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HGF Recombinant Human Protein (Gibco™)

Recombinant Human Hepatocyte Growth Factor (HGF) is a bioactive protein intended for use in cell culture applications. HGF plays a role in positive regulation of cell proliferation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Hepatocyte Growth Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Hepatocyte Growth Factor (HGF) specific activity is determined by the dose dependent proliferation of monkey 4MBr-5 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

SDF1A Recombinant Mouse Protein (Gibco™)

Recombinant SDF1A is a bioactive protein intended for use in cell culture applications. SDF1A is a small cytokine that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL-1.

M-CSF Recombinant Human Protein (Gibco™)

M-CSF (macrophage colony-stimulating factor) is a bioactive protein intended for use in cell culture applications. M-CSF induces proliferation and differentiation of hematopoietic stem cells into macrophages and growth and differentiation of monocytes.

Features of our recombinant human M-CSF:

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—proteins bioassayed with Gibco® media

High-purity, recombinant, bioactive protein
Human M-CSF is one of our more than 250 available recombinant proteins. To help ensure our growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of our recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human M-CSF specific activity is determined by measuring the dose dependent stimulation of proliferation of mouse M-NFS-60 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

IL1B Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 1, beta (IL1B) is a bioactive protein intended for use in cell culture applications. IL-1 is involved in a number of biological processes including the stimulation of T-helper cells, promotion proliferation and synthesis of immunoglobulins, and the activation of fibroblasts and NK cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 1, beta is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 1, beta (IL1B) specific activity is determined by the dose dependent proliferation of murine D10S cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

GM-CSF Recombinant Human Protein (Gibco™)

Recombinant Human Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) is a bioactive protein intended for use in cell culture applications. GM-CSF is involved in many biological responses including the growth and development of granulocyte and macrophage progenitor cells, stimulation and the initiation of differentiation of myeloblasts and monoblasts, and chemotaxis of eosinophils.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Granulocyte Macrophage Colony-Stimulating Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) specific activity is determined by the dose dependent proliferation of human TF-1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Activin R1b Recombinant Human Protein (Gibco™)

Recombinant Activin R1b is a bioactive protein intended for use in cell culture applications. Recombinant Activin Receptor 1B (ActivinR1B) is intended for use in cell culture applications. ActivinR1B is involved in a number of biological processes including growth and differentiation, cell proliferation, apoptosis, and embryonic cell fate.

BMP2 Recombinant Human Protein (Gibco™)

Recombinant Human Bone Morphogenetic Protein 2 (BMP2)is a bioactive protein intended for use in cell culture applications. BMP2is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. BMP2 acts as a disulfide-linked homodimer and induces bone and cartilage formation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Bone Morphogenetic Protein 2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Bone Morphogenetic Protein 2 (BMP2)specific activity is determined by the dose dependent induction of alkaline phosphatase in mouse chondrogenic cell line ATDC5.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

CXCL1 (CINC-1) Recombinant Rat Protein (Gibco™)

Recombinant CXCL1 (CINC-1) is a bioactive protein intended for use in cell culture applications. CXCL1 is a chemokine that induces the infiltration of neutrophils.

SCF (C-Kit Ligand) CTS™ Recombinant Human Protein (Gibco™)

Cell Therapy Systems CTS™ Recombinant Human Stem Cell Factor (SCF) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. SCF is a pleiotropic factor that acts in utero in germ cell and neural cell development and hematopoiesis. These activities are all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. The lyophilized, E. coli-expressed SCF CTS™ Recombinant Human is verified for activity through dose-dependent proliferation of human MO-7e cells.

Qualified—helps reduce your burden in qualifying reagents for regulatory submission in cell therapy applications
Highly Pure—minimizes interference from other proteins or contaminants
Active—get more results with less protein

Simplified Transition into Clinical Research
GIBCO® CTS™ products are of high quality and supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate. The GIBCO® CTS™ product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our SCF CTS™ Recombinant Human growth factor is determined by the dose-dependent proliferation of human MO-7e cells to have an ED50 range of 2 to 10 ng/mL (specific activity: 5 × 105–1 × 105 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
Cell Therapy Systems Technical Support Web Page
Our Full Collection of GIBCO® CTS™ Growth Factors
Our Full Collection of GIBCO® Growth Factors

IL7 Recombinant Mouse Protein (Gibco™)

Recombinant IL7 is a bioactive protein intended for use in cell culture applications. IL7 stimulates the proliferation of pre-B and pro-B cells. IL7 also supports the maturation of megakaryocytes.

FGF4 Recombinant Human Protein (Gibco™)

Recombinant Human Fibroblast Growth Factor 4 (FGF4) is a bioactive protein intended for use in cell culture applications. FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Studies on the mouse homolog suggest a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Fibroblast Growth Factor 4 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Fibroblast Growth Factor 4 (FGF4) specific activity is determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

M-CSF AOF, Recombinant Human Protein (Gibco™)

Recombinant Human Macrophage Colony-Stimulating Factor (M-CSF) is a bioactive protein intended for use in cell culture applications. M-CSF is induces proliferation and differentiation of hematopoietic stem cells into macrophages and growth and differentiation of monocytes.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Macrophage Colony-Stimulating Factor is one of our more than 250 available Gibco® recombinant proteins . To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Macrophage Colony-Stimulating Factor (M-CSF) specific activity is determined by measuring the dose dependent stimulation of proliferation of mouse M-NFS-60 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

RANTES Recombinant Human Protein (Gibco™)

Recombinant RANTES is a bioactive protein intended for use in cell culture applications. RANTES functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. RANTES is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.

TNF Recombinant Human Protein, Liquid Form (Gibco™)

Recombinant Human Tumor Necrosis Factor-α (TNF) is a bioactive protein intended for use in cell culture applications. TNF causes cytolysis and cytostasis of many tumor cell lines. TNF has a wide spectrum of activities, including chemotaxis of neutrophils, alteration of the endothelium, inhibition of anticoagulatory mechanisms, and promotion of angiogenesis.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Tumor Necrosis Factor-α is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Tumor Necrosis Factor-α (TNF) specific activity is determined by the dose dependent cytotoxic effect on L929 cells in the presence of actinomycin D.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL8 Monocyte Recombinant Human Protein (Gibco™)

Recombinant IL8 Monocyte is a bioactive protein intended for use in cell culture applications. IL8 is chemotactic for all known types of migratory immune cells. IL8 also inhibits the adhesion of leukocytes to activated endothelial cells.