Despite significant advancements in the development of preventive treatments for Ebola Virus, the lack of knowledge about its structure has been impeding the progress in treatment and therapeutics. Researchers at the University Hospital Heidelberg in Germany have successfully visualized the process of Ebola virus membrane fusion and cell entry using a combination of cryo-electron tomography (cryo-ET) imaging, digital 3D reconstruction, molecular analysis, and membrane modeling.
Discover how they were able to determine the structure and cell entry mechanism of the Ebola virus by utilizing Thermo Fisher Scientific Titan Krios and Thermo Scientific Amira Software for the 3D segmentation and reconstruction of tomograms.