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IL4 (Interleukin 4) CTS™ Recombinant Human Protein (Gibco™)

Recombinant IL4 is a bioactive protein intended for use in cell culture applications. IL4 promotes the proliferation and differentiation of activated B cells. In addition, IL4 up-regulates class II MHC antigen expression and IgE receptors. ED50 = 0.05 to 0.4 ng⁄mL (Specific Activity: 2.0 x 10^7 to 2.5 x 10^6 units⁄mg). The biological activity is determined by measuring the dose-dependent proliferation of human TF-1 cells. A concentration range of 0.1 to 10.0 ng⁄mL is effective for most in vitro applications.

IL6 Recombinant Mouse Protein (Gibco™)

Recombinant Mouse Interleukin 6 (IL6) is a bioactive protein intended for use in cell culture applications. IL6 is a pleiotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Mouse Interleukin 6 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Mouse Interleukin 6 (IL6) specific activity is determined by the dose dependent proliferation of mouse B9 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL6 (Interleukin 6) CTS™ Recombinant Human Protein (Gibco™)

Cell Therapy Systems (CTS™) Recombinant Human Interleukin 6 (IL6) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. IL6 is a pleotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response. The lyophilized, E. coli-expressed IL6 CTS™ Recombinant Human is verified for activity through dose-dependent proliferation of mouse B9 cells.

Qualified—helps reduce your burden in qualifying reagents for regulatory submission in cell therapy applications
Highly Pure—minimizes interference from other proteins or contaminants
Active—get more results with less protein

Simplified Transition into Clinical Research
GIBCO® Cell Therapy Systems (CTS™) products are of high quality and supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate. The GIBCO® CTS™ product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our IL6 CTS™ Recombinant Human growth factor is determined by the dose-dependent proliferation of mouse B9 cells to have an ED50 range of 0.008–0.02 ng/mL (specific activity: 1.25 × 10^8–5.0 × 10^7 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
Cell Therapy Systems Technical Support Web Page
Our Full Collection of GIBCO® CTS™ Growth Factors
Our Full Collection of GIBCO® Growth Factors

IFN-β Recombinant Rat Protein (Gibco™)

Recombinant IFN-β is a bioacitve protein intended for use in cell culture applications. IFN-β is involved in immune responses against viral infection.

IL2 Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 2 (IL2) is a bioactive protein intended for use in cell culture applications. IL2 causes proliferation of T-cells and is a central regulator of immune responses.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 2 (IL2) specific activity is determined by the dose dependent proliferation of mouse CTLL-2 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IFN-γ Recombinant Rat Protein (Gibco™)

Recombinant IFN-γ is a bioactive protein intended for use in cell culture applications. Recombinant rat IFN-γ is intended for use in cell culture applications. IFN-γ is involved in many biological processes such as inducing the secretion of TNF-α and stimulating the release of reactive oxygen species from macrophages. It is also involved with bone growth and inhibits bone reesorption. It is antiviral and antiparasitic and inhibits the proliferation of cells.

IL1A Recombinant Human Protein (Gibco™)

Recombinant IL1A is a bioactive protein intended for use in cell culture applications. IL-1 is involved in a number of biological process including the stimulation of T-helper cells, promotion proliferation and synthesis of immunoglobulins, and the activation of fibroblasts and NK cells.

TECK Recombinant Human Protein (Gibco™)

Recombinant TECK is a bioactive protein intended for use in cell culture applications. TECK displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils.

IP10 Recombinant Mouse Protein (Gibco™)

Recombinant IP10 is a bioactive protein intended for use in cell culture applications. IP10 is a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

TGFB3 Recombinant Human Protein (Gibco™)

Recombinant Human Transforming Growth Factor β 3 (TGFB3) is a bioactive protein intended for use in cell culture applications. TGFB3 is involved in epithelial and endothelial cell proliferation and differentiation during development.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Transforming Growth Factor β 3 is one of more than 250 Gibco® recombinant proteins available from Life Technologies. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 3 (TGFB3) specific activity is determined in a toxicity assay using WHO Standard 98/608 for direct comparison.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL7 (Interleukin 7) CTS™ Recombinant Human Protein (Gibco™)

Recombinant IL7 is a bioactive protein intended for use in cell culture applications. IL7 stimulates the proliferation of pre-B and pro-B cells. IL7 also supports the maturation of megakaryocytes. ED50 range = 0.2 to 1 ng⁄mL (Specific Activity: 5.0 x 10^6 to 1.0 x 10^6 units⁄mg), determined by the dose dependent proliferation of human PBMCs. Optimal concentration for individual application should be determined by a dose response assay.

IL20 Recombinant Human Protein (Gibco™)

Recombinant IL20 is a bioactive protein intended for use in cell culture applications. There are two heterodimeric receptor complexes for IL20. The first is composed of IL20 Ra and IL20 Rb. The second is composed of IL-22 R and IL20b. IL20 induces the proliferation of multipotential hematopoietic progenitor cells, directs the differentiation and expansion of keratinocytes, and promotes the release of proinflammatory mediators in keratinocytes and other cells expressing the IL20 receptor.

IL15 Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 15 (IL15) is a bioactive protein intended for use in cell culture applications. IL15 activity resembles some biological activities attributed to IL-2. IL15 induces proliferation of PMA activated peripheral blood mononuclear cells. IL15 also functions as a maturation factor for NK cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 15 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 15 (IL15) specific activity is determined by measuring the dose-dependent proliferation of mouse CTLL-2 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Soluble CD40L (TRAP) Recombinant Human Protein (Gibco™)

Recombinant Human soluble CD40 Ligand (sCD40L, TRAP) is a bioactive protein intended for use in cell culture applications. Soluble CD40L regulates B cell function by engaging CD40 on the B cell surface. This is the 10 microgram size.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human soluble CD40 Ligand is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human soluble CD40 Ligand (sCD40L, TRAP) specific activity is determined by measuring the dose-dependent stimulation of IL-12 production by isolated human PBMC's.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

IL3 Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 3 (IL3) is a bioactive protein intended for use in cell culture applications. IL3 provides the cytokine connection between the immune system and the hematopoietic system. For example, IL3 supports the proliferation and development of almost all types of hematopoietic progenitor cells and can act as a chemoattractant for eosinophils.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 3 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 3 (IL3) specific activity is determined by the dose dependent proliferation of human TF-1 cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.