Reliable solutions for every stage of therapeutic antibody development

 

In your efforts to discover, synthesize, characterize, and optimize antibody candidates, you need reliability. When you’re ready to scale up your manufacturing, you need consistency. We offer reliable, consistent, and innovative solutions for every stage of therapeutic antibody development, to help you ensure the quality and safety of your biologics.

From protein expression systems and immunoassays to bioreactors and plastics, we provide high performing reagents and full-process universal equipment and consumables to effectively minimize cross-contamination and maintain environmental stability. To help you ensure that a recombinant antibody is safe, effective, and accepted by regulatory authorities, we’re here for you with outstanding QA/QC services.

View our comprehensive list of products, services, and technologies to support you at every step of the therapeutic antibody development process.

Target discovery

Research into the biology and progression of a disease allows the identification and validation of druggable disease targets and their suitability for targeting with monoclonal antibody therapies.

Featured product

Genetic analysis

Immune repertoire with NGS

A rapid, long-read NGS tool for analyzing the immune repertoire to capture the diversity of T cell receptor (TCR) rearrangements.

Discover more 

Gene expression analysis using qPCR

Best-coverage assays to detect the highest number of transcript variants possible, with gold-standard specificity, sensitivity, and reproducibility.

Discover more

Gene knockout using CRISPR-Cas9

Advanced gRNA designs for maximum efficiency without sacrificing specificity; arrayed libraries in flexible formats for a wide variety of assays.

Discover more

Gene knockdown using siRNAs
 

Potent and specific siRNAs covering the druggable genome, with proprietary algorithm and chemical modifications.

Discover more

Gene expression analysis using RNA sequencing

From targeted gene expression analysis to whole-transcriptome sequencing, combine simple sample preparation and intuitive data analysis.

Discover more

Protein analysis

Mass spectrometry

Understand the functions of individual proteins and their place in complex biological systems with state-of-the-art proteomics mass spectrometry.

Discover more

Immunoassays

Investigate protein and RNA biomarkers in key disease research areas from single-analyte analysis using ELISA formats to multiplex bead-based assays.

Discover more

Protein–protein interaction assays

Characterize protein interactions through methods such as immunoprecipitation, yeast two-hybrid screening, phage display, and more.

Discover more

Protein structure analysis by cryo-electron microscopy

Generate complete structural information, uncover how antibodies function in the body, and show how they bind to antigens.

Discover more

pH measurements
 

Make your pH measurements of your buffers and reagents fast and reliable with an extensive range of meters, electrodes and accessories designed to work seamlessly together.

Discover more

Cell-based analysis

Regulatory T cells (Treg) analysis

Understand the role of regulatory T cells with reagents for expansion, differentiation and functional studies, and cytokine profiling.

Discover more

Cell function assays

A broad range of cell function and behavior assays and reagents that can be used on multiple instrument platforms.  

Discover more

Cell model creation

Closely mimic the in vivo state and generate more physiologically relevant data with complete cell culture systems for mAb discovery.

Discover more

Immune response analysis by flow cytometry

Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.

Discover more

Biological safety cabinets
 

Maximise sample protection and user safety, with an emphasis on containment, comfort and convenience, all day, every day.

Discover more

Antibody generation and engineering

Generate antibodies that bind to the target, then engineer to improve performance e.g., chimerization, humanization, manufacture of recombinant antibody fragments, bispecific antibodies, and antibody drug conjugates.

Featured product

Antigen production

Gene synthesis for expression-ready genes

Preparation of optimized synthetic, expression-ready genes for stable and increased protein expression or DNA immunization.

Discover more

Transient protein expression system
 

Rapidly produce high amounts of protein with integrated expression system solutions that give yield, speed, and cost benefits.

Discover more

Custom peptide synthesis services
 

Peptides synthesized using the latest FMOC solid-phase technology, and purified using HPLC.

Discover more

Antibody lead discovery & generation

Carrier protein immunogens and adjuvants

Immunization adjuvants are used to increase or stimulate immune response when mixed and injected with prepared immunogens.

Discover more

Serum-free hybridoma media
 

Chemically defined, protein-free formulation designed for maximum performance.

Discover more

Transient protein expression platforms
 

High-density, serum-free suspension culture and specially designed transfection reagents for the highest yields possible in a transient system.

Discover more

Phage display systems

High-quality magnetic beads with increased surface area for panning saturated phage solutions during phage display.    

Discover more

High-content screening

Platforms and software for cutting-edge images and high content imaging data in no time; exceptional resolution with subcellular, automated detection.

Discover more

CO2 incubators

You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.

Discover more

Antibody engineering

Gene synthesis for antibody DNA variant libraries

Create proteins with characteristics you need for affinity maturation; significantly reduce screening efforts compared to conventional mutagenesis.

Discover more

Antibody characterization

The evaluation of biological and molecular/structural characteristics during development and production. Multi-attribute methods based on a combination of peptide mapping and mass spectroscopy are increasingly being used.

Featured product

Biological characterization

Immunoassays

Matched antibody pairs, uncoated and coated-plate ELISA kits, and multiplexing assays for reliability and specificity during ligand binding studies.

Discover more

Cell function assays

Cell-based assays and reagents for key cellular processes, including apoptosis, cell proliferation, cell cycle and viability.  

Discover more

Biodistribution assays

A range of products for imaging biological processes in live animals to understand cellular activity, effects of drugs, and disease progression.

Discover more

Immune response analysis by flow cytometry

Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.

Discover more

Automated reagent dispensing
 

A new workflow solution to increase throughput, reproducibility, and speed through automated reagent dispensing into a wide selection of plate and volume ranges.

Discover more

Biophysical characterization

Protein or peptide quantitation

A broad range of protein or peptide quantitation assays for your sample type and application.

Discover more

Size heterogeneity analysis

SEC HPLC columns for monoclonal antibody, aggregate, and fractions separation.

Discover more

Peptide mapping

A unique combination of innovative technologies in a start-to-finish workflow that is designed to be fast, reliable, reproducible, and easy to use.

Discover more

Protein structure analysis with mass spectrometry

Obtain maximum insights on your most complex molecules and biological systems, from whole-proteome profiling and quantitation, structural characterization to multiplexed single-cell proteomics.

Discover more

Charge variant analysis
 

A range of buffers, ion exchange or hydrophobic interaction column chemistries, and UHPLC instrumentation to meet the needs for robust analysis of charge variants in monoclonal antibodies.

Discover more

Bioproduction and process development

Production of antibodies for clinical trials may include the use of alternative expression systems, continuous biomanufacturing systems, and non-chromatographic separation formats.

Featured product

Stable cell line and bioreactor production

Stable cell line development
 

Integrated stable cell line development solutions to simplify your development workflow and accelerate your processes to commercial manufacture.

Discover more

Cell culture media development and optimization

Optimize your media and processes for increased titers, quality, and manufacturability with our media development services.

Discover more

Bioreactor systems
 

Scalability from research to cGMP manufacturing with a comprehensive bioreactor portfolio.

Discover more

CO2 incubators

You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.

Discover more

Purification

Affinity chromatography resins
 

Resins designed specifically for the purification of antibody fragments and novel antibody formats.

Discover more

Bioprocess resins
 

For large scale manufacturing of biopharmaceuticals, high-performance and high-throughout resins.

Discover more

Hydrophobic interaction chromatography

A suite of resins suitable for bind/elute and flow-through applications; purify a wide variety of biomolecules at low salt concentrations.

Discover more

Impurity and contamination testing

Residual host-cell DNA quantitation

Complete solution for extraction and quantitation of DNA from biopharmaceutical purification sample matrices.

Discover more

Mycoplasma detection testing

Help ensure early detection of mycoplasma contamination and same day actionable results, with a sensitive real-time PCR based mycoplasma detection assay.

Discover more

Adventitious virus testing

Get accurate, rapid results from a system that is part of a total workflow solution and lessen your testing challenges in a GMP environment.

Discover more

Protein quantitation

An immuno-PCR based quantitation platform for sensitive and robust protein quantitation with a wide dynamic range.  

Discover more

Microbial identification

Rapid, accurate identification of thousands of bacterial and fungal species typically in under 5 hours.

Discover more

Purity test with SEC-HPLC

Separate biological molecules and polymers according to size using either SDS-PAGE / SEC-HPLC / capillary electrophoresis (reduced & nonreduced).

Discover more

Sample preparation

A universal, magnetic bead–based sample preparation technology for efficient sample clean-up for reproducible contaminant and impurity testing.

Discover more

Target discovery

Research into the biology and progression of a disease allows the identification and validation of druggable disease targets and their suitability for targeting with monoclonal antibody therapies.

Featured product

Genetic analysis

Immune repertoire with NGS

A rapid, long-read NGS tool for analyzing the immune repertoire to capture the diversity of T cell receptor (TCR) rearrangements.

Discover more 

Gene expression analysis using qPCR

Best-coverage assays to detect the highest number of transcript variants possible, with gold-standard specificity, sensitivity, and reproducibility.

Discover more

Gene knockout using CRISPR-Cas9

Advanced gRNA designs for maximum efficiency without sacrificing specificity; arrayed libraries in flexible formats for a wide variety of assays.

Discover more

Gene knockdown using siRNAs
 

Potent and specific siRNAs covering the druggable genome, with proprietary algorithm and chemical modifications.

Discover more

Gene expression analysis using RNA sequencing

From targeted gene expression analysis to whole-transcriptome sequencing, combine simple sample preparation and intuitive data analysis.

Discover more

Protein analysis

Mass spectrometry

Understand the functions of individual proteins and their place in complex biological systems with state-of-the-art proteomics mass spectrometry.

Discover more

Immunoassays

Investigate protein and RNA biomarkers in key disease research areas from single-analyte analysis using ELISA formats to multiplex bead-based assays.

Discover more

Protein–protein interaction assays

Characterize protein interactions through methods such as immunoprecipitation, yeast two-hybrid screening, phage display, and more.

Discover more

Protein structure analysis by cryo-electron microscopy

Generate complete structural information, uncover how antibodies function in the body, and show how they bind to antigens.

Discover more

pH measurements
 

Make your pH measurements of your buffers and reagents fast and reliable with an extensive range of meters, electrodes and accessories designed to work seamlessly together.

Discover more

Cell-based analysis

Regulatory T cells (Treg) analysis

Understand the role of regulatory T cells with reagents for expansion, differentiation and functional studies, and cytokine profiling.

Discover more

Cell function assays

A broad range of cell function and behavior assays and reagents that can be used on multiple instrument platforms.  

Discover more

Cell model creation

Closely mimic the in vivo state and generate more physiologically relevant data with complete cell culture systems for mAb discovery.

Discover more

Immune response analysis by flow cytometry

Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.

Discover more

Biological safety cabinets
 

Maximise sample protection and user safety, with an emphasis on containment, comfort and convenience, all day, every day.

Discover more

Antibody generation and engineering

Generate antibodies that bind to the target, then engineer to improve performance e.g., chimerization, humanization, manufacture of recombinant antibody fragments, bispecific antibodies, and antibody drug conjugates.

Featured product

Antigen production

Gene synthesis for expression-ready genes

Preparation of optimized synthetic, expression-ready genes for stable and increased protein expression or DNA immunization.

Discover more

Transient protein expression system
 

Rapidly produce high amounts of protein with integrated expression system solutions that give yield, speed, and cost benefits.

Discover more

Custom peptide synthesis services
 

Peptides synthesized using the latest FMOC solid-phase technology, and purified using HPLC.

Discover more

Antibody lead discovery & generation

Carrier protein immunogens and adjuvants

Immunization adjuvants are used to increase or stimulate immune response when mixed and injected with prepared immunogens.

Discover more

Serum-free hybridoma media
 

Chemically defined, protein-free formulation designed for maximum performance.

Discover more

Transient protein expression platforms
 

High-density, serum-free suspension culture and specially designed transfection reagents for the highest yields possible in a transient system.

Discover more

Phage display systems

High-quality magnetic beads with increased surface area for panning saturated phage solutions during phage display.    

Discover more

High-content screening

Platforms and software for cutting-edge images and high content imaging data in no time; exceptional resolution with subcellular, automated detection.

Discover more

CO2 incubators

You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.

Discover more

Antibody engineering

Gene synthesis for antibody DNA variant libraries

Create proteins with characteristics you need for affinity maturation; significantly reduce screening efforts compared to conventional mutagenesis.

Discover more

Antibody characterization

The evaluation of biological and molecular/structural characteristics during development and production. Multi-attribute methods based on a combination of peptide mapping and mass spectroscopy are increasingly being used.

Featured product

Biological characterization

Immunoassays

Matched antibody pairs, uncoated and coated-plate ELISA kits, and multiplexing assays for reliability and specificity during ligand binding studies.

Discover more

Cell function assays

Cell-based assays and reagents for key cellular processes, including apoptosis, cell proliferation, cell cycle and viability.  

Discover more

Biodistribution assays

A range of products for imaging biological processes in live animals to understand cellular activity, effects of drugs, and disease progression.

Discover more

Immune response analysis by flow cytometry

Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.

Discover more

Automated reagent dispensing
 

A new workflow solution to increase throughput, reproducibility, and speed through automated reagent dispensing into a wide selection of plate and volume ranges.

Discover more

Biophysical characterization

Protein or peptide quantitation

A broad range of protein or peptide quantitation assays for your sample type and application.

Discover more

Size heterogeneity analysis

SEC HPLC columns for monoclonal antibody, aggregate, and fractions separation.

Discover more

Peptide mapping

A unique combination of innovative technologies in a start-to-finish workflow that is designed to be fast, reliable, reproducible, and easy to use.

Discover more

Protein structure analysis with mass spectrometry

Obtain maximum insights on your most complex molecules and biological systems, from whole-proteome profiling and quantitation, structural characterization to multiplexed single-cell proteomics.

Discover more

Charge variant analysis
 

A range of buffers, ion exchange or hydrophobic interaction column chemistries, and UHPLC instrumentation to meet the needs for robust analysis of charge variants in monoclonal antibodies.

Discover more

Bioproduction and process development

Production of antibodies for clinical trials may include the use of alternative expression systems, continuous biomanufacturing systems, and non-chromatographic separation formats.

Featured product

Stable cell line and bioreactor production

Stable cell line development
 

Integrated stable cell line development solutions to simplify your development workflow and accelerate your processes to commercial manufacture.

Discover more

Cell culture media development and optimization

Optimize your media and processes for increased titers, quality, and manufacturability with our media development services.

Discover more

Bioreactor systems
 

Scalability from research to cGMP manufacturing with a comprehensive bioreactor portfolio.

Discover more

CO2 incubators

You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.

Discover more

Purification

Affinity chromatography resins
 

Resins designed specifically for the purification of antibody fragments and novel antibody formats.

Discover more

Bioprocess resins
 

For large scale manufacturing of biopharmaceuticals, high-performance and high-throughout resins.

Discover more

Hydrophobic interaction chromatography

A suite of resins suitable for bind/elute and flow-through applications; purify a wide variety of biomolecules at low salt concentrations.

Discover more

Impurity and contamination testing

Residual host-cell DNA quantitation

Complete solution for extraction and quantitation of DNA from biopharmaceutical purification sample matrices.

Discover more

Mycoplasma detection testing

Help ensure early detection of mycoplasma contamination and same day actionable results, with a sensitive real-time PCR based mycoplasma detection assay.

Discover more

Adventitious virus testing

Get accurate, rapid results from a system that is part of a total workflow solution and lessen your testing challenges in a GMP environment.

Discover more

Protein quantitation

An immuno-PCR based quantitation platform for sensitive and robust protein quantitation with a wide dynamic range.  

Discover more

Microbial identification

Rapid, accurate identification of thousands of bacterial and fungal species typically in under 5 hours.

Discover more

Purity test with SEC-HPLC

Separate biological molecules and polymers according to size using either SDS-PAGE / SEC-HPLC / capillary electrophoresis (reduced & nonreduced).

Discover more

Sample preparation

A universal, magnetic bead–based sample preparation technology for efficient sample clean-up for reproducible contaminant and impurity testing.

Discover more


Resources to streamline your therapeutic monoclonal antibody discovery and development

 

Style Sheet for Global Design System