is a receptor tyrosine kinase (RTK) that resides at the top of the pathway. Upon growth factor binding extracellularly, this RTK undergoes auto-phosphorylation at multiple intracellular tyrosine residues (resulting in pathway activation). The LanthaScreen® IGF-1R GripTite™ (HEK 293 MSR) cellular assay utilizes a human cell line that constitutively expresses IGF-1R fusion proteins with yellow fluorescent protein (YFP). This kinase target was introduced using lipid transfection and these cells are a clonal population isolated by FACS, using YFP fluorescence as a sorting marker and Blasticidin to maintain cells under selection. Using this cell line, a homogenous immunoassay was developed with a time-resolved FRET (TR-FRET) readout in which the insulin-induced phosphorylation of multiple tyrosine residues on IGF-1R is detected in cell lysates using a generic terbium-labeled phosphospecific antibody (Tb-anti-pY20). This cell line has been validated with different stimuli⁄inhibitors and shows correct EC50 ⁄ IC50 values. Moreover, this assay has been optimized for performance under variable experimental conditions (including cell plating density, agonist stimulation time, DMSO tolerance and assay development time) and displays excellent statistical data (Z' > 0.6) and good signal-to-background.

TaqMan™ Array, Human IGF-1R Signaling, Fast 96-well (Applied Biosystems™)

These 96-well plates are pre-configured with the most appropriate TaqMan® Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of an entire gene signature in one simple experiment. The TaqMan® Array Human IGF1R Signaling 96-well Plate contains 92 assays to genes associated with IGF1R signaling and 4 assays to candidate endogenous control genes.

IGF1 Monoclonal Antibody (126002) (Invitrogen™)

IGF1 Monoclonal Antibody for Western Blot, ELISA, Neu

IGF1 Recombinant Rabbit Monoclonal Antibody (23) (Invitrogen™)

IGF1 Recombinant Monoclonal Antibody for ELISA

IGF1 Receptor Recombinant Protein (Invitrogen™)

Human IGF1R beta Recombinant Protein for Ctrl

IGF1 Monoclonal Antibody (56408) (Invitrogen™)

IGF1 Monoclonal Antibody for Western Blot, ELISA

IGF1 Monoclonal Antibody (OTI4B12), TrueMAB™ (OriGene)

IGF1 Monoclonal Antibody for Western blot, IHC (P)

IGF1 Monoclonal Antibody (OTI3A5), TrueMAB™ (OriGene)

IGF1 Monoclonal Antibody for Western blot

IGF1 Monoclonal Antibody (OTI3A5), TrueMAB™ (OriGene)

IGF1 Monoclonal Antibody for Western blot

IGF1 Monoclonal Antibody (OTI3A6), TrueMAB™ (OriGene)

IGF1 Monoclonal Antibody for Western blot, IHC (P)

IGF1 Monoclonal Antibody (OTI3A6), TrueMAB™ (OriGene)

IGF1 Monoclonal Antibody for Western blot, IHC (P)

IGF1 Monoclonal Antibody (OTI4B12), TrueMAB™ (OriGene)

IGF1 Monoclonal Antibody for Western blot, IHC (P)

IGF1 Monoclonal Antibody (1C5-1A2) (Invitrogen™)

IGF1 Monoclonal Antibody for Western Blot, ELISA

IGF1 Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-like Growth Factor 1 (IGF1) is a bioactive protein intended for use in cell culture applications. IGF1 binds its receptor, IGF1R, activating several signaling pathways. IGF1 has been shown to be involved in proliferation, differentiation, survival, growth, apoptosis and regeneration. This is the 20 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Insulin-like Growth Factor 1 (IGF1) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor 1 (IGF1) specific activity is determined by its ability to stimulate the proliferation of mouse FDC-P1 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

IGF1 Polyclonal Antibody (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, ELISA

IGF-1 Mouse ELISA Kit (Invitrogen™)

IGF-1 Mouse ELISA Kit for ELISA

IGF-I Recombinant Mouse Protein (Gibco™)

Recombinant IGF-I is a bioactive protein intended for use in cell culture applications. IGF-I is involved in a number of biological processes and acts upon a number of cell types including hepatocytes, chondrocytes, and epithelial cells.

IGF-1 Rat ELISA Kit (Invitrogen™)

IGF-1 Rat ELISA Kit for ELISA

IGF-2 Mouse ELISA Kit (Invitrogen™)

IGF-2 Mouse ELISA Kit for ELISA

IGF-II Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-Like Growth Factor-2 (IGF-II) is a bioactive protein intended for use in cell culture applications. IGF-II is involved in a number of biological processes and acts upon a number of cell types including hepatocytes, chondrocytes, and epithelial cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Insulin-Like Growth Factor-2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Insulin-Like Growth Factor-2 (IGF-II) specific activity is determined by the dose dependent proliferation of FDC-P1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IGF1 Monoclonal Antibody (M23) (Invitrogen™)

IGF1 Monoclonal Antibody for Western Blot

IGF1 (rat) Recombinant Protein (Invitrogen™)

Rat IGF1 Recombinant Protein for Ctrl

IGF1 (mouse) Recombinant Protein (Invitrogen™)

Mouse IGF1 Recombinant Protein for Ctrl

IGF1 Polyclonal Antibody (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, IHC, pep-ELISA

Human IGF1 Recombinant Protein (Invitrogen™)

Human IGF1 Recombinant Protein for Ctrl

IGF1 Polyclonal Antibody (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, ELISA, Neu

IGF1 Polyclonal Antibody, Biotin (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, ELISA

IGF1 Monoclonal Antibody (2C8) (Invitrogen™)

IGF1 Monoclonal Antibody for Western Blot

IGF1 Monoclonal Antibody (7973) (Invitrogen™)

IGF1 Monoclonal Antibody for IHC (F), IHC (P), ELISA, RIA

IGF1 Polyclonal Antibody (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, ELISA, FN

IGF1 Monoclonal Antibody (M23/ILG1-001) (Invitrogen™)

IGF1 Monoclonal Antibody for ELISA, RIA

IGF1 Polyclonal Antibody (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, ELISA

IGF1 Monoclonal Antibody (3B7) (Invitrogen™)

IGF1 Monoclonal Antibody for IP

IGF1 Polyclonal Antibody (Invitrogen™)

IGF1 Polyclonal Antibody for Western Blot, IF, ICC, IHC (P)

IGF1 Recombinant Protein (Invitrogen™)

Human IGF1 Recombinant Protein for Ctrl

IGF1R beta Monoclonal Antibody (194Q13) (Invitrogen™)

IGF1R beta Monoclonal Antibody for Western Blot

IGFBP-3 Mouse ELISA Kit (Invitrogen™)

IGFBP-3 Mouse ELISA Kit for ELISA

IGFBP4 Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-like Growth Factor Binding Protein 4 (IGFBP4) is a bioactive protein intended for use in cell culture applications. IGFBP4 binds IGF1 and II, prolonging these growth factors' half life and altering the way these growth factors interact with cells surface receptors. This is the 100 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Insulin-like Growth Factor Binding Protein 4 (IGFBP4) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor Binding Protein 4 (IGFBP4) specific activity is determined the dose dependent inhibition of IGF-II induced proliferation of MCF-7 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related Links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

IGFBP-5 Mouse ELISA Kit (Invitrogen™)

IGFBP-5 Mouse ELISA Kit for ELISA

IGFBP6 Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-like Growth Factor Binding Protein 6 (IGFBP6) is a bioactive protein intended for use in cell culture applications. IGFBP6 binds IGF-1 and II, prolonging these growth factors’ half life and altering the way these growth factors interact with cells surface receptors. This is the 10 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Insulin-like Growth Factor Binding Protein 6 (IGFBP6) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor Binding Protein 6 (IGFBP6) specific activity is determined the dose dependent inhibition of IGF-II induced proliferation of MCF-7 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related Links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

IGF2R Monoclonal Antibody (2G11) (Invitrogen™)

IGF2R Monoclonal Antibody for Western Blot, IF, ICC, IHC (PFA), Flow, IP

IGFBP-6 Mouse ELISA Kit (Invitrogen™)

IGFBP-6 Mouse ELISA Kit for ELISA

Phospho-IR/IGF1R (Tyr1158, Tyr1162, Tyr1163) Polyclonal Antibody (Invitrogen™)

Phospho-IR/IGF1R (Tyr1158, Tyr1162, Tyr1163) Polyclonal Antibody for Western Blot

IGF1R Human ELISA Kit (Invitrogen™)

IGF1R Human ELISA Kit for ELISA

IGF1R Recombinant Human Protein

IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers.

Phospho-IR/IGF1R (Tyr1162, Tyr1163) Recombinant Rabbit Monoclonal Antibody (97H9L7) (Invitrogen™)

Phospho-IR/IGF1R (Tyr1162, Tyr1163) Recombinant Monoclonal Antibody for Western Blot, ELISA

Phospho-IR/IGF1R (Tyr1158) Polyclonal Antibody (Invitrogen™)

Phospho-IR/IGF1R (Tyr1158) Polyclonal Antibody for Western Blot, IF, ICC, IHC

Phospho-IGF1R beta (Tyr1135, Tyr1136) Recombinant Rabbit Monoclonal Antibody (15H10L8) (Invitrogen™)

Phospho-IGF1R beta (Tyr1135, Tyr1136) Recombinant Monoclonal Antibody for Western Blot

IGFBP5 Rat ELISA Kit (Invitrogen™)

IGFBP5 Rat ELISA Kit for ELISA

Phospho-IR/IGF1R (Tyr1162, Tyr1163) Polyclonal Antibody (Invitrogen™)

Phospho-IR/IGF1R (Tyr1162, Tyr1163) Polyclonal Antibody for Western Blot, IF, ICC, IHC

IGFBP2 Human ELISA Kit (Invitrogen™)

IGFBP2 Human ELISA Kit for ELISA

IGF2R Polyclonal Antibody (Invitrogen™)

IGF2R Polyclonal Antibody for Western Blot, IF, ICC, DB

IGFBP1 Human ELISA Kit (Invitrogen™)

IGFBP1 Human ELISA Kit for ELISA

IGF1R alpha Monoclonal Antibody (24-31) (Invitrogen™)

IGF1R alpha Monoclonal Antibody for IF, ICC, IP, ELISA

IGF1R alpha Monoclonal Antibody (17-69) (Invitrogen™)

IGF1R alpha Monoclonal Antibody for IP, IA

IGF1R alpha Monoclonal Antibody (24-31), Biotin (Invitrogen™)

IGF1R alpha Monoclonal Antibody for IF, ICC, IHC (P), IP, ELISA

IGF1R alpha Monoclonal Antibody (24-57) (Invitrogen™)

IGF1R alpha Monoclonal Antibody for IP, IA

IGF1R beta Monoclonal Antibody (1-2) (Invitrogen™)

IGF1R beta Monoclonal Antibody for Western Blot