Learn More Carrier Protein Immunogens and Adjuvants
We offer keyhole limpet hemocyanin (KLH) and other carrier proteins to conjugate peptides and haptens through sulfhydryl, amine or carboxyl groups to elicit the production of specific antibodies against almost any molecule. We also offer adjuvants for effective immunization.
Our array of Thermo Scientific Pierce Custom Antibody Services includes a customizable option for mouse immunization, serum-collection and titer analysis for mouse polyclonal antibody production. Custom Antibody Request, Custom mouse antibodies Track and customize project Full service integration,...
Learn More PEGylation Reagents (PEG Labeling)
We offer activated linear and branched derivatives of polyethylene glycol (PEG) for pegylation and the PEG-modification of peptides and proteins via primary amines and sulfhydryl groups. These reagents are typically used to increase solubility, prolong stability, and reduce immunogenicity.
Our comprehensive array of Thermo Scientific Pierce custom antibody services includes a customizable option for rat immunization, serum-collection, and titer analysis for rat antibody production, plus extension possibilities.
Our comprehensive array of Thermo Scientific Pierce custom antibody services includes a customizable option for chicken immunization, egg-collection and titer analysis for chicken antibody production, plus several extension possibilities.
Learn More Peptide Design
Introduction peptide design Peptide length Peptide solubility Peptide composition Phosphorylation Amidation/acetylation Enantiomers Isotopes Cyclization Spacers Dyes Common dyes used in peptide modifications Immunogens Unnatural amino acids, Peptide Libraries and Services Standard Peptide Custom...
The ability of animal immune systems to produce antibodies capable of binding specifically to antigens can be harnessed to manufacture probes for detection of molecules of interest in a variety of research and diagnostic applications.
PEG is the common abbreviation for polyethylene glycol – or, more properly, poly(ethylene glycol) – which refers to a chemical compound composed of repeating ethylene glycol units. Synthesis of PEG, Depending on how one chooses to define the constituent monomer or parent molecule (as ethylene...
Learn More Antibody Production
Antibody production refers to the steps leading up to antibody generation and involves preparation of antigen samples and their safe injection into laboratory or farm animals to evoke high expression levels of antigen-specific antibodies in the serum, which can then be recovered from the animal.
Learn More Antibody Production (Immunogen Preparation)
The production of specific antibody probes is a relatively straightforward process involving immunization of animals and reliance upon their immune systems to levy responses that result in biosynthesis of antibodies against the injected molecule.
In 2009, we updated and streamlined the structure of our immunogenic carrier protein products and conjugation kits. In doing so, we performed a number of experiments designed to validate and demonstrate the quality, properties, differences and uses of these reagents.
Learn More Host Cell Protein Analysis
Host cell proteins (HCPs) are low-level, process-related protein impurities in drug products derived from the host organism during biotherapeutic manufacturing. During expression of a recombinant protein drug, host cell systems can express many endogenous proteins.
Learn More Protein Crosslinking
Crosslinkers contain reactive ends to specific functional groups, such as primary amines and sulfhydryls on proteins and antibodies, enabling the covalent joining of or two or more biomolecules. Homobifunctional crosslinkers have the same reactive chemistry at both ends and heterobifunctional have...
Learn More Peptides and Proteins
We offer a wide range of peptides and recombinant proteins for use in your experiments. Our custom peptides and peptide libraries are available with flexible modification, conjugation, and isotopic labeling options.
Learn More Antibodies and Proteins Information
Learn about methods and technologies for preparing and using antibodies and recombinant proteins in protein analysis techniques. Understand how specific primary and secondary antibodies are produced, screened, purified, and modified to enable their use in a myriad of protein detection...