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Products

NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer Thermo Scientific™

Prevent costly delays with an enhanced understanding of sample quality using the Thermo Scientific™ NanoDrop™ One Microvolume UV-Vis Spectrophotometers. Innovative Thermo Scientific™ Acclaro™ Sample Intelligence technology is built into every instrument for improved measurement accuracy and contaminant identification. Quantify and qualify DNA, RNA, and protein samples  in seconds with only 1-2 µL, and obtain full-spectral data before you decide to use samples in downstream applications. Additional cuvette position also available.

NanoDrop™ 8000 Spectrophotometer Thermo Scientific™

Accelerate your research with the Thermo Scientific™ NanoDrop™ 8000 Microvolume UV-Vis Spectrophotometer providing quick, easy nucleic acid and protein quantification.Perfect for higher throughput workflows, the NanoDrop 8000 instrument can measure multiple samples simultaneously using only 1- 2 μL of sample. Using an 8-channel pipette to dispense samples on a linear array of pedestals, you can easily measure 96 samples in less than six minutes.

NanoDrop™ 2000/2000c Spectrophotometers Thermo Scientific™

Thermo Scientific™ NanoDrop 2000 and 2000c are full-spectrum, UV-Vis spectrophotometers used to quantify and assess purity of DNA, RNA, Protein and more. The NanoDrop 2000 and 2000c are the only microvolume spectrophotometers with patented sample retention technology that measure sample volumes as small as 0.5μL.

NanoDrop™ Lite Spectrophotometer Thermo Scientific™

The Thermo Scientific™ NanoDrop Lite Spectrophotometer is a compact, personal UV-Vis microvolume spectrophotometer that complements the full-featured NanoDrop 2000/2000c and NanoDrop 8000 instruments. While the NanoDrop Lite is designed with fewer features than the NanoDrop 2000 or NanoDrop 8000 series, it delivers where it counts: rapid, accurate and reproducible microvolume measurements without the need for dilutions. It uses the same sample retention system that has become a hallmark of NanoDrop instruments; the sample is held in place by surface tension only.

NanoDrop™ 3300 Fluorospectrometer Thermo Scientific™

Choose the versatile, cost-effective Thermo Scientific™ NanoDrop 3300 Fluorospectrometer for broad spectrum fluorescence analysis. Using a patented technology, it uses as little as 1 μL of sample volume.

NanoDrop™ One Spectrophotometer with WiFi & Qubit™ 4 Fluorometer Invitrogen™

For DNA, RNA or protein samples that are 100% pure, the results obtained on the Thermo Scientific™ NanoDrop™ One Microvolume UV-Vis Spectrophotometer and the Invitrogen Qubit 4 Fluorometer would be identical for samples within their dynamic ranges. However, few samples are 100% pure.

As a bundled offering, the NanoDrop One Microvolume UV-Vis Spectrophotometer and the Qubit 4 Fluorometer together allow you to obtain the most complete information about the concentration and quality of your DNA, RNA or protein samples—helping to prevent costly troubleshooting downstream. While both the NanoDrop One spectrophotometer and the Qubit 4 fluorometer offer accurate measurements of DNA, RNA and protein samples, each also has its unique advantages.

NanoDrop One Spectrophotometer
Cited in more than 30,000 publications, the NanoDrop UV-Vis microvolume spectrophotometers have fundamentally changed the way scientists evaluate nucleic acid and protein samples by minimizing the need for large sample volumes.

The next generation NanoDrop One Microvolume UV-Vis Spectrophotometer utilizes innovative Thermo Scientific Acclaro™ Sample Intelligence technology that identifies contaminants, provides corrected concentration values and helps you understand the quality of your sample before you use it in downstream applications.

Qubit 4 Fluorometer
The Qubit 4 Fluorometer is a cutting-edge benchtop device that accurately measures DNA, RNA, and protein quantity, and now also RNA integrity and quality, using the highly sensitive Qubit assays.

For all Qubit assays, the concentration or quality of the target molecule in the sample is reported by a fluorescent dye that emits a signal only when bound to the target, which minimizes the effects of contaminants on the result. The easy-to-use touchscreen menus make it easy to select and run the assays you need, with results displayed in just a few seconds.

Comparison of the NanoDrop One spectrophotometer and Qubit 4 Fluorometer

NanoDrop One Spectrophotometer

 

Qubit 4 Fluorometer

Fast and simple. Allows for direct measurement of purified samples with no dilutions required.

Overview

Sensitive and specific. Accurately measures concentration whether dsDNA, ssDNA, total RNA, microRNA or protein— even in the presence of contaminants.

UV absorbance

Technology

Fluorescence

Pipette sample onto pedestal; measure.

Workflow

Mix sample with reagents, incubate for 2–5 minutes, read.

Routine quantitation and qualification of DNA, RNA and proteins

Applications

Routine samples and with very dilute or difficult to process samples, when higher measurement sensitivity is required or when nucleic acid contaminants are suspected (e.g., DNA in RNA, dNTPs)

RNA sample quality

0.21–27,500

dsDNA quantitation range (ng/ul)

0.01–1,000

Acclaro Sample Intelligence technology identifies presence of contaminants such as protein or guanidine; provides corrected analyte concentration value.

Sample qualification (purity)

Unique fluorescent dyes enable differentiation between nucleic acid types (e.g., DNA vs. RNA) without any sample pre-treatment.

RNA IQ assay enables fast and facile detection of intact vs degraded in <5 seconds per sample

Selection of pre-programmed applications

  • Direct A280 quantitation with Protein Editor
  • A205 peptide bond absorbance
  • Colorimetric protein assays: Bradford, BCA, Lowry and Thermo Scientific Pierce™ 660 nm assay

Protein Quantitation

Qubit assays exhibit minimal protein-to-protein variability and are resistant to most contaminants, including salts, reducing agents (e.g., DTT, b-mercaoptoethanol), DNA or amino acids, but not detergents.

1dsDNA quantitation range for NanoDrop One is 0.2 ng/µL with cuvette and 2.0 ng/µL without.

Key instrument features include:

NanoDrop One Microvolume UV-Vis Spectrophotometer
• Fast and easy sample evaluation of nucleic acids and proteins with “pipette, measure, clean” workflow and no sample carryover
• Modern stand-alone design with local control and high-resolution touchscreen interface, which saves bench space
• Accurate measurements up to 27,500 ng/µL (dsDNA) with extended auto-range path length technology
• No need for cuvettes or consumables needed so you can pipette directly onto pedestal sample retention system
• Pre-programmed applications designed specifically for life scientists
• Enhanced connectivity with data transfer via USB, Ethernet, Bluetooth™ and WiFi options; PC software available for data management

Qubit 4 Fluorometer
• Fast and highly accurate quantitation of DNA, RNA, and protein in less than three seconds per sample
• Measures intact RNA in less than 5 seconds per sample
• High levels of accuracy using only 1–20 μL of sample, even with very dilute samples
• On-board Reagent Calculator quickly generates Qubit working solution preparation instructions
• Stores results from up to 1000 samples
• Large 5.7-inch, state-of-the-art color touchscreen for easy workflow navigation
• Graphical display indicates when samples are in the extended range or out of range
• Small footprint saves space on your bench
• Exports data to a USB drive or directly to your computer via a USB cable
• Ability to personalize your Qubit fluorometer with the assays you run most, add new assays, or even create your own assays with the MyQubit software and web tool
• Language of your choice including English, French, Spanish, Italian, German, simplified Chinese, and Japanese

NanoDrop™ Lite Printer Accessory Thermo Scientific™

Use the Thermo Scientific™ NanoDrop™ Lite Printer, an optional printer docking station, with your NanoDrop Lite spectrophotometer.

NanoDrop™ One/OneC Productivity Kits Thermo Scientific™

The Thermo Scientific™ NanoDrop™ One and NanoDrop™ OneC Productivity Kits allow you to improve the productivity of your NanoDrop One and NanoDrop OneC Microvolume UV-Vis Spectrophotometers.

NanoDrop™ PR-1 Reconditioning Kit Thermo Scientific™

Thermo Scientific™ NanoDrop PR-1 Reconditioning Kit is used for reconditioning the sample measurement pedestals to a hydrophobic state if they become unconditioned.

NanoDrop™ CF-8 Calibration Check Kit Thermo Scientific™

Thermo Scientific™ NanoDrop CF-8 Calibration Check Kit is an aqueous potassium dichromate (K2Cr2O7) solution for use in confirming spectrophotometer calibration.

NanoDrop QC Software for the NanoDrop OneC Spectrophotometer Thermo Scientific™

Thermo Scientific™ NanoDrop™ QC Software for the NanoDrop OneC Spectrophotometer is equipped with auto-ranging pathlengths that accurately measure up to 550 AU of UV-Vis absorbance of liquid polymers/chemicals without dilution. Pedestal pathlengths are controlled automatically, so no prior knowledge of sample concentration is necessary. The software runs chemometric algorithms built in Thermo Scientific™ TQ Analyst™ software and provides results within seconds. It is ideal for production quality control or R&D labs and works with a variety of solutions including adhesives and lubricants.

NanoDrop™ Dymo LabelWriter 450 Printer with labels Thermo Scientific™

The Thermo Scientific™ NanoDrop™ Dymo LabelWriter 450 Printer is a convenient accessory for NanoDrop instruments. It prints sample data onto self-adhesive labels, which are included with purchase of printer.

NanoDrop™ OneC Spectrophotometer with WiFi & Qubit™ 4 Fluorometer Invitrogen™

For DNA, RNA or protein samples that are 100% pure, the results obtained on the Thermo Scientific™ NanoDrop™ OneC Microvolume UV-Vis Spectrophotometer and the Invitrogen™ Qubit™ 4 Fluorometer would be identical for samples within their dynamic ranges. However, few samples are 100% pure.

As a bundled offering, the NanoDrop OneC Microvolume UV-Vis Spectrophotometer and the Qubit 4 Fluorometer together allow you to obtain the most complete information about the concentration and quality of your DNA, RNA or protein samples—helping to prevent costly troubleshooting downstream. While both the NanoDrop OneC spectrophotometer and the Qubit 4 fluorometer offer accurate measurements of DNA, RNA and protein samples, each also has its unique advantages.

NanoDrop OneC Spectrophotometer
Cited in more than 30,000 publications, the NanoDrop UV-Vis microvolume spectrophotometers have fundamentally changed the way scientists evaluate nucleic acid and protein samples by minimizing the need for large sample volumes.

The next generation NanoDrop OneC Microvolume UV-Vis Spectrophotometer utilizes innovative Thermo Scientific Acclaro™ Sample Intelligence technology that identifies contaminants, provides corrected concentration values and helps you understand the quality of your sample before you use it in downstream applications.

Qubit 4 Fluorometer
The Qubit 4 Fluorometer is a cutting-edge benchtop device that accurately measures DNA, RNA, and protein quantity, and now also RNA integrity and quality, using the highly sensitive Qubit assays.

For all Qubit assays, the concentration or quality of the target molecule in the sample is reported by a fluorescent dye that emits a signal only when bound to the target, which minimizes the effects of contaminants on the result. The easy-to-use touchscreen menus make it easy to select and run the assays you need, with results displayed in just a few seconds.

Comparison of the NanoDrop OneC spectrophotometer and Qubit 4 fluorometer

NanoDrop OneC Spectrophotometer

 

Qubit 4 Fluorometer

Fast and simple. Allows for direct measurement of purified samples with no dilutions required.

Overview

Sensitive and specific. Accurately measures concentration whether dsDNA, ssDNA, total RNA, microRNA or protein— even in the presence of contaminants.

UV absorbance

Technology

Fluorescence

Pipette sample onto pedestal; measure.

Workflow

Mix sample with reagents, incubate for 2–5 minutes, read.

Routine quantitation and qualification of DNA, RNA and proteins

Applications

Routine samples and with very dilute or difficult to process samples, when higher measurement sensitivity is required or when nucleic acid contaminants are suspected (e.g., DNA in RNA, dNTPs)

RNA sample quality

0.21–27,500

dsDNA quantitation range (ng/ul)

0.01–1,000

Acclaro Sample Intelligence technology identifies presence of contaminants such as protein or guanidine; provides corrected analyte concentration value.

Sample qualification (purity)

Unique fluorescent dyes enable differentiation between nucleic acid types (e.g., DNA vs. RNA) without any sample pre-treatment.

RNA IQ assay enables fast and facile detection of intact vs degraded in <5 seconds per sample

Selection of pre-programmed applications

  • Direct A280 quantitation with Protein Editor
  • A205 peptide bond absorbance
  • Colorimetric protein assays: Bradford, BCA, Lowry and Thermo Scientific Pierce™ 660 nm assay

Protein quantitation

Qubit assays exhibit minimal protein-to-protein variability and are resistant to most contaminants, including salts, reducing agents (e.g., DTT, b-mercaoptoethanol), DNA or amino acids, but not detergents.

1dsDNA quantitation range for NanoDrop OneC is 0.2 ng/µL with cuvette and 2.0 ng/µL without.

Key instrument features include:

NanoDrop OneC Microvolume UV-Vis Spectrophotometer
• Fast and easy sample evaluation of nucleic acids and proteins with “pipette, measure, clean” workflow and no sample carryover
• Modern stand-alone design with local control and high-resolution touchscreen interface, which saves bench space
• Accurate measurements up to 27,500 ng/µL (dsDNA) with extended auto-range path length technology
• No need for cuvettes or consumables needed so you can pipette directly onto pedestal sample retention system
• Pre-programmed applications designed specifically for life scientists
• Enhanced connectivity with data transfer via USB, Ethernet, Bluetooth™ and WiFi options; PC software available for data management
• Cuvette position for measuring dilute solutions and performing temperature sensitive experiments with the NanoDrop OneC spectrophotometer

Qubit 4 Fluorometer
• Fast and highly accurate quantitation of DNA, RNA, and protein in less than three seconds per sample
• Measures intact RNA in less than 5 seconds per sample
• High levels of accuracy using only 1–20 μL of sample, even with very dilute samples
• On-board Reagent Calculator quickly generates Qubit working solution preparation instructions
• Stores results from up to 1000 samples
• Large 5.7-inch, state-of-the-art color touchscreen for easy workflow navigation
• Graphical display indicates when samples are in the extended range or out of range
• Small footprint saves space on your bench
• Exports data to a USB drive or directly to your computer via a USB cable
• Ability to personalize your Qubit fluorometer with the assays you run most, add new assays, or even create your own assays with the MyQubit software and web tool
• Language of your choice including English, French, Spanish, Italian, German, simplified Chinese, and Japanese

NanoDrop™ CF-1 Calibration Fluid, 0.5mL ampule Thermo Scientific™

Thermo Scientific™ NanoDrop CF-1 Calibration Fluid is an aqueous potassium dichromate (K2Cr207) solution for use in confirming spectrophotometer calibration.

Validation Tools for UV-Visible Spectrophotometers Thermo Scientific™

Get all of the documentation and reference materials needed to facilitate Installation and Operational qualification procedures (IQ/OQ) with Thermo Scientific™ Validation Tools for UV-Visible Spectrophotometers. Certified standards for verifying instrument performance to factory specifications are available separately.
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