"Ask The Expert" Webinar: Updating your Peptide Mapping and Glycan analysis for Therapeutic proteins | Available on-demand now!

Peptide mapping is a fundamental workflow that is required to ensure that the bio-therapeutics structural integrity is maintained at all stages of the drug development pipeline. This is required for the maintenance of drug efficacy and patient safety.

Current sample preparation techniques utilized for peptide mapping are complex, and prone to error, this can have a dramatic effect on reanalysis rates and method transfer across different sites. There is also the question of how the whole technique can be developed, especially in relation to Multi Attribute Monitoring of post translational modifications.

One of the important modifications is glycan characterization. The analysis of this modification can be done at the released, peptide and intact level. There are advantages to each analytical approach which can be related to the type of sample in question.

This webcast details how new technologies can deliver peptide mapping which is:

• Fast, Reproducible and precise
• Easy for untrained operators and automatable
• Provides high quality results with low Post Translational Modifications (PTMs)

Glycan Analysis which is:

• Driven from peptide mapping
• At the intact and middle up level
• Released and labeled Glycans using innovative column selectivity’s for different sample types

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