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IL17 Recombinant Human Protein (Gibco™)

Recombinant IL17 is a bioactive protein intended for use in cell culture applications. IL17 stimulates epithelial, endothelial or fibroblastic cells to secrete IL-6, IL-8 and G-CSF. IL17 also increases the expression of ICAM-1 in fibroblasts.

SDF1A Recombinant Human Protein (Gibco™)

Recombinant SDF1A is a bioactive protein intended for use in cell culture applications. SDF-1αis a small cytokine that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL-1.

IL1B Recombinant Human Protein (Gibco™)

Recombinant Human Interleukin 1, beta (IL1B) is a bioactive protein intended for use in cell culture applications. IL-1 is involved in a number of biological processes including the stimulation of T-helper cells, promotion proliferation and synthesis of immunoglobulins, and the activation of fibroblasts and NK cells.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Interleukin 1, beta is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Interleukin 1, beta (IL1B) specific activity is determined by the dose dependent proliferation of murine D10S cells.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

BDNF Recombinant Human Protein (Gibco™)

Recombinant Human Brain-Derived Neurotrophic Factor (BDNF) is a bioactive protein intended for use in cell culture applications. BDNF is a neurotrophic factor involved in the survival and differentiation of neurons in the central and peripheral nervous system.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Brain-Derived Neurotrophic Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Brain-Derived Neurotrophic Factor (BDNF) specific activity is determined by measuring the dose dependent induction of choline acetyltransferase activity in rat basal forebrain primary septal cultures.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

FGF-Basic (AA 10-155) Recombinant Human Protein (Gibco™)

FGF-Basic (AA 10-155) is a bioactive protein intended for use in cell culture applications. Fibroblast growth factor-basic is known as FGF-basic, bFGF, FGF 2, FGF-β, and heparin binding growth factor. FGF-basic is involved in a number of biological processes, including embryonic development and differentiation, neuron differentiation, survival, regeneration, and the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin.

Features of recombinant human FGF-basic:

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—proteins bioassayed with Gibco® media

High-purity, recombinant, bioactive protein
Human FGF-basic (AA 10-155) is one of our more than 250 available recombinant proteins. To help ensure our growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant human FGF-basic specific activity is determined by the dose dependent proliferation of BALB/3T3 cells.

Proven compatibility
Our recombinant proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

TGFB1 CTS™ Recombinant Human Protein (Gibco™)

Cell Therapy Systems CTS™ Recombinant Human TGF beta 1 (TGFB1) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. TGFB1 acts synergistically with TGF-α in inducing transformation and acts as a negative autocrine growth factor. Dysregulation of TGFB1 activation and signaling may result in apoptosis. The lyophilized TGFB1 CTS™ Recombinant Human is verified for activity through dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4.

Qualified—helps reduce your burden in qualifying reagents for regulatory submission in cell therapy applications
Highly Pure—minimizes interference from other proteins or contaminants
Active—get more results with less protein

Simplified Transition into Clinical Research
GIBCO® Cell Therapy Systems (CTS™) products are of high quality and supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate. The GIBCO® CTS™ product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our TGFB1 CTS™ Recombinant Human growth factor is determined by the dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4 to have an ED50 ≤0.2ng/mL. Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
Cell Therapy Systems Technical Support Web Page
Our Full Collection of GIBCO® CTS™ Growth Factors
Our Full Collection of GIBCO® Growth Factors

FGF19 Recombinant Human Protein (Gibco™)

Recombinant human FGF19 is a bioactive protein intended for use in cell culture applications. FGF19 is a member of the FGF family of proteins.

MIP-5 Recombinant Human Protein (Gibco™)

Recombinant MIP-5 is a bioactive protein intended for use in cell culture applications. MIP-5 (Macrophage inflammatory protein-5 also known as CCL15 and MIP-1δ) is a chemoattractant for monocytes, T-lymphocytes and eosinophils.

MIP-3-alpha Recombinant Human Protein (Gibco™)

Recombinant MIP-3-alpha is a bioactive protein intended for use in cell culture applications. MIP-3-alpha (Macrophage inflammatory protein-3α) is a chemokine and is also known as CCL20.

TGFB2 Recombinant Human Protein (Gibco™)

Recombinant Human Transforming Growth Factor β 2 (TGFB2) is a bioactive protein intended for use in cell culture applications. TGFB2 binds the transforming growth factor-β receptor and plays a role in regulation of cell growth and proliferation. It may be involved in mesenchymal-epithelial cell interactions during development.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Transforming Growth Factor β 2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 2 (TGFB2) specific activity is determined by its ability to inhibit the mouse IL-4 dependent proliferation of mouse HT-2 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Activin A Recombinant Human Protein (Gibco™)

Recombinant Human Activin A is a bioactive protein intended for use in cell culture applications. Activin A is involved in multiple biological processes including inflammation, neural development, and haematopoiesis.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Activin A is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Activin A specific activity is determined by the dose dependent proliferation of mouse MPC-11 cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

SCF Recombinant Human Protein, Animal-Origin Free (Gibco™)

Recombinant Human Stem Cell Factor (SCF, c-kit Ligand) is a bioactive protein intended for use in cell culture applications. SCF is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High purity recombinant bioactive protein
Recombinant Human Stem Cell Factor is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High biological activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Stem Cell Factor (SCF, c-kit Ligand) specific activity is determined by the dose dependent proliferation of human MO-7e cells.

Proven compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Eotaxin Recombinant Human Protein (Gibco™)

Recombinant human eotaxin is a bioactive protein intended for use in cell culture applications. Eotaxin is a member of the PF-4 family of chemokines. Eotaxin plays a role in inducing calcium flux in eosinophils.

SDF1B Recombinant Human Protein (Gibco™)

Recombinant SDF1B is a bioactive protein intended for use in cell culture applications. SDF1B is a small cytokine that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL-1.

BMPR1A Recombinant Human Protein (Gibco™)

Bone Morphogenetic Protein Receptor 1A (BMPR1A) Fc Chimera is a bioactive protein intended for use in cell culture applications. BMPR1A is one of the bone morphogenetic protein (BMP) receptors which are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Bone Morphogenetic Protein Receptor 1A Fc Chimera is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Bone Morphogenetic Protein Receptor 1A (BMPR1A) specific activity is determined by its ability to inhibit human BMP4induction of alkaline phosphatase in the mouse chondrogenic cell line ATDC5.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.