Feb 21, 2016
- Feb 25, 2016
Join us at MSACL 2016!
February 21, 2016–February 25, 2016
Renaissance Hotel & Convention Center, Palm Springs, California
Visit us at Booth #34-35 to discover our portfolio of chromatography, mass spectrometry, and automated sample preparation solutions. Plus, register for our free, educational workshops featuring industry-leading researchers.
Alternate Sample Preparation Approaches for Your Mass Spectrometry Clinical Research Assays
William Clarke, PhD, MBA, DABCC
The Johns Hopkins University School of Medicine
Tues., Feb. 23 2:00–3:00 p.m. Mojave Room
The first part of this session will focus on the research of cell disintegrated blood (CDB) as a matrix for the analysis of immunosuppressant drugs. Opportunities, challenges, and limitations of CDB will be explored.
The second part of this session will focus on alternate sample preparation approaches for the analysis of dried urine spots. Research analysis of field samples from HIV prevention trials compared to research analysis of liquid urine will be discussed, as well as other potential opportunities and limitations of the methodology.
Which Chromatography and Mass Analyzer is Right for Your Clinical Research Application?
Lewis Couchman, Senior Clinical Scientist and Development Lead
Viapath Analytics, King's College Hospital, London
Wed., Feb. 24 8:00–9:00 a.m. (Breakfast) Mojave Room
Mass spectrometry has wide applicability in clinical research, especially when combined with modern chromatography and sample preparation. However, clinical research method development should remain application-centred, and ideally use a range of approaches to design a ‘fit-for-purpose’ methodology.
We will describe the applicability of turbulent flow chromatography, high-resolution, accurate mass (HRAM) LC-MS, and rapid quantitative analysis using triple quad mass analysers. The merits of each will be discussed using examples from clinical research methods.
Unless otherwise noted, all products are for research use only, not for use in diagnostic procedures.
Featured podium talk
|Scaling Discovery Proteomics to Large Lung Cancer Cohorts using Data Independent Acquisition
John Koomen, Moffit Cancer Center
Scott Peterman, Thermo Fisher Scientific
Thurs. Feb. 25 1:00–1:20 p.m. Madera Room
|Mindy Gao||Optimization of Derivatization Reaction Used in Sample Preparation Method in Analysis of Methylmalonic Acid in Plasma for Clinical Research||#56||22-Feb||7:00 p.m.|
|Susan DiPietro||Generation of a novel digestion protocol for enhanced proteome coverage||#13||22-Feb||7:00 p.m.|
|Sherry Gregory||Improved speed & reproducibility of protein digestion using novel sample preparation technology||#60||22-Feb||7:00 p.m.|
|Valerie Thibert||Direct Injection of Serum and Online Solid Phase Extraction for the Quantification of 35 Benzodiazepines and Metabolites by Liquid Chromatography MS/MS||#88||22-Feb||7:00 p.m.|
|Scott Peterman||Development of a Routine Hemoglobin Profiling Workflow||#45||22.Feb||7:00 p.m.|
|Reiko Kiyonami||Discovering diabetic lipid biomarker using HRAM LC-MS-MS approach on a high field Hybrid Quadrupole-Orbitrap Mass Spectrometer||#2||23-Feb||3:00 p.m.|
|Kristine Van Natta||Evaluation of a New Four-Channel LC and a Mass Spectrometer for Open-Access Analysis of Multiple Drug Classes in Clinical Research||#56||23-Feb||3:00 p.m.|
|Jason Lai||Multichannel Optimization of a New Four Channel HPLC with a Single Mass Spectrometer to Simplify Workflow Complexity and to Improve Throughput of LC-MS||#60||23-Feb||3:00 p.m.|
|Claudio De Nardi||Direct Injection of Serum and Online Solid Phase Extraction for the Quantification of Antidepressants by Liquid Chromatography Tandem Mass Spectrometry - See more at: http://www.thermoscientific.com/en/about-us/events/msacl-2016.html#sthash.PWAAnUMV.dpuf||#32||23-Feb||3:00 p.m.|
|Xiaolei Xie||Parallel Reaction Monitoring and Selected Reaction Monitoring Exhibit Comparable Quantitative Performance in Clinical Research and Forensic Applications||#58||23-Feb||3:00 p.m.|
|Anastasia Kalli||Quantitation of Antidepressant Drugs and their Metabolites by High-Resolution Mass Spectrometry Utilizing PRM and Full-MS Scan Modes for Forensic Research||#17||23-Feb||5:00 p.m.|
|Jia Wang||Evaluation of Automated Data Processing of Acylcarnitines and Amino Acids in Flow Injection Tandem Mass Spectrometry Analysis Using a Meta-calculation Software||#60||24-Feb||3:00 p.m.|
|Marta Kozak||Evaluation of novel solid phase micro extraction sample preparation method for LC-MS analysis of drugs of abuse in urine and plasma samples for forensics||#59||24-Feb||5:00 p.m.|
Routine clinical testing
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Clinical and translational research
We are committed to providing reliable and easy-to-use solutions, service, and support to help meet the demanding needs of clinical and translational research, from scalable translational research solutions to proven clinical laboratory services and diagnostics.