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Technical Guide: Confident. Concise. Comprehensive. Robust LC-MS Workstream for Toxicology Analysis Product Literature

Immunoassay reagents for thyroid testing. 1. Synthesis of thyroxine conjugates. Citations & References

  • Authors: Adamczyk M, Fino L, Fishpaugh JR, Johnson DD, Mattingly PG
  • Journal: Bioconjug Chem (1994) 5:459-462
  • PubMed ID: 7849077
Catalog # A1353

Development and testing of radio and enzyme immunoassays for acidic fibroblast growth factor (aFGF). Citations & References

  • Authors: Caruelle D, Grassi J, Courty J, Groux-Muscatelli B, Pradelles P, Barritault D, Caruelle JP
  • Journal: Anal Biochem (1988) 173:328-339
  • PubMed ID: 3056106
Catalog #
  • S1534
  • S1553(Discontinued)

Global Drug Abuse Trends: A summary of Journal publications on drugs of abuse testing immunoassays Product Literature

Testing UK blood donors for exposure to human parvovirus 4 using a time-resolved fluorescence immunoassay to screen sera and Western blot to confirm reactive samples. Citations & References

  • Authors: Maple PA, Beard S, Parry RP, Brown KE
  • Journal: Transfusion 2013; (): -
  • PubMed ID: 23721256
Catalog #

Brochure: CEDIA & DRI Drugs of Abuse Testing Immunoassays Brochure [EN] Product Literature

Smart Note: Can immunoassay plates help in SARS-CoV-2 research? Product Literature

Catalog: MAS Quality Controls Product Catalog [EN] Product Literature

Oral Fluids Drugs of Abuse Immunoassay Brochure Product Literature

Drug Monitoring, Quality Controls and Instrumentation Catalog 2018 [EN] Product Literature

Oral Fluid Testing Benefits and Ordering Information Product Literature

What is the difference between laboratory (observed) units and international units? Product FAQ

Answer

Laboratory units are the actual values obtained from running an assay with a particular protein in an assay in your lab; i.e., the activity (ED50) you observe on your target cells. ‘International' units are consensus values of potency derived from a collaborative NIBSC effort to standardize reported use of proteins. These values are derived from bioassay testing of the same protein by many target cell types/substrains. It is very likely that the ‘laboratory' units you observe and the NIBSC values will not correlate 1:1; e.g., it might take 0.1 - 20 U/mL to see 1 U/mL in your experiment. These are bioassay standards describing potency in bioassay only. The mass values assigned to these are not hard values and use of these for immunoassay standardization is of limited value unless assays calibrated by the NIBSC standard use the same capture and detection antibody clones.

Answer Id:: E14505

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Which polystyrene microspheres can be used for an agglutination test? Product FAQ

Answer

We do not have any formal recommendations to provide. The choice depends upon the mode of detection (by eye or microscopy; colorimetric or fluorescence), the color, and the material to be bound upon the surface of the beads (the appropriate surface modification on the bead for either passive or covalent attachment).
Here are some references on this topic:
- Wanger, et al., Chapter 11 - Antigen and Antibody Testing. Microbiology and Molecular Diagnosis in Pathology, A Comprehensive Review for Board Preparation, Certification and Clinical Practice, 2017, 221-232
- Cantarero LA, Butler JE, and Osborne JW, The Adsorptive Characteristics of Proteins for Polystyrene and their Significance in Solid-Phase Immunoassays, Anal Biochem, 1980, 105:375-382
- Kawaguchi H, Sakamoto K, Ohtsuka Y, et al., Fundamental Study on Latex Reagents for Agglutination Tests, Biomat, 1989, 10:225-229

Answer Id:: E18309

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