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Phospho-JAK1 (Tyr1022, Tyr1023) Polyclonal Antibody (Invitrogen™)

Phospho-JAK1 (Tyr1022, Tyr1023) Polyclonal Antibody for Western Blot, IF, ICC

JAK1 Recombinant Human Protein

Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways.

Phospho-JAK1 (Tyr1022, Tyr1023) Recombinant Rabbit Monoclonal Antibody (59H4L5) (Invitrogen™)

Phospho-JAK1 (Tyr1022, Tyr1023) Recombinant Monoclonal Antibody for Western Blot, IF, ICC, ChIP

JAK1 Polyclonal Antibody (Invitrogen™)

JAK1 Polyclonal Antibody for IHC (P)

Phospho-JAK1 (Tyr1022) Polyclonal Antibody (Invitrogen™)

Phospho-JAK1 (Tyr1022) Polyclonal Antibody for Western Blot, IHC (P)

Phospho-JAK1 (Tyr1022) Polyclonal Antibody (Invitrogen™)

Phospho-JAK1 (Tyr1022) Polyclonal Antibody for Western Blot, IHC (P)

JAK1 Polyclonal Antibody (Invitrogen™)

JAK1 Polyclonal Antibody for Western Blot

JAK1 Polyclonal Antibody (Invitrogen™)

JAK1 Polyclonal Antibody for Western Blot, IF, ICC

Phospho-JAK1 (Tyr1022, Tyr1023) Polyclonal Antibody (Invitrogen™)

Phospho-JAK1 (Tyr1022, Tyr1023) Polyclonal Antibody for Western Blot

JAK1 Polyclonal Antibody (Invitrogen™)

JAK1 Polyclonal Antibody for Western Blot

JAK1 Polyclonal Antibody (Invitrogen™)

JAK1 Polyclonal Antibody for Western Blot

JAK1 Monoclonal Antibody (3H7A8) (Proteintech)

JAK1 Monoclonal Antibody for Western Blot, IHC (P)

JAK1 Recombinant Rabbit Monoclonal Antibody (JM75-03) (Invitrogen™)

JAK1 Recombinant Monoclonal Antibody for Western Blot, IHC, Flow

CellSensor™ GAS-bla ME-180 Cell Line

The CellSensor® GAS-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Gamma Activated Sequence (GAS) response element stably integrated into ME-180 cells. To construct this cell line, the GAS-bla construct was transduced into ME-180 cells by lentivirus. Flow cytometry was used to isolate cells responsive to Interferon Gamma (IFN-γ). This cell line is validated for DMSO tolerance, cell number, stimulation time, substrate loading time, as well as Z'and EC50 concentrations for IFN-&gamma. The CellSensor® GAS-bla ME-180 cell line is responsive to IFN-γ and can be used to probe the JAK/STAT signaling pathway. This cell line can be adapted for high-throughput screening of agonist or antagonist compound libraries. Candidate drugs can be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.

CellSensor™ SIE-bla THP-1 Cell Line

The CellSensor® SIE-bla THP-1 cell line contains a beta-lactamase reporter gene under control of the Sis Inducible Element (SIE), stably integrated into THP-1 cells. To construct this cell line, the SIE-bla construct was transduced into THP-1 cells by lentivirus. Flow cytometry was used to isolate cells responsive to Interferon Gamma (IFNγ). This cell line is validated for DMSO tolerance, cell number, stimulation time, substrate loading time, as well as Z´ and EC50 concentrations for IFN&gamma. The CellSensor® SIE-bla THP-1 cell line is responsive to IFNγ and can be used to analyze the JAK/STAT pathway using the GeneBLAzer® Loading Substrates. Academic and non-profit customers, please inquire for special pricing.