Discover guidance for reviewing TrueMark MSI Assay fragment analysis data using InnoviGene Suite and GeneMapper Software. This application note demonstrates how to configure analysis settings, visualize electropherograms, and compare matched normal and tumor samples to support MSI data review.
In this application note, you will learn how to:
- Configure InnoviGene Suite and GeneMapper Software for reviewing TrueMark MSI Assay fragment analysis data.
- Apply recommended analysis and plot settings to support standardized MSI fragment profile review.
- Visualize MSI fragment profiles and electropherograms across individual dye channels.
- Compare matched normal and tumor samples, including using overlay views to assess differences in microsatellite peak profiles.
- Review microsatellite and STR sample-identification markers to help assess sample identity and data integrity.
- Evaluate peak shifts, peak morphology, signal intensity, fragment sizing, and sizing quality during manual data review.
- Export electropherogram plots, tables, and reports for documentation and downstream review.