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ALK Recombinant Human Protein

Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily. It is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer. Chromosomal rearrangement is the most common genetic alteration.

Learn more about our kinase proteins >

Related Links:

LanthaScreen® Kinase Activity Assay
LanthaScreen® Eu Kinase Binding Assay

IGF1 Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-like Growth Factor 1 (IGF1) is a bioactive protein intended for use in cell culture applications. IGF1 binds its receptor, IGF1R, activating several signaling pathways. IGF1 has been shown to be involved in proliferation, differentiation, survival, growth, apoptosis and regeneration. This is the 100 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Insulin-like Growth Factor 1 (IGF1) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor 1 (IGF1) specific activity is determined by its ability to stimulate the proliferation of mouse FDC-P1 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

LTK (TYK1) Recombinant Human Protein

LTK (TYK1) is a member of the ros⁄insulin receptor family of kinases involved in cell growth and differentiation.

FGF-Basic (AA 1-155) Recombinant Human Protein (Gibco™)

FGF-Basic (AA 1-155) is a bioactive protein intended for use in cell culture applications. Fibroblast growth factor-basic is known as FGF-basic, bFGF, FGF 2, FGF-β, and heparin binding growth factor. FGF-basic is involved in a number of biological processes, including embryonic development and differentiation, neuron differentiation, survival, regeneration, and the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. Features of recombinant human FGF-basic:

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—proteins bioassayed with Gibco® media

High-purity, recombinant, bioactive protein
Human FGF-basic (AA 1-155) is one of our more than 250 available recombinant proteins. To help ensure our growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human FGF-basic specific activity is determined by the dose dependent proliferation of BALB/3T3 cells.

Proven compatibility
Our recombinant proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

IGFBP4 Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-like Growth Factor Binding Protein 4 (IGFBP4) is a bioactive protein intended for use in cell culture applications. IGFBP4 binds IGF1 and II, prolonging these growth factors' half life and altering the way these growth factors interact with cells surface receptors. This is the 10 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Insulin-like Growth Factor Binding Protein 4 (IGFBP4) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor Binding Protein 4 (IGFBP4) specific activity is determined the dose dependent inhibition of IGF-II induced proliferation of MCF-7 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related Links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

IGF-II Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-Like Growth Factor-2 (IGF-II) is a bioactive protein intended for use in cell culture applications. IGF-II is involved in a number of biological processes and acts upon a number of cell types including hepatocytes, chondrocytes, and epithelial cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Insulin-Like Growth Factor-2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Insulin-Like Growth Factor-2 (IGF-II) specific activity is determined by the dose dependent proliferation of FDC-P1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IGFBP6 Recombinant Human Protein (Gibco™)

Recombinant Human Insulin-like Growth Factor Binding Protein 6 (IGFBP6) is a bioactive protein intended for use in cell culture applications. IGFBP6 binds IGF-1 and II, prolonging these growth factors’ half life and altering the way these growth factors interact with cells surface receptors. This is the 10 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Insulin-like Growth Factor Binding Protein 6 (IGFBP6) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor Binding Protein 6 (IGFBP6) specific activity is determined the dose dependent inhibition of IGF-II induced proliferation of MCF-7 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related Links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

FGF-Basic Full Length CTS™ Recombinant Human Protein (Gibco™)

Cell Therapy Systems CTS™ Recombinant Human FGF-basic (full length) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. FGF-basic (FGFb), is involved in a number of biological processes including embryonic development and differentiation, and neuron differentiation, survival, and regeneration. FGFb is also involved in the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. The lyophilized, E. coli-expressed FGF-basic (full length) CTS™ Recombinant Human is verified for activity through dose-dependent proliferation of BALB/3T3 cells.

Qualified—helps reduce your burden in qualifying reagents for regulatory submission in cell therapy applications
Highly Pure—minimizes interference from other proteins or contaminants
Active—get more results with less protein

Simplified Transition into Clinical Research
GIBCO® Cell Therapy Systems (CTS™) products are of high quality and supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate. The GIBCO® CTS™ product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our FGF-basic (full length) CTS™ Recombinant Human growth factor is determined by the dose-dependent proliferation of BALB/3T3 cells to have an ED50 range of 0.1–1.0 ng/mL (specific activity: 1.0 × 107–1.0 × 106 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.

Related Links

Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
Cell Therapy Systems Technical Support Web Page
Our Full Collection of GIBCO® CTS™ Growth Factors
Our Full Collection of GIBCO® Growth Factors

FGF-Basic (AA 10-155) Recombinant Human Protein (Gibco™)

FGF-Basic (AA 10-155) is a bioactive protein intended for use in cell culture applications. Fibroblast growth factor-basic is known as FGF-basic, bFGF, FGF 2, FGF-β, and heparin binding growth factor. FGF-basic is involved in a number of biological processes, including embryonic development and differentiation, neuron differentiation, survival, regeneration, and the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin.

Features of recombinant human FGF-basic:

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—proteins bioassayed with Gibco® media

High-purity, recombinant, bioactive protein
Human FGF-basic (AA 10-155) is one of our more than 250 available recombinant proteins. To help ensure our growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human FGF-basic specific activity is determined by the dose dependent proliferation of BALB/3T3 cells.

Proven compatibility
Our recombinant proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

FGF Basic Recombinant Human Protein, Animal-Origin Free (Gibco™)

Recombinant Human Fibroblast Growth Factor Basic (also known as FGF Basic, bFGF, FGF 2, FGF-β or Heparin Binding Growth Factor) is a bioactive protein intended for use in cell culture applications. FGF Basic is used in studies of angiogenesis, mitogenesis of fibroblasts, neurite outgrowth in PC-12 cells, receptor binding, and tyrosine protein kinase phosphorylation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Fibroblast Growth Factor Basic is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Fibroblast Growth Factor Basic (FGF Basic, bFGF) specific activity is determined by thymidine incorporation into serum-starved Balb/c 3T3 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.