We offer a broad selection of Thermo Scientific DNA ladders with fragment sizes ranging from 10 bp to 48.5 kb, for accurate analysis of linear double-stranded DNA in agarose or polyacrylamide gels. DNA ladders are manufactured and quality controlled to supersede industry standards. DNA ladders are made of chromatography-purified individual DNA fragments using a proprietary technology for preparation of pharmaceutical-grade plasmid DNA. DNA ladders are stable during prolonged incubation at room temperature and multiple freeze-thaw cycles.

GeneRuler and O'GeneRuler DNA Ladders

Ideal for sizing and approximate quantification of a wide range of double-stranded DNA. Supplied in standard and ready-to-use formats.

MassRuler DNA Ladders

Specially designed for accurate quantification and sizing of DNA fragments in agarose gels.

Lambda, Phage, and Plasmid DNA Markers

Conventional DNA molecular weight markers.

FastRuler DNA Ladders

Fast-separating ladders, designed for accurate sizing of double-stranded DNA (especially PCR products) in conventional, 48- or 96-well high-throughput gels.

Express DNA Ladders

Fast-separating versions of our popular ladders, designed for fast and accurate sizing under a range of electrophoresis conditions.

Loading Dyes, Agarose, and Buffers

Convenient reagents and buffers to achieve optimal electrophoresis results.

O’RangeRuler DNA Ladders

Step-ladders with exact repeats of a DNA fragment, designed for precise sizing of DNA in agarose or non-denaturing polyacrylamide gels.

NoLimits DNA Fragments

Individual, highly purified DNA fragments, useful for researchers wanting to create custom ladders.

Thermo Scientific DNA Ladder selection guide

  Range, bp Agarose gel resolution time Origin Formulation Loading dyes supplied
NoLimits Custom DNA Ladders 10-20,000 Composition dependent Individual, chromatography-purified DNA fragments In TE buffer or ready-to-use Any Thermo Scientific loading dye upon request
GeneRuler and O'GeneRuler DNA Ladders 10-48,502 10 min–1.5 hr Mixtures of individual, chromatography-purified DNA fragments In TE buffer or ready-to-use 6X DNA Loading Dye or 6X Orange Loading Dye
MassRuler DNA Ladders 80-10,000 10–45 min Mixtures of individual, chromatography-purified DNA fragments Ready-to-use 6X MassRuler Loading Dye
FastRuler DNA Ladders 10-10,000 8–14 min Mixtures of 5 individual, chromatography-purified DNA fragments Ready-to-use 6X MassRuler Loading Dye, 6X Orange Loading Dye
O'RangeRuler DNA Ladders 10-6,000 45 min–1.5 hr Ligated 5, 10, 15, 20, 50, 100, 200, 500 bp DNA fragments Ready-to-use 6X Orange Loading Dye
ZipRuler Express DNA Ladders 100-20,000 10–20 min Mixtures of individual, chromatography-purified DNA fragments Ready-to-use 6X Orange Loading Dye, 6X MassRuler Loading Dye
Conventional DNA Markers 8-23,130 45 min–18 hr Digested lambda, phage and plasmid DNA In TE buffer or ready-to-use 6X DNA Loading Dye