Sort By

MAP3K14 (NIK) Recombinant Human Protein

MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes.

MAP3K14 Polyclonal Antibody (Invitrogen™)

NIK Polyclonal Antibody for IF, ICC, IHC (P)

CellSensor™ AP-1-bla ME-180 Cell Line

The CellSensor® AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into ME-180 cells. The cell line was created through FACS sorting of cells responsive to stimulation of the AP-1 pathway with Epidermal Growth Factor (EGF). This cell line was validated for DMSO tolerance, stimulant incubation time, substrate loading conditions, Z' and EC50 concentration of Epidermal Growth Factor. The AP-1-bla ME-180 Cell Line responds to agonist treatment as expected from the literature and can be adapted for high-throughput screening for agonists or antagonists of the AP-1 pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.

NIK Antibody (3H31L48), ABfinity™ Rabbit Monoclonal (Invitrogen™)

NIK Monoclonal Antibody for Western Blot, IF, ICC

NIK Polyclonal Antibody (Invitrogen™)

NIK Polyclonal Antibody for Western Blot

NIK Polyclonal Antibody (Invitrogen™)

NIK Polyclonal Antibody for Western Blot, IHC

HGK Polyclonal Antibody (Invitrogen™)

HGK Polyclonal Antibody for Western Blot

NIK Polyclonal Antibody (Invitrogen™)

NIK Polyclonal Antibody for Western Blot

NIK Polyclonal Antibody (Invitrogen™)

NIK Polyclonal Antibody for Western Blot

NIK Polyclonal Antibody (Invitrogen™)

NIK Polyclonal Antibody for Western Blot, IF, ICC