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iPrPAC-dG Phosphoramidite, standard grade, serum vial bottle (Thermo Scientific™)

iPrPAC-dG CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Isopropylphenoxyacetyl (iPrPAC) base protection, for use in oligonucleotide synthesis. The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions. Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05M potassium carbonate in methanol. The "Standard Grade" marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.

• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isopropylphenoxyacetyl-2'-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C51H60N7O9P
• Base—dG
• Base Protection—iPrPAC
• Formula weight—946.05 g/mol
• CAS number—150065-82-0
• HPLC Purity—≥98.0%
• 31P NMR Purity—≥98.0%