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IL17A Recombinant Human Protein (Gibco™)

Recombinant IL17A is a bioactive protein intended for use in cell culture applications. IL17A is a proinflammatory cytokine that regulates the activities of NF-κB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).

SDF1B Recombinant Human Protein (Gibco™)

Recombinant SDF1B is a bioactive protein intended for use in cell culture applications. SDF1B is a small cytokine that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL-1.

IL21 Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 21 (IL21) is a bioactive protein intended for use in cell culture applications. IL21 R, is a type I cytokine receptor and is most closely related to IL-2 Rb and IL-4 Ra. The IL21/IL21 R interaction appears to play important roles in B and T-cell proliferation after antigen stimulation and NK cell maturation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 21 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 21 (IL21) specific activity is determined by the dose-dependent secretion of Interferon gamma by human natural killer lymphoma NK-92 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

MIP-3-alpha Recombinant Human Protein (Gibco™)

Recombinant MIP-3-alpha is a bioactive protein intended for use in cell culture applications. MIP-3-alpha (Macrophage inflammatory protein-3α) is a chemokine and is also known as CCL20.

BD1 Recombinant Human Protein (Gibco™)

Recombinant β-defensin 1 (BD1) is a bioactive recombinant protein intended for use in cell culture applications. BD1 is a member of the defensin family involved in defense against mibcrobes.

IL15 Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 15 (IL15) is a bioactive protein intended for use in cell culture applications. IL15 activity resembles some biological activities attributed to IL-2. IL15 induces proliferation of PMA activated peripheral blood mononuclear cells. IL15 also functions as a maturation factor for NK cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Interleukin 15 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 15 (IL15) specific activity is determined by measuring the dose-dependent proliferation of mouse CTLL-2 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL10 Recombinant Rat Protein (Gibco™)

Recombinant IL10 is a bioactive protein intended for use in cell culture applications. IL10 inhibits the synthesis of a number of cytokines, such as TNF-α, Il-1, and Il-6 from macrophages and Il-2, IFN-γ, and TNF-β from Th1 cells.

IL2 Recombinant Swine Protein (Gibco™)

Recombinant IL2 is a bioactive protein intended for use in cell culture applications. IL2 causes proliferation of T cells and is a central regulator of immune responses.

LEFTY-A Recombinant Human Protein (Gibco™)

Recombinant Human LEFTY-A is a bioactive protein intended for use in cell culture applications. LEFTY-A are TGF-β ligands that inhibit TGF-β signalling. LEFTY-A have been shown to induce mitogen activated protein kinase activity.

• High purity—no interference from other proteins or contaminants
• High biological activity—more results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human LEFTY-A is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to get a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human LEFTY-A specific activity is determined by the dose dependent ability to inhibit BMP4induction of alkaline phosphatase production in the MC-3T3-E1 cell line.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

Related links
See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

RANK Ligand Recombinant Human Protein (Gibco™)

Recombinant RANK Ligand (RANKL) is a bioactive protein intended for use in cell culture applications. RANKL is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. RANKL was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.

NAP-2 Recombinant Human Protein (Gibco™)

Recombinant NAP-2 is a bioactive protein intended for use in cell culture applications. NAP-2 (neutrophil activating protein-2) induces the uptake of calcium in neutrophils.

IL29 Recombinant Human Protein (Gibco™)

Recombinant IL29 is a bioactive protein intended for use in cell culture applications. IL29 is functionally similar to type I interferons, including antiviral activity and up-regulation of MHC class I antigen expression. IL29 signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor b (IL-10 Rb) and a novel IL-28 receptor a (IL-28 Ra, also known as IFN-γ R1). Binding to the receptor complex induces Jak kinase activation, as well as STAT1 and STAT2 tyrosine phosphorylation.

MCP-2 Recombinant Mouse Protein (Gibco™)

Recombinant MCP-2 is a bioactive protein intended for use in cell culture applications. MCP-2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils.

SDF1A Recombinant Mouse Protein (Gibco™)

Recombinant SDF1A is a bioactive protein intended for use in cell culture applications. SDF1A is a small cytokine that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL-1.

Oncostatin M Recombinant Human Protein (Gibco™)

Recombinant Human Oncostatin M (OSM) is a bioactive protein intended for use in cell culture applications. Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. Oncostatin M is a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Oncostatin M is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Oncostatin M (OSM) specific activity is determined by measuring the oncostatin M concentration dependent stimulation of proliferation of TF-1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.