Products

MAbPac™ Reversed Phase HPLC Columns Thermo Scientific™

Use the new Thermo Scientific™ MAbPac™ Reversed Phase columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized for high resolution separations.

MAbPac™ SCX-10 HPLC Columns Thermo Scientific™

Use Thermo Scientific™ MAbPac™ SCX-10 LC Columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

MAbPac™ SEC-1 Size Exclusion Chromatography HPLC Columns Thermo Scientific™

Use Thermo Scientific™ MAbPac™ SEC-1 Size Exclusion Chromatography HPLC Columns for high-resolution separation of monoclonal antibody (mAb) analysis, including the monomers, aggregates and Fab and Fc fragments resulting from proteolysis. These size-exclusion chromatography (SEC) columns provide superior performance, even under nondenaturing conditions, and in high- and low-salt mobile phases and volatile eluents.

MAbPac™ Protein A Antibody Analysis and Purification HPLC Column, 12 μm, 4 mm x 35 mm Thermo Scientific™

Run fast, accurate titer analysis of monoclonal antibodies (mAbs) in harvest cell cultures with the Thermo Scientific™ MAbPac™ Protein A LC Columns. This column provides high throughput and accurate analyses through a combination of low backpressure and high efficiency. Its unique format makes automation of loading, binding, elution and collection using biocompatible systems quick and easy. A nonporous, polymeric resin with a hydrophobic divinylbenzene core and a hydrophilic surface optimized for affinity separation makes this column rugged and reproducible.

MAbPac™ HIC-10 HPLC Column Thermo Scientific™

Designed for separation of monoclonal antibodies (mAbs) and related biologics by hydrophobic interaction, the Thermo Scientific™ MAbPac™ HIC-10 LC column is a high resolution silica column. The MAbPac HIC-10 column's unique chemistry provides high resolution, excellent biocompatibility, and selectivity that is different from other HIC columns on the market.

MAbPac™ HIC-20 HPLC Columns Thermo Scientific™

Use the Thermo Scientific™ MAbPac™ HIC-20 HPLC column for separation of monoclonal antibodies (mAbs), mAb fragments and oxidized variants by hydrophobic interaction chromatography (HIC). The unique chemistry of this silica column offers high resolution and excellent selectivity. The advanced surface bonding technology provides excellent chemical stability, high resolution, and unique selectivity optimized for mAbs and different from other HIC phases.

MAbPac™ HIC-Butyl HPLC Columns Thermo Scientific™

Use the Thermo Scientific™ MAbPac™ HIC-Butyl HPLC columns to separate monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs). This column is based on hydrophilic, nonporous, 5µm polymer particles functionalized with butyl groups. The column's hydrophilic resin provides excellent biocompatibility and low carryover, while the optimal density of the butyl groups provides high resolution separation.

MAbPac™ SCX-10 RS Monoclonal Antibody Analysis Column, 5µm Thermo Scientific™

For high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants, use Thermo Scientific™ MAbPac™ SCX-10 RS Monoclonal Antibody Analysis Columns, 5µm. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

MAbPac™ Capillary Reversed Phase HPLC Column

Use the Thermo Scientific™ MAbPac™ Capillary Reversed Phase HPLC Column high sensitivity HPLC or LC/MS characterization of intact proteins in top-down proteomics applications where sample amount is critically limited. This versatile column can be used for peptide-mapping characterization where the capillary format balances sensitivity with throughput. Additional applications are monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over.

pH Gradient Buffers Thermo Scientific™

Obtain fast and highly robust, reproducible HPLC gradients using Thermo Scientific™ CX-1 pH Gradient Buffers. Simple to optimize and easily automated, these buffers are applicable for HPLC separation of the majority of monoclonal antibody (mAb) biotherapeutics drugs. CX-1 pH Gradient Buffers are ready to use with existing HPLC columns without the need to formulate mobile phases. The CX-1 buffers save time in method development, facilitate method transfer to QA/QC for a wide range of mAb charge variants through a generic HPLC-based approach to mAb characterization, and do not require time-consuming mobile phase adjustments.

EASY-Spray™ HPLC Columns Thermo Scientific™

Ensure robust nano and capillary flow into your LC-MS using Thermo Scientific™ EASY-Spray™ HPLC Columns. The integrated column/emitter design eliminates dead volume and is temperature-controlled for maximum reliability and performance. Rigorously tested to ensure maximum quality, these columns deliver maximum simplicity and ease-of-use. The capillary flow HPLC columns provide sensitive protein, peptide, and monoclonal antibody (mAb) separation. They give proteomics researchers more than ever before: more throughput, more sensitivity, more separation power and more ease of use.

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