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Human EGF Recombinant Protein, eBioscience™ Invitrogen™

Human EGF Recombinant Protein for Ctrl

EGF Recombinant Human Protein Gibco™

EGF is a bioactive protein intended for use in cell culture applications. EGF has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin.

Advantages of using our EGF:

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High-purity, recombinant, bioactive protein
Human EGF is one of our more than 250 available recombinant proteins. To help ensure growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human EGF specific activity is determined by the dose dependent proliferation of mouse BALB/3T3 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

GDNF Recombinant Human Protein Gibco™

Glial-Derived Neurotrophic Factor (GDNF) is a bioactive protein intended for use in cell culture applications. GDNF is mainly known for its affect on neurons, but it is also involved in other biological processes including kidney development.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Glial-Derived Neurotrophic Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Glial-Derived Neurotrophic Factor (GDNF) specific activity is determined by inducing neurite outgrowth on PC-12 cells in the presence of recombinant soluble GFR-α.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL20 Recombinant Human Protein Gibco™

Recombinant IL20 is a bioactive protein intended for use in cell culture applications. There are two heterodimeric receptor complexes for IL20. The first is composed of IL20 Ra and IL20 Rb. The second is composed of IL-22 R and IL20b. IL20 induces the proliferation of multipotential hematopoietic progenitor cells, directs the differentiation and expansion of keratinocytes, and promotes the release of proinflammatory mediators in keratinocytes and other cells expressing the IL20 receptor.

Mouse IL-15 Recombinant Protein, eBioscience™ Invitrogen™

Mouse IL-15 Recombinant Protein, eBioscience™

BMP-2 Recombinant Protein, eBioscience™ Invitrogen™

Human BMP-2 Recombinant Protein for Ctrl, FN

EPO Recombinant Human Protein Gibco™

Erythropoietin (EPO) is a bioactive protein intended for use in cell culture applications. Erythropoietin is a member of the EPO/TPO family. It regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Erythropoietin is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Erythropoietin (EPO) specific activity is determined by in vivo bioassay measuring dose-dependent increase in reticulocyte count with normocythaemic mice.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

TGFB2 Recombinant Human Protein Gibco™

Recombinant Human Transforming Growth Factor β 2 (TGFB2) is a bioactive protein intended for use in cell culture applications. TGFB2 binds the transforming growth factor-β receptor and plays a role in regulation of cell growth and proliferation. It may be involved in mesenchymal-epithelial cell interactions during development.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Transforming Growth Factor β 2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 2 (TGFB2) specific activity is determined by its ability to inhibit the mouse IL-4 dependent proliferation of mouse HT-2 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

RANTES Recombinant Human Protein Gibco™

Recombinant RANTES is a bioactive protein intended for use in cell culture applications. RANTES functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. RANTES is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.

Human IL-2 Recombinant Protein, eBioscience™ Invitrogen™

Human IL-2 Animal Free Recombinant Protein for Ctrl, FN

LEFTY-A Recombinant Human Protein Gibco™

Recombinant Human LEFTY-A is a bioactive protein intended for use in cell culture applications. LEFTY-A are TGF-β ligands that inhibit TGF-β signalling. LEFTY-A have been shown to induce mitogen activated protein kinase activity.

• High purity—no interference from other proteins or contaminants
• High biological activity—more results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human LEFTY-A is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to get a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human LEFTY-A specific activity is determined by the dose dependent ability to inhibit BMP4induction of alkaline phosphatase production in the MC-3T3-E1 cell line.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Human IL-12 p70 Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Human IL-12 p70 Carrier-Free Recombinant Protein, eBioscience™

BLC Recombinant Mouse Protein Gibco™

Recombinant BLC is a bioactive protein intended for use in cell culture applications. BLC preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.

Porcine IL-6 Recombinant Protein Invitrogen™

Porcine IL-6 Recombinant Protein for Western Blot, IP, ELISA, Ctrl

FGF10 Recombinant Human Protein Gibco™

Recombinant human FGF10 is a bioactive protein intended for use in cell culture applications. FGF10 is a member of the FGF family of growth factors and is involved in wound healing.

Sonic Hedgehog C25II Recombinant Mouse Protein Gibco™

Recombinant Sonic Hedgehog C25II is a bioactive protein intended for use in cell culture applications. Sonic Hedgehog is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites.

LIF Recombinant Human Protein Gibco™

Recombinant human leukemia inhibitory factor (LIF) is a bioactive protein intended for use in cell culture applications. LIF is a cytokine that induces macrophage differentiation. LIF, in conjunction with BMP2, acts on primary fetal neural progenitor cells to induce astrocytes.

• High purity—minimizes interference from other proteins or contaminants
• High biological activity—more results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant human LIF is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human LIF-specific activity is determined by measuring the LIF dose-dependent proliferation of Human TF-1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

MIP-3-beta Recombinant Human Protein Gibco™

Recombinant MIP-3-beta is a bioactive protein intended for use in cell culture applications. MIP-3α (Macrophage inflammatory protein-3β) is a chemokine and is also known as CCL19.

IL17 Recombinant Mouse Protein Gibco™

Recombinant IL17 is a bioactive protein intended for use in cell culture applications. IL17 stimulates epithelial, endothelial or fibroblastic cells to secrete IL-6, IL-8 and G-CSF. IL17 also increases the expression of ICAM-1 in fibroblasts.

TGFB3 Recombinant Human Protein Gibco™

Recombinant Human Transforming Growth Factor β 3 (TGFB3) is a bioactive protein intended for use in cell culture applications. TGFB3 is involved in epithelial and endothelial cell proliferation and differentiation during development.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Transforming Growth Factor β 3 is one of more than 250 Gibco® recombinant proteins available from Life Technologies. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 3 (TGFB3) specific activity is determined in a toxicity assay using WHO Standard 98/608 for direct comparison.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IGF1 Recombinant Human Protein Gibco™

Recombinant Human Insulin-like Growth Factor 1 (IGF1) is a bioactive protein intended for use in cell culture applications. IGF1 binds its receptor, IGF1R, activating several signaling pathways. IGF1 has been shown to be involved in proliferation, differentiation, survival, growth, apoptosis and regeneration. This is the 100 microgram size.

• High purity—Minimizes interference from other proteins or contaminants
• High biological activity—More results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Insulin-like Growth Factor 1 (IGF1) is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Insulin-like Growth Factor 1 (IGF1) specific activity is determined by its ability to stimulate the proliferation of mouse FDC-P1 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Human IL-1 beta Recombinant Protein, eBioscience™ Invitrogen™

Human IL-1 beta Recombinant Protein for Ctrl

IFN-α Recombinant Rat Protein Gibco™

Recombinant IFN-α A is a bioacitve protein intended for use in cell culture applications. IFN-α is involved in antiviral and antiparasitic activitites.

EGF Recombinant Human Protein Solution Gibco™

EGF is a bioactive protein intended for use in cell culture applications. EGF has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin.

Advantages of using our EGF:

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High-purity, recombinant, bioactive protein
Human EGF is one of our more than 250 available recombinant proteins. To help ensure growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human EGF specific activity is determined by the dose dependent proliferation of mouse BALB/3T3 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

IL17 Recombinant Human Protein Gibco™

Recombinant IL17 is a bioactive protein intended for use in cell culture applications. IL17 stimulates epithelial, endothelial or fibroblastic cells to secrete IL-6, IL-8 and G-CSF. IL17 also increases the expression of ICAM-1 in fibroblasts.

Mouse IL-15/IL-15R Complex Recombinant Protein, eBioscience™ Invitrogen™

Mouse IL-15/IL-15R Complex Recombinant Protein, eBioscience™

Mouse IL-21 Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Mouse IL-21 Carrier-Free Recombinant Protein, eBioscience™

Vaccinia Virus B18R Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Vaccinia Virus B18R Carrier-Free Recombinant Protein for Ctrl, FN

Mouse IL-17A Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Mouse IL-17A Carrier-Free Recombinant Protein, eBioscience™

IL6 Recombinant Mouse Protein Gibco™

Recombinant Mouse Interleukin 6 (IL6) is a bioactive protein intended for use in cell culture applications. IL6 is a pleiotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Mouse Interleukin 6 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Mouse Interleukin 6 (IL6) specific activity is determined by the dose dependent proliferation of mouse B9 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

VEGF Recombinant Mouse Protein Gibco™

Recombinant Mouse Vascular Endothelial Cell Growth Factor (VEGF) is a bioactive protein intended for use in cell culture applications. VEGF exerts angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. VEGF has also been shown to be chemotactic for monocytes and osteoblasts.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Mouse Vascular Endothelial Cell Growth Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Mouse Vascular Endothelial Cell Growth Factor (VEGF) specific activity is determined by the dose dependent proliferation of human umbilical vein cells (HUVEC).

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

FGF19 Recombinant Human Protein Gibco™

Recombinant human FGF19 is a bioactive protein intended for use in cell culture applications. FGF19 is a member of the FGF family of proteins.

IL23 Recombinant Human Protein Gibco™

Recombinant Human IL23 is a bioactive protein intended for use in cell culture applications. IL23 is important in the inflammatory response. IL23 induces the secretion of IFN-γ, and stimulates the proliferation of Human T cells. Recombinant Human IL23 is one of the many Gibco® recombinant bioactive proteins available from Life Technologies. This is the 100 microgram size.

High purity—minimal interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human IL23 is one of more than 250 Gibco® recombinant proteins available from Life Technologies. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human IL23 specific activity is determined by measuring the IL23 dose dependent secretion of IL-17 from mouse splenocytes.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

We also offer a selection of growth factors for use in cell therapy applications through our Gibco® Cell Therapy Systems (CTS™) product line.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Related Links
See our selection of recombinant Gibco® growth factors.
Learn more about the Gibco® Cell Therapy Systems (CTS™) product line.

MIG Recombinant Human Protein Gibco™

Recombinant MIG is a bioactive protein intended for use in cell culture applications. MIG (Monokine induced by gamma-interferon) is a chemoattractant for activated T-cells.

Mouse IL-1 beta Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Mouse IL-1 beta Carrier-Free Recombinant Protein, eBioscience™

TNF (TNFa) Recombinant Human Protein

Tumor necrosis factor alpha (TNF-α) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications.

This recombinant protein is expressed from a DNA sequence encoding the soluble form of human TNF (NP_000585.2) (Val 77-Leu 233) retaining the initial Met at the N-terminus.

N-terminal Sequence Analysis: Met.

Activity: measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The EC50 for this effect is typically 25-200 pg/mL, corresponding to a specific activity of 5 x 106 to 4 x 107 units/ mg.

Formulation: lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% mannitol, 5% trehalose, 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: expires one year from date of receipt when stored as instructed.

Background
Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF1A, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF-α is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-α is primarily produced as a type I I transmembrane protein arranged in stable homotrimers, and a soluble trimeric form of TNF-α is released via proteolytic cleavage by the metalloprotease TACE/ ADAM17. Two receptors mediating the TNF-α function have been identified, the ubiquitous TNF RI from which most signaling are derived, and the hematopoietic cell-restricted TNF RII. Upon the TNF-α trimers binding, TNF receptors also form trimers, undergo a conformational change, and enable the adaptor protein TRADD to bind to the death domain, and thus initiates the signal pathways such as the NF-kB, Jak/STAT, and the MAPK pathways, as well as the death signaling. As a major mediator of apoptosis, inflammation and immunity, TNF-α has been implicated in the pathogenesis of a variety of human diseases including autoimmune diseases, insulin resistance, and cancer.

You may also be interested in the following TNF-α products:
ELISA Kits
Primary Antibodies
Pathway Analysis Kits

Human CD253 (TRAIL) Recombinant Protein, eBioscience™ Invitrogen™

Human CD253 (TRAIL) Recombinant Protein for Ctrl

Human IL-6 Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Human IL-6 Carrier-Free Recombinant Protein, eBioscience™

Human IL-3 Recombinant Protein, eBioscience™ Invitrogen™

Human IL-3 Animal Free Recombinant Protein for Ctrl, FN

Human KGF Recombinant Protein, eBioscience™ Invitrogen™

Human KGF Animal Free Recombinant Protein for Ctrl, FN

Mouse IL-10 Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Mouse IL-10 Carrier-Free Recombinant Protein, eBioscience™

Kallikrein 7 Recombinant Human Protein Gibco™

Recombinant Kallikrein 7 is a bioactive protein intended for use in cell culture applications. KLK7 is one of the Kallikreins, which are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis.

Mouse M-CSF Recombinant Protein, eBioscience™ Invitrogen™

Mouse M-CSF Recombinant Protein for Ctrl, FN

Human TNF beta Recombinant Protein, eBioscience™ Invitrogen™

Human TNF beta Recombinant Protein for Flow, ELISA, Ctrl

IL6 Recombinant Swine Protein Gibco™

Recombinant IL6 is a bioactive protein intended for use in cell culture applications. Recombinant human IL6 is intended for use in cell culture applications. IL6 is a pleotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response.

NGF Recombinant Human Protein

Nerve growth factor (NGF) recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications.

This recombinant protein was expressed from a DNA sequence encoding the mature form of human NGF (NP_002497.2) (Ser 122-Arg 239).

N-terminal Sequence Analysis: Ser 122

Activity: Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The EC50 for this effect is typically 0.4-1.0 ng/mL.

Formulation: Lyophilized in 50 mM NaAc, 150 mM NaCl, pH 5.5, 5% mannitol, 5% trehalose, 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

Background
As the first one of a series of neurotrophic factors, nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF, was demonstrated to exhibits the growth stimulating activity of NGF. β-NGF is a target-derived secreted homodimeric protein of two 120-amino acid mature polypeptides after proteolytic removal of the signal and pro peptide. NGF acts via at least two receptors on the surface of cells, TrkA and p75 receptors to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In additon to its neurotropic activities, studies indicated that NGF may also have an important role in the regulation of the immune system. The synthesis of β-NGF in astrocytes is enhanced by various other cytokines including IL-1, TNF-α, PDGF and TGF-β .Defects in β-NGF are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) characterized by degeneration of dorsal root and autonomic ganglion cells, as well as sensory and/or autonomic abnormalities.

You may also be interested in the following NGF products:
Enzyme & Protein Assays
Primary Antibodies
Gene Expression Assays

IL3 Recombinant Mouse Protein Gibco™

Recombinant Mouse Interleukin 3 (IL3) is a bioactive protein intended for use in cell culture applications. IL3 provides the cytokine connection between the immune system and the hematopoietic system. For example, IL3 supports the proliferation and development of almost all types of hematopoietic progenitor cells and can act as a chemoattractant for eosinophils.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Mouse Interleukin 3 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Mouse Interleukin 3 (IL3) specific activity is determined by the dose dependent proliferation of NFS-60 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL5 Recombinant Human Protein Gibco™

Recombinant Human Interleukin-5 (IL5) is a bioactive protein intended for use in cell culture applications. IL5 promotes the growth and differentiation of eosinophils.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin-5 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin-5 (IL5) specific activity is determined by measuring the IL5 dose dependent proliferation of TF-1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

SCF Recombinant Human Protein, Animal-Origin Free Gibco™

Recombinant Human Stem Cell Factor (SCF, c-kit Ligand) is a bioactive protein intended for use in cell culture applications. SCF is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Stem Cell Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Stem Cell Factor (SCF, c-kit Ligand) specific activity is determined by the dose dependent proliferation of human MO-7e cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

EGF Recombinant Human Protein, Animal-Origin Free Gibco™

Recombinant Human Epidermal Growth Factor (EGF) is a bioactive protein intended for use in cell culture applications. EGF has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Epidermal Growth Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Epidermal Growth Factor (EGF) specific activity is determined by the dose dependent proliferation of mouse BALB/3T3 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL13 Recombinant Mouse Protein Gibco™

Recombinant Mouse Interleukin 13 (IL13) is a bioactive protein intended for use in cell culture applications. IL13 down-regulates macrophage produced cytokines such as TNF-α, IL-1, IL-6, IL-8, and IL-12 in response to LPS challenge or IFN-γ. IL13 induces monocyte differentiation and also induces B cell differentiation and proliferation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Mouse Interleukin 13 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Mouse Interleukin 13 (IL13) specific activity is determined by the dose dependent proliferation of human TF-1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Mouse G-CSF Recombinant Protein, eBioscience™ Invitrogen™

Mouse G-CSF Recombinant Protein for Ctrl

Human IL-8 (CXCL8) (1-77) Recombinant Protein, eBioscience™ Invitrogen™

Human IL-8 (CXCL8) (1-77) Recombinant Protein for Ctrl, FN

IL10 Recombinant Human Protein Gibco™

Recombinant IL10 is a bioactive protein intended for use in cell culture applications. IL10 inhibits the synthesis of a number of cytokines, such as TNF-α, Il-1, and Il-6 from macrophages and Il-2, IFN-γ, and TNF-β from Th1 cells.

HGF Recombinant Human Protein Gibco™

Recombinant Human Hepatocyte Growth Factor (HGF) is a bioactive protein intended for use in cell culture applications. HGF plays a role in positive regulation of cell proliferation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Hepatocyte Growth Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Hepatocyte Growth Factor (HGF) specific activity is determined by the dose dependent proliferation of monkey 4MBr-5 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Mouse TSLP Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Mouse TSLP Carrier-Free Recombinant Protein for Ctrl, FN

TPO (Thrombopoietin), Recombinant Human Protein Gibco™

Recombinant Human Thrombopoietin (TPO) is a bioactive protein intended for use in cell culture applications. TPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, which is the product of the myeloproliferative leukemia virus oncogene. Recombinant Human Thrombopoeitin (TPO) is one of the many GIBCO® recombinant bioactive proteins available from Life Technologies. This is the 100 microgram size.

High purity—minimal interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—GIBCO® proteins bioassayed with GIBCO® media

High purity recombinant bioactive protein
Recombinant Human Thrombopoietin (TPO) is one of more than 250 GIBCO® recombinant proteins available from Life Technologies. To help ensure GIBCO® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High biological activity
In-house activity testing of Recombinant Human Thrombopoeitin (TPO) includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Thrombopoietin (TPO) specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Proven compatibility
GIBCO® proteins are bioassayed with GIBCO® media. Since 1962, GIBCO® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

We also offer a selection of growth factors for use in cell therapy applications through our GIBCO® Cell Therapy Systems (CTS™) product line.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Related links
See our selection of recombinant GIBCO® growth factors.
Learn more about the GIBCO® Cell Therapy Systems (CTS™) product line.

Mouse M-CSF Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Mouse M-CSF Carrier-Free Recombinant Protein for Ctrl, FN

IL7 Recombinant Human Protein Gibco™

Recombinant Human Interleukin 7 (IL7) is a bioactive protein intended for use in cell culture applications. IL7 stimulates the proliferation of pre-B and pro-B cells. IL7 also supports the maturation of megakaryocytes.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 7 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 7 (IL7) specific activity is determined by the dose dependent proliferation of human PBMCs.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Human TGF beta 3 Carrier-Free Recombinant Protein, eBioscience™ Invitrogen™

Human TGF beta 3 Carrier-Free Recombinant Protein for Neu, Ctrl, FN
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