AMP0-2018-hero

As we move closer to realizing the practice of precision medicine, we are committed to developing genetic analysis tools that enable simple and rapid molecular analysis of samples across cancer, infectious disease, and pharmacogenomics. Below are some of the new innovations and solutions showcased at the Association for Molecular Pathology (AMP) 2018 Annual Meeting.  We look forward to seeing you at AMP 2019 in Atlanta, GA.

Workshop image
Booth
Posters


Workshops

In the journey to realizing the promise of precision medicine, NGS has quickly emerged as a helpful tool to study multiple genes and mutation types in a single assay, thus preserving precious samples and significantly reducing the time to results. In this workshop some of the latest NGS innovations in NSCLC research and diagnostics testing are discussed. Additionally, case studies are presented showing how NGS has been successfully implemented in different types of laboratories to streamline the testing.

Learn more ›

Use of immune checkpoint inhibitors (ICIs) in immunotherapies is increasingly common, especially in monotherapy and combination therapy. Tumor Mutational Burden (TMB) has been recently validated as a clinical biomarker in response to ICIs.  Widespread adoption of TMB in a routine setting will require a streamlined turnkey solution in addition to standardized TMB calculation and reporting.  Additionally, new potential biomarkers like TCR clonality can further augment immune therapy success.  This workshop highlights Friends of Cancer Research’s TMB Harmonization Project, how Oncomine Tumor Mutation Load Assay can streamline TMB assessment, and introduces an emerging liquid biopsy biomarker for the development of future immunotherapies using TCR sequencing.

Learn more ›

As the implementation of targeted therapies continues to rise, the relevance of molecular testing in prognosis and treatment management is becoming increasingly apparent. However, clinical gaps, such as which patients should receive therapy and which patients should simply be observed, highlight the need for studies that lend to the identification and standardization of biomarkers that will change the current standards of care in patient management. This workshop examines the studies at various institutions and how they may ultimately lead to diagnostic improvements and better therapeutic management for patients fighting cancer.

Learn more ›

The development of commercially available, panel-based molecular pathogen detection tests has provided many benefits to laboratories. Some challenges still exist including scalability in throughput, decreasing cost per sample, and increasing content flexibility to meet the ever-changing needs for detecting pathogenic targets. Our workshop explores how laboratories can drive down the cost of microbial testing with the use of nanofluidic and microfluidic solutions. Hear from laboratories that have implemented this technology, selected their own pathogen targets, all while minimizing the cost of testing using real-time PCR technology.  This workshop focuses on respiratory, vaginal, and urinary tract microbiota detection for research.

Learn more ›

As healthcare costs continue to rise, health delivery systems and providers are under increasing pressure to deliver quality care with decreasing resources. This workshop describes a medication management framework that uses pharmacogenetic (PGx) testing as a component of a holistic medication management strategy, and as such, provides one of the clearest opportunities for health systems to remain competitive and reduce costs while improving patient outcome. Hear how programs around the world use PGx testing to improve financial and health outcomes and the impact on healthcare program ROI metrics.

Learn more ›

Featured products and solutions


Posters

Genetics

What can we learn from oncologists?  A survey of molecular testing patterns
J. Menezes
 Download poster ›

High-throughput approach for multi-omic testing for prostate cancer research
M. Shannon, N. Elder
 Download poster ›

Infectious disease

A high throughput system for profiling respiratory tract microbiota
J. Li
 Download poster ›

Informatics

A clinical decision support software to integrate next-generation sequencing and cytogenetics assays for myeloid cancers
S. Bandla
 Download poster ›

Technical topics

Novel spatial multiplex screening of uropathogens associated with urinary tract microbiota research using the nanofluidic qPCR platform
S. Patel
 Download poster ›

Liquid biopsy quality control – the importance of plasma quality, sample preparation, and library input for next generation sequencing analysis
J. Whiting
 Download poster ›

Developing a customizable panel of real-time qPCR assays on a microfluidic device for respiratory tract pathogen detection
K. Li
 Download poster ›

Solid tumors

T-cell receptor beta immune repertoire sequencing in several FFPE tissue types—interrogation of the tumor microenvironment in archived tissue samples
G. Lowman
 Download poster ›

Association of microsatellite instability and tumor mutation burden
J. Au-Young
 Download poster ›

Novel Solvent-Free Deparaffinization Method for FPPE Sample Prep Enabling a More Convenient Workflow
A. Cheng
 Download poster ›

Development of quality control materials for characterization of comprehensive next-generation sequencing panels targeting cancer hotspots
M. Christian
 Download poster ›

Streamlined next generation sequencing assay development using a highly multiplexed FFPE quality control technology based on the Genome in a Bottle
L. C. Liu
 Download poster ›

Analytical validation of the Oncomine Comprehensive Assay v3 with clinical FFPE and cell line tumor specimens in a CAP-accredited and CLIA-certified clinical laboratory
A. Yuki, J. Chitwood
 Download poster ›

Evaluation of ctDNA extraction methods and amplifiable copy number yield using standardized human plasma-based ctDNA control materials
L. C. Liu
 Download poster ›