Learn More

We provide you with interactive HPLC introduction documents for your self-study. Our HPLC familiarization documents cover basic introduction and operation of our HPLC instruments, ensuring you have a positive start-up experience.

Discover our range of onsite and digital training programs and stay up to date with our latest HPLC information. Our experienced trainers create eLearning content and present live or remote training in an efficient and engaging way.

Our HPLC and UHPLC instruments offer uncompromised performance, robustness, and ease of use. A key element is the accessibility of system components for simple maintenance and replacement procedures that are described in the operating manuals.

Our repair-on-demand or flexible service plan options are provided on-site, via depot repair, or with an on-site service engineer. On average, service plans provide 50% faster response time and 30% less downtime compared to customers without a service plan.

Our portfolio of innovative and dependable liquid chromatography (LC) instruments includes analytical HPLC and UHPLC systems to handle any separation challenge from simple to complex samples; application-specific HPLC and UHPLC systems for applications such as 2D-LC and dual LC; and nano-,...

HPLC and UHPLC instruments are complex systems composed of multiple components. Are you curious to see what our Vanquish HPLC/UHPLC systems look like on the inside? We've designed our 3D product tours and virtual demos to help you explore these systems in a self-guided manner.

Our Thermo Scientific UltiMate 3000 HPLC and UHPLC Systems feature customizable configurations and provide you with the analytical flexibility you need for multiple applications, ranging from method development to routine analysis., Browse our complete Ultimate 3000 LC system portfolio below.

Running into issues with your HPLC or UHPLC analysis? We provide online LC troubleshooting help with a list of symptoms, root causes and solutions for common UHPLC and HPLC problems. Troubleshoot common LC issues › Our HPLC Troubleshooting Guide App offers more comprehensive solutions to common...

This whiteboard video provides a brief history of chromatography, and explains the fundamental principles behind HPLC and UHPLC. It also describes the essential components, or modules, of a chromatography system., Do you have questions about how HPLC instruments work?

Find manuals and guides for Thermo Scientific UltiMate 3000 UHPLC and HPLC systems and components., Robust, reliable and with unmatched retention time precision. Learn how our award-winning Thermo Scientific Vanquish HPLC and UHPLC instruments can help you unlock substantial productivity gains and...

Choosing the right HPLC system for your separation needs can be overwhelming. Build your ideal HPLC or UHPLC system with our step-by-step configurator, including descriptions and comparison tables, to help you choose what’s right for your needs.

Separate even the most complex samples with confidence with an extensive portfolio of innovative, reliable and easy-to-use Thermo Scientific HPLC and UHPLC systems. These systems and their associated software and related products help ensure that you have confidence in your data and your analyses...

A fully operational HPLC system combines hardware, software, and consumables, each essential in successful analysis. Here is a breakdown of each component and the function:, The heart of an HPLC system. Keeps the mobile phase moving through the HPLC system. Learn more ›, The hands of an HPLC system.

Biotherapeutic proteins such as monoclonal antibodies (mAbs) are far more heterogeneous than small-molecule drugs. The presence of the charged state can significantly impact the structure, stability, binding affinity, and efficacy of the biotherapeutic drug.

High-performance liquid chromatography (HPLC) is a broad analytical chemistry technique used to separate compounds in a chemical mixture. These separations utilize the pressure-driven flow of a mobile phase through a column packed with a stationary phase.