Ion AmpliSeq NGS Panels for Targeted Sequencing
One tube. Many answers.
Use DNA or RNA for SNP, CNV, fusion, and indel detection
When analyzing suspected variants in genetic diseases, you need a discovery tool that is both rapid and cost-effective for analyzing multiple genes. Ready-to-use, made-to-order, and on-demand Ion AmpliSeq NGS panels can help.
Ion AmpliSeq panels consist of a pool of oligonucleotide primer pairs, each pair designed to amplify a specified genomic region. Each panel can be designed to interrogate all bases across a gene, or it can be focused on specific mutation hotspots.
Gene panels on demand, how and when you want them
Ion AmpliSeq On-Demand panels bring smaller pack sizes and an optimized catalog of pre-tested genes to custom NGS panels, so you can iterate panel design for human disease research with efficiency and convenience.
Not working with human research samples? No problem.
Design a custom panel from 12 predefined genomes, or from your own reference genome after uploading a reference file.
One tube for CNV, SNP, indel, and fusion detection
Simple, versatile technology based on highly multiplexed PCR helps you target tens to hundreds of genes across mutation types including SNPs, indels, fusions, and copy number variants.
What can you do with NGS using Ion AmpliSeq panels? Get results.
After more than 25,000 custom designs and 600 publications, custom Ion AmpliSeq panels have a track record of superior coverage uniformity, reproducibility, and specificity. They help you get results.
Ion AmpliSeq panels
On-Demand panels
Ion AmpliSeq On-Demand panels enable custom panel design in smaller pack sizes from pre-tested genes for practical customization that helps reduce upfront cost and risk.
RNA-seq panels
Choose from over 20,000 genes to survey gene expression fold changes starting with as little as 500 pg of unfixed RNA or 5 ng of FFPE RNA.
Made-to-order
For maximum flexibility, simply select a subset of targets and enter your specific genomic content online using the Ion AmpliSeq Designer tool, and we will design and create customized Ion AmpliSeq panels just for you. Choose from a number of reference genomes or upload your own reference sequence.
Transcriptome panels
The Ion AmpliSeq Transcriptome Human Gene Expression Kit is ideal for traditional gene expression analysis of known transcripts from the RefSeq database.
Ready-to-use panels
The convenient predesigned Ion AmpliSeq ready-to-use panels allow researchers to focus on data generation and analysis, not on the labor-intensive primer design and target selection steps.
Exome panels
The Ion AmpliSeq Exome RDY S5 Kit allows for rapid, accurate sequencing of key exonic regions of the genome, going from DNA to variants in just 2 days.
Ion AmpliSeq panels by application
Inherited disease research
Deafness, epilepsy, cardiac research, and more
Cancer research
Cancer genomics, cancer RNA expression, and more
Infectious disease research
Tracing the origin of outbreaks, food safety, and more
Human identification
DNA phenotyping, ancestry, and more
Power and speed for targeted NGS analysis
Ion AmpliSeq panels help you get NGS results from more of your challenging FFPE samples. To do it faster, use the Ion S5 System.
Ion AmpliSeq panel results from Boston Children’s Hospital, USA
Applications of targeted NGS panels for clinical research of primary immunodeficiency diseases
Dr. Janet Chou and Wayne Bainter discuss the application of the Ion AmpliSeq Primary Immune Deficiency (PID) Research Panel v2 to accelerate and improve the search for causal variants in clinical research of PIDs.
Vidoes to help you get started
How does Ion AmpliSeq technology work?
Transitioning from Sanger sequencing? It’s easy to get started.
For Research Use Only. Not for use in diagnostic procedures.