MIT Samberg Conference Center: Chang Building (E52)  | 50 Memorial Drive, Cambridge, MA 02142
Cryo-EM in Drug Discovery Scientific Symposium

Topics include:

  • Cryo-EM in Biopharma: Progress and Lessons Learned
  • Cryo-EM by Outsourcing: Panel Discussion
  • Bottlenecks: Sample preparation, Throughput, Data Infrastructure 
  • Hot Topics: micro-Electron Diffraction


Agenda (updated)

09:00–10:00 a.m. Registration  
10:00–10:50 a.m. Welcome and
Morning Keynote

Mark Stevenson,
Executive VP & COO, Thermo Fisher Scientific

Cathy Drennan,
Howard Hughes Medical Institute Professor at
Massachusetts Institute of Technology

MicroED: Conception, Practice, and Future Opportunities

Tamir Gonen,
Howard Hughes Medical Institute
University of California, Los Angeles
10:50–11:10 a.m. BREAK  
11:10–11:40 a.m. Session 1: CryoEM by Outsourcing Integrating the Glacios into the Astex EM Workflow

Pamela Williams,
Astex Pharmaceuticals
11:40–12:20 p.m.   Roundtable

Anette Schneemann,
Chief Scientific Officer
NanoImaging Services

Chen Xu,
Associate Professor
Department of Biochemistry and
Molecular Pharmacology and
Director of Cryo-Electron Microscopy Facility
Umass Medical School

Byron DeLaBarre,
Founder & Principal
The Consulting Biochemist, LLC

Ed Brignole,
Assistant Director,
CryoEM Center
12:20–1:50 p.m. LUNCH  
1:50–2:20 p.m. Session 2: Bottlenecks Identifying Drug Binding in Moderate to High-resolution CryoEM Maps

Craig Yoshioka,
Director of U24 CryoEM Facility
Oregon Health & Science University
2:20–2:50 p.m.   CryoEM Sample Prep for Drug Discovery: Optimization for Throughput and Resolution

Chris Arthur,
Principal System Specialist
2:50–3:10 p.m. BREAK  
3:10–3:40 p.m. Session 3: Lessons Learned Applications of Cryo-EM in Small Molecule and Biologics Drug Design

Seungil Han,
Associate Research Fellow,
Cryo-EM Labhead,
Structural & Molecular Sciences
Pfizer Inc, Groton
3:40–4:10 p.m.   CryoEM for Drug Discovery, Design, Understanding, and Application

Giovanna Scapin,
Sr. Principal Scientist,
Computational and Structural Chemistry
Merck & Co., Inc.
4:10–5:00 p.m. Evening Keynote Building Cryo-EM at Genentech to Enable Drug Discovery<

Claudio Ciferri,
Sr. Scientist and
Head of CryoEM
5:00–6:30 p.m. RECEPTION  

MIT Samberg Conference Center
Chang Building (E52)
50 Memorial Dr.
Cambridge, MA 02142



We have not reserved a block of rooms; however, the two nearest hotels are:

Organizing Committee

    Anke Mulder, Sr. Scientist at Thermo Fisher Scientific

    Ed Brignole, Assistant Director of Cryo-EM Facility at MIT

    Contact the organizers