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IMSC 2022
Tradeshow
Aug 27, 2022
- Sep 02, 2022
Maastricht Exhibition & Congress Centre (MECC) | Maastricht, Netherlands
Your vision. Our innovation.
It was great seeing everyone again at this year’s IMSC conference. If you would like a copy of any of our scientific posters or would like to listen to one of our lunch symposia on demand, please register below.
Lunch symposia
New Tools for Confident Proteoforms and Macromolecules Analysis
Rosa Viner, Senior Manager, Structural Biology, Omics Vertical Marketing, Thermo Fisher Scientific, Tarick El-Baba, Senior Researcher Department of Chemistry, University of Oxford, United Kingdom and Marie Sklodowska, Curie Fellow at University of Oxford, United Kingdom
Detecting individual ion signals, rather than traditional packets of ions, advances Orbitrap-based resolution and charge detection capabilities. To this end, individual ion mass spectrometry alters spectral outputs directly into the Dalton domain to deconvolute complex protein mixtures and determine mass distributions for large particles ranging from 8 kDa to 6 MDa. This workshop will highlight new technologies coupled with easy-to-handle analysis software that advances charge detection capabilities and mass range of macromolecules that can be analyzed.
A New Experience in Automated Proteomics Sample Preparation for Quantitative Proteomics
Daniel Lopez Ferrer, Director of Proteomics and Translational Research, Thermo Fisher Scientific and Kay Oppermann, PhD, Senior Product Manager, MS & Cryo-EM Reagents, Thermo Fisher Scientific
Break free from the time, cost, and complexity of manual sample preparation. This workshop will discuss the challenges of automated proteomics sample preparation and what is needed to overcome these so that scientists can achieve high quality experimental results and focus their time on more valuable tasks. Attributes such as ease-of-use, experimental design, flexible workflows, and integration into existing proteomics infrastructure will be discussed with the scientific community.
Intelligent Data Acquisition Strategies for TMT Multiplexed Single Cell Proteomics Applied on Human Hematopoiesis
Benjamin Furtwängler, Porse Group at Copenhagen University and Schoof Lab at the Technical University of Denmark (DTU)
TMT multiplexed proteomics is mandatory to go beyond analyzing one single cell at a time with high throughput and quantitative accuracy that enables several hundreds of cells to be analyzed per day in order to achieve biological insights. Real time search acquisition methods unique to Orbitrap Tribrid mass spectrometers have delivered two strategies that will provide new capabilities for TMT multiplexed single cell proteomics. Real time search-MS3 provides a much higher quantitative accuracy with similar proteome coverage to standard MS2 methods, this higher accuracy could be used to model protein networks. Here we will discuss the new RETICLE (real time search enhanced quant of single cell spectra) approach that makes use of fast real time searched ion trap scans to significantly improve proteome coverage over MS2 methods and hence high throughput applications such as building single-cell atlases.
Lunch symposia
New Tools for Confident Proteoforms and Macromolecules Analysis
Rosa Viner, Senior Manager, Structural Biology, Omics Vertical Marketing, Thermo Fisher Scientific, Tarick El-Baba, Senior Researcher Department of Chemistry, University of Oxford, United Kingdom and Marie Sklodowska, Curie Fellow at University of Oxford, United Kingdom
Detecting individual ion signals, rather than traditional packets of ions, advances Orbitrap-based resolution and charge detection capabilities. To this end, individual ion mass spectrometry alters spectral outputs directly into the Dalton domain to deconvolute complex protein mixtures and determine mass distributions for large particles ranging from 8 kDa to 6 MDa. This workshop will highlight new technologies coupled with easy-to-handle analysis software that advances charge detection capabilities and mass range of macromolecules that can be analyzed.
A New Experience in Automated Proteomics Sample Preparation for Quantitative Proteomics
Daniel Lopez Ferrer, Director of Proteomics and Translational Research, Thermo Fisher Scientific and Kay Oppermann, PhD, Senior Product Manager, MS & Cryo-EM Reagents, Thermo Fisher Scientific
Break free from the time, cost, and complexity of manual sample preparation. This workshop will discuss the challenges of automated proteomics sample preparation and what is needed to overcome these so that scientists can achieve high quality experimental results and focus their time on more valuable tasks. Attributes such as ease-of-use, experimental design, flexible workflows, and integration into existing proteomics infrastructure will be discussed with the scientific community.
Intelligent Data Acquisition Strategies for TMT Multiplexed Single Cell Proteomics Applied on Human Hematopoiesis
Benjamin Furtwängler, Porse Group at Copenhagen University and Schoof Lab at the Technical University of Denmark (DTU)
TMT multiplexed proteomics is mandatory to go beyond analyzing one single cell at a time with high throughput and quantitative accuracy that enables several hundreds of cells to be analyzed per day in order to achieve biological insights. Real time search acquisition methods unique to Orbitrap Tribrid mass spectrometers have delivered two strategies that will provide new capabilities for TMT multiplexed single cell proteomics. Real time search-MS3 provides a much higher quantitative accuracy with similar proteome coverage to standard MS2 methods, this higher accuracy could be used to model protein networks. Here we will discuss the new RETICLE (real time search enhanced quant of single cell spectra) approach that makes use of fast real time searched ion trap scans to significantly improve proteome coverage over MS2 methods and hence high throughput applications such as building single-cell atlases.
New products presented at IMSC
Thermo Scientific Orbitrap Ascend Tribrid MS
Quantify more samples at lower concentrations, achieve greater coverage with faster acquisition, and characterize the largest biopharmaceuticals with the Orbitrap Ascend Tribrid MS.
Thermo Scientific AccelerOme automated sample preparation platform
The AccelerOme automated sample preparation platform, with factory-supplied reagents and kits, intuitive software and a unique experimental design experience transforms proteomics sample preparation.
Thermo Scientific Proteome Discoverer 3.0 software
Expands the current platform by adding the CHIMERYS Search Engine, which vastly improves the number of peptide identifications versus the current Sequest HT + INFERYS Rescoring workflow.
Thermo Scientific TMTpro 18-plex label reagents
The newest additions to the next generation of tandem mass tags (TMT) designed to increase the level of sample multiplexing without compromising on protein identification and quantitation.
Thermo Scientific Direct Mass Technology option
Eenables mass measurements with unprecedented clarity by simultaneously determining the mass to charge and charge of analytes and transforms the understanding of complex biotherapeutics and other large macromolecular complexes.
Thermo Scientific BioPharma Finder 5.1 software
Simplify comprehensive biotherapeutic attribute characterization with advanced capabilities to increase throughput and confidence for BioPharma workflows through built for purpose data processing, curation, and reporting in a connected environment to streamline and enable collaboration on a global scale.
SMALDI5 AF ion source by TransMIT
TransMIT Center for Mass Spectrometric Development (TransMIT GmbH, Giessen, Germany) offers integrated high-end solutions for atmospheric-pressure Scanning microprobe Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometric imaging on Orbitrap Exploris platform.
Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS/MS system
New extended linear dynamic range combined with proven high sensitivity ensures you keep ahead of the toughest regulatory methods and business demands.
Thermo Scientific ISQ 7610 Single Quadrupole GC-MS system
NeverVent technology, extended-life detector, and intelligent software eliminate unnecessary downtime to maximize sample throughput.