Learn More Protein HPLC Columns
High resolution and high efficiency set these columns apart. For excellent analytical characterization of proteins, we offer a full range of Thermo Scientific affinity, ion exchange, reversed phase, hydrophobic interaction, and size exclusion columns for your protein sample.
Size exclusion chromatography (SEC) is a major mode of HPLC that employs porous particles in the column to separate molecules by virtue of their size in solution. SEC is generally used to separate biological molecules, to determine molecular weight distributions of proteins and peptides, as well as...
Learn More Acclaim HPLC Columns
Thermo Scientific Acclaim HPLC Columns have a smaller pore size and higher surface area to deliver the high resolution you need for high-efficiency separations. Choose from a broad variety of functional groups including: Thermo Fisher Scientific designed and manufactured all Acclaim columns to tight...
Learn More Bio LC Columns
Get high resolution, high efficiency separations of biological samples. Our unique column chemistries for biological samples have been specifically designed for the separation of proteins, peptides, monoclonal antibodies, carbohydrates, nucleic acids, and more.
Learn More Monoclonal Antibody HPLC Columns
Extensive development of protein and monoclonal antibody (mAb) therapeutics currently underway requires innovative and efficient tools that characterize and quantify structural variants and modifications, monitor product stability and demonstrate safety and efficacy.
Learn More HPLC and UHPLC Columns
Need a reliable column? With over 40 years as a leader in LC column technology, you can rely on the quality of Thermo Scientific™ HPLC and UHPLC columns. Our extensive family of products offers a variety of particle sizes and column designs to meet all separation needs, including improved...
Learn More Oligonucleotide HPLC Columns
These columns are used in HPLC and UHPLC experiments. What sets Thermo Scientific DNAPac columns apart from the rest is their ability to provide exceptionally high resolution separations of nucleic acids (+1 and -1), including isomers, which is not possible with reversed phase columns. The larger i.
Learn More Capillary HPLC Columns
Use these capillary reversed phase (RP) columns for high-sensitivity HPLC-UV or LC/MS characterization of intact proteins in top-down proteomics applications where sample amount is critical. Intact proteins in top-down proteomics applications Monoclonal antibodies (mAbs), fragments, variants,...
Learn More Accucore HPLC and UHPLC Columns
Based on Core Enhanced Technology, Thermo Scientific Accucore HPLC and UHPLC columns provide ultimate core performance, allowing you to maximize your investment. Solid core particles make for fast separations with superb resolution.
Learn More Glycan HPLC Columns
Mixed-mode Thermo Scientific GlycanPac columns provide uniquely exceptional high resolution separation of neutral and charged glycans. In addition, we offer traditional amide-HILIC columns for the separation of neutral glycans, and ligand exchange columns for the purification and isolation of...
Learn More Reversed Phase HPLC Columns
Need to maximize your productivity and flexibility in method development? Thermo Scientific reversed phase LC columns are available in an array of chemistries to optimize separations and provide enhanced retention or changes in elution order.
Learn More Low Flow HPLC Columns
Low-flow chromatography is ideal when detailed sample information is required from small sample volumes, especially for bottom-up and top-down proteomics research. Compared with analytical flow LC-MS (>100 µL/min), the signal with low-flow (<100 µL/min) can be many times higher.
Learn More ProPac Elite WCX 5µm LC Columns
Address your challenging charge variant separations by using the Thermo Scientific ProPac Elite WCX5µmLCcolumns. Thisweak cation exchange (WCX) column builds onpopular ProPac WCX-10 columns by reducing the particle size of the nonporous resin from 10μm to 5μm, thus providing even faster and higher...
Learn More HPLC and UHPLC Related Products
Viper and nanoViper Fingertight Fittings, tubing, kits, and accessories allow you to quickly connect HPLC modules, valves, and columns. They enable leak-free connections that improve chromatographic results by minimizing dead volume.
Regulatory bodies typically impose a limit on the acceptable degree of protein aggregation that a biotherapeutic may exhibit, and therefore the confirmation of protein aggregate levels is vital throughout the drug development and production process.