Fluid Transfer Solutions

Scalable fluid transfer solutions

Fluid transfer assemblies are critical components across the bioprocessing workflow. In the production of biologics, such as therapeutic proteins, fluid transfer facilitates various processes including cell culture media preparation, cell expansion, biologic harvest, purification, and fill-finish. Designed to manage large volumes safely and efficiently, these systems help streamline workflows while protecting product quality and reducing contamination risk.
 

Thermo Fisher Scientific provides a comprehensive selection of standard and customized fluid transfer products. Our offerings include the dependable and leakproof Thermo Scientific Nalgene fluid transfer tubing as part of our Thermo Scientific standard line of fluid transfer assemblies with the BioTitan Retention Device that connect to a variety of bioprocess bags and bottles. Additionally, many of our products can be easily configured using our Single-Use Assembly Configurator tool.

Optimize your processes with fluid transfer products

BioTitan Retention Device

The BioTitan Retention Device supports single-use fluid transfer assemblies with a secure 360-degree seal around tubing and fittings. As an innovative replacement for traditional cable ties, it helps mitigate the risk of leaks, simplify setup, and improve the reliability and integrity of bioprocessing workflows.

Design your single-use fluid transfer assembly


Our Single-Use Assembly Configurator Tool enables you to effortlessly design custom single-use fluid transfer assemblies or find in-stock, ready-to-ship products for faster lead times. Submitted designs are promptly reviewed, with quotations issued quickly. 3D rendered assembly images ensure your design meets your needs.
 

Customized fluid transfer solutions

We offer customized fluid transfer solutions designed specifically for the unique needs of your process. Leverage our solutions to help reduce the risk of sterility failure and save on sterilization costs. Supports “lean” systems by decreasing inventory, simplifying supply chains, and reducing labor costs.

Standard fluid transfer solutions

Experience fast lead times when leveraging standard products for your fluid transfer needs. In addition, we offer a large portfolio of stocked and ready to ship fluid transfer products to support your bioprocessing applications.
 

Frequently asked questions

Fluid transfer solutions for bioprocessing include single-use tubing, connectors, bags, bottles, containers, and assemblies that can integrate with bioreactors, mixers, and cell factories. Our solutions include the BioTitan Retention Device which is designed to form a 360-degree seal to prevent leaks.

There are many benefits of fluid transfer solutions including the reduction of leaks and spills reducing contamination risk. They provide consistency of handling and are particularly useful for the movement of fluids in and out of large or difficult to access vessels like bioreactors.

Fluid transfer solutions support closed system bioprocessing by offering sterile, leakproof connections that help minimize the risk of contamination. They enable easy integration with bioreactors, mixers, and other equipment. The BioTitan Retention Device helps improve the integrity of closed systems by forming a 360-degree seal around tubes and fittings.

Standard assemblies are stocked and can be ordered directly with relatively short lead times. We offer several types of custom assemblies that have different lead times. Some assemblies can be configured from in stock components using the Single-Use Assembly Configurator. More customized solutions can be made from components within our Global Standard Component Library (GSCL).

Explore related fluid management products

Bioprocessing bags

Bioprocess bags are single-use, sterile, ready-to-use fluid containers engineered for sterile liquid handling. Many options are available including 2D, 3D, and tank liners. Rigorously tested from integrity to leak analysis to minimize risks. Connections are secured with the BioTitan Retention Device to help prevent leaks.

Bioprocess bottles and carboys

Low and ultra-low particulate bottles and carboys are designed for optimal storage and transportation of biological and chemical solutions. Made from high-quality materials and available in various sizes, these containers are ideal for fluid transport. Also available in standard or custom assembly systems.
 

Cell factory systems

Easily scale your adherent cell cultures from flasks to Nunc High Density Cell Factory Systems. Available from single layers to 52 layers of surface to support expansion.  Use our fluid transfer solutions including filter assemblies, tubing, special caps, and connectors to create a closed system.
 

Production tanks and drums

Trusted, robust solutions for storing and transporting large volumes in many environments including bioprocessing. Available in a variety of shapes and sizes. Single-use tank liners are designed specifically to fit Nalgene and Thermo Scientific cylindrical tanks and drums, reducing the need for cleaning and speeding cycle times.

Made-to-stock bioprocess bags and tubing assemblies

In-stock and ready-to-ship high quality bioprocessing solutions. No need to sacrifice quality or change processes due to long lead times. We offer a broad portfolio of products to support diverse needs off‑the‑shelf and in‑region to significantly reduce lead times.

Our bags, containers and tubing assemblies are made from high‑quality Aegis film, with extremely low leak rates. To further reduce leak risk, our assemblies feature the BioTitan Retention Device, an innovative replacement to cable ties which forms a 360-degree seal.

Explore bioprocessing insights


The Bioprocessing Insights Hub by Thermo Fisher Scientific is designed for biomanufacturing professionals, offering educational resources to optimize single-use bioprocessing workflows. It features articles, guides, and case studies on topics such as assembly design, contamination mitigation, and technology transfer. Resources include application notes, brochures, white papers, videos, and webinars, covering areas like process optimization, scalability, quality, and sustainability.

For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.