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CD3D & CD3E Recombinant Mouse Protein, hIgG1-Fc & hIgG1-Fc.His tag

CD3 Antigen delta and CD3 Antigen epsilon Heterodimer (CD3D & CD3E), recombinant mouse protein is supplied as a lyophilized powder.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ala 105) of mouse CD3D (P04235) fused to the C-terminal flag-tagged Fc region of human IgG1 at the C-terminus, constructed the plasmid 1; a DNA sequence encoding the extracellular domain (Met 1-Asp 108) of mouse CD3E (P22646) fused to the C-terminal His-tagged Fc region of human IgG1 at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the mouse CD3D/CD3E heterodimer was purified.

Activity: This recombinant protein has not been tested.

Formulation: 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by SINO Biological.

BST1 (CD157) Recombinant Human Protein, His tag

Bone marrow stromal cell antigen 1 (BST1/CD157), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the human BST1 (NP_004325.2), Met 1-Lys 292, fused to a polyhistidine tag at the C-terminus.

Activity: This recombinant protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

CD200R1 Recombinant Human Protein, His tag

Cluster of Differentiation 200 receptor 1 (CD200R1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, studying protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Leu 266) of human CD200R1 (AAI43394.1) fused to a polyhistidine tag at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA . Immobilized human CD200R1 at 1 µg/ml(100 µl/well) can bind human CD200 with a linear range of 0.12-16 ng/ml.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

FCGR3A, 176 Phe/Val Recombinant Human Protein, His Tag

Fc fragment of IgG, low affinity IIIa, receptor (FCGR3A/CD16a), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1- Gln 208) of human FCGR3A (P08637-1), (176 Phe/Val), to fused to a polyhistidine tag at the C-terminus.

Activity: This recombinant protein has not been tested.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

PVRL3 Recombinant Human Protein, His Tag

Poliovirus receptor-related 3 (PVRL3), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of human PVRL3 (NP_056295.1) (Met 1-Asp 400) fused to the polyhistidine tag at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA
.

1. Immobilized recombinant human PVRL3 at 1 µg/ml (100 µl/well) can bind biotinylated PVRL1/Nectin 1 with a linear range of 6.4-800 ng/ml
.

2. Immobilized recombinant human PVRL3 at 1 µg/ml (100 µl/well) can bind PVRL1/Nectin 1-Fc chimera with a linear range of 0.156-5 ng/ml.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

CEACAM6 (CD66C) Recombinant Human Protein, His Tag

Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the human CEACAM6 (NP_002474.3) (Met 1-Gly 320) fused to a polyhistidine tag was expressed at the C-terminus.

Activity:1. Measured by its binding ability in a functional ELISA.
2. Immobilized human CEACAM6-His (Cat:10823-H08H) at 10 µg/ml (100 µl/well) can bind biotinylated human CEACAM8-His. The EC50 of biotinylated human CEACAM8-His is 0.17 µg/ml.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

ICOSLG (ICOSL) Recombinant Human Protein, His Tag

Inducible T-cell co-stimulator ligand (ICOSLG), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the human ICOSLG (NP_056074.1) extracellular domain (Met 1-Ser 258) fused to the polyhistidine tag at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA
. Immobilized human ICOSLG at 1 µg/ml (100 µl/well) can bind human ICOS with a linear range of 1.6-200 ng/ml.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

CD14 Recombinant Human Protein, hIgG1-Fc tag

Cluster of Differentiation 14 (CD14), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the the mature form of the extracellular domain (Thr 20-Cys 352) of human CD14 (NP_000582.1) fused to the Fc region of human IgG1 at the N-terminus.

Activity: This recombinant protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

FCGR3A (CD16a), 158 Phe/Val Recombinant Human Protein, His.AVI Tag, Biotinylated

Fc gamma receptor III-a (FCGR3A/CD16a), recombinant human protein is supplied as a frozen format. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gln 208) of human FCGR3A (P08637-1), containing the 176 Phe/Val mutation, fused to a polyhistidine and AVI tags at the C-terminus. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.

Activity: Measured by its ability to bind recombinant human IgG1 in a functional ELISA.

Formulation: PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 10% glycerol, and 0.02% Tween 80.

Reconstitution: No reconstitution is needed. Store aliquots under sterile conditions at -80°C. Thaw protein on ice before use and avoid repeated freeze-thaw cycles.

This protein is manufactured by Sino Biological Inc.

CEACAM-5 Recombinant Human Protein, His Tag

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Protein (CEACAM5), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the mature form of human CEACAM5 (NP_004354.2) (Met 1-Ala 685) fused to a polyhistidine tag at the C-terminus.

Activity: The activity of this protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

This protein is manufactured by Sino Biological Inc.

CD274 (PDL1) Recombinant Human Protein, hIgG1-Fc tag

CD274 molecule (CD274), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the N-terminal segment (Met 1-Thr 239) of the extracellular domain of human CD274 (NP_054862.1) fused to the Fc region of human IgG1 at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA
. Immobilized human PDCD1/PD1 at 10 µg/ml (100 µg/well) can bind recombinant human CD274/PDL1-Fc chimera with a linear range of 0.02-0.4 µg/ml
.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

SIRPA Recombinant Human Protein, His Tag

Signal-Regulatory Protein Alpha (SIRPA), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the human SIRPA (NP_542970.1) extracellular domain (Met 1-Arg 370) fused to a polyhistidine tag at the C-terminus.

Activity: The activity of this protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

This protein is manufactured by Sino Biological Inc.

CD33 Recombinant Mouse Protein, His tag

Cluster of Differentiation 33 (CD33), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of mouse CD33 (Q63994-1) (Met 1-Glu 240) fused to a polyhistidine tag at the C-terminus.

Activity: The activity of this protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

This protein is manufactured by Sino Biological Inc.

CD200 Recombinant Mouse Protein, His tag

Cluster of Differentiation 200 (CD200), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, studying protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 232) of mouse CD200 (NP_001076017.1) fused to a polyhistidine tag at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA . Immobilized recombinant mouse CD200 at 1 µg/ml(100 µl/well) can bind mouse CD200R1-Fc with a linear range of 1.5-200 ng/ml.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

CDH1 Recombinant Human Protein, His Tag

Manufactured by Sino Biological (China); Distributed by Life Technologies.

Cadherin 1, type 1, E-cadherin (epithelial) (CDH1) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications.

This recombinant protein is expressed from a DNA sequence encoding the extracellular domain of human CDH1 precusor (NP_004351.1) (Met 1-Ile 707) fused to the polyhistidine tag at the C-terminus.

N-terminal Sequence Analysis: Gln 23 & Asp 155.

Activity: measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast adenocarcinoma cells . When cells are added to CDH1/ECAD coated plates (1.5 µg/mL, 100 µL/well), approximately 60 %-80 % will adhere specifically .

Formulation: lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% mannitol, 5% trehalose, 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: expires one year from date of receipt when stored as instructed.

Background
Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is the classical cadherin molecule and contains five cadherin domains of ~110 aa each in the extracellular domain. E-Cad is expressed in the non-neural epithelial tissues as disulfide-linked homodimer, and plays a key role in the organization and integrity of most epithelial tissues, cell differentiation and tissue development. CDH1 interacts directly, via the cytoplasmic domain, with CTNNB1 or JUP to form the PSEN1/cadherin/catenin adhesion complex which connects to the actin skeleton through the actin binding of alpha-catenin.

You may also be interested in the following CDH1 products:
Primary Antibodies
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