Learn More

Tandem mass tags (TMT) are robust and efficient systems for multiplex, relative protein quantitation of up to 18 samples, derived from cells, tissues, or biological fluids. All mass tagging reagents within a label reagent set have the same nominal mass (i.e.

Describe how you will use Thermo Scientific tandem mass tag (including amine-, sulfhydryl-, or carbonyl-reactive) labeling reagents and Thermo Scientific mass spectrometry (MS) reagents in your research, and you could receive one of two awards that provide up to $11,000 worth of these reagents, free...

Proteomics techniques are evolving to become a highly sensitive, quantitative, and high-throughput approach to analyzing global protein dynamics within a cell, tissue or an organism. In the past decade, critical advances have been made across the entire proteomics workflow, most notably the...

Mass spectrometry can detect very low analyte concentrations in complex mixtures. It can be quantitative with the use of peptide labels or standards that are concomitantly analyzed with the sample and act as a reference point for both relative or absolute analyte quantitation, respectively.

Find relevant citations from peer-reviewed journals where specific research results were generated using Thermo Scientific Tandem Mass Tag (TMT) reagents. Either browse, search, or sort the citations, Learn more about TMT reagents and kits, No records were found matching your criteria, Overview of...

View all What is the difference between Relative and Absolute Quantitation? Which type of quantitation is used for proteomic samples? What is the main purpose of Tandem Mass Tag (TMT) reagents? What type of mass spectrometer can I use for Tandem Mass Tag (TMT) analysis?

Released glycans have no chromophore and a poor response with conventional UV detection. They can be labeled with fluorescent and/or mass spectrometric tags prior to high sensitivity analysis by fluorescence detection, typically using 2-aminobenzamide (2-AB).

Proper sample preparation is a critical step in the proteomics workflow because the quality and reproducibility of these steps significantly impact the separation and identification capabilities of mass spectrometers.

Optimize your experiments to get the best results. We’ve compiled a detailed knowledge base of the top tips and tricks to meet your research needs., View the relevant questions below:, Browse our FAQ database for more information ›, Having problems with your experiment?

On this webpage you will find a collection of valuable tools to help improve your mass spectrometry results including the handbooks, application specific whitepapers and technical notes, late-breaking posters, and helpful webinars.

For Research Use Only. Not for use in diagnostic procedures., View all If I’m not using zoom scan, do I still need to calibrate it? What are the differences between the various scan types? What does a proper cal mix look like, and what should my NL be?

(See a list of the products featured in this article.), The protein composition of a cell at any given time defines the cell’s health and function. A specific protein’s abundance, localization, and lifetime has traditionally been studied with antibodies or other highly selective tags.

Carol L. Nilsson, Ph.D.1; John C. Rogers, Ph.D.; Waldemar Priebe, Ph.D.2; Roslyn Dillon, Ph.D.1; Bryan Krastins, Ph.D.3; David Sarracino, Ph.D.3; Arugadoss Devakumar, Ph.D.1; Barbara Kaboord, Ph.D.; Michael Major, Ph.D.; Michael M. Rosenblatt, Ph.D.; Mary Lopez, Ph.D.3; Frederick F. Lang, Jr, Ph.D.

We are dedicated to your success. Get back on track. View our expert recommendations for commonly encountered problem scenarios., View the relevant questions below:, Browse our FAQ database for more information ›, Having problems with your experiment?

Ryan D. Bomgarden, Ph.D.; Eric L. Hommema, Ph.D.; Rosa I. Viner, Ph.D.1; Zhe Qu, Ph.D.2; Zezong Gu, Ph.D.2; John Rogers, Ph.D., S-nitrosylation is a post-translational modification (PTM) that regulates numerous processes, including cellular proliferation, apoptosis, smooth muscle relaxation,...