Thermo Scientific GeneRuler and O'GeneRuler DNA ladders are mixtures of chromatography-purified individual DNA fragments. The GeneRuler line includes the most popular ladders such as the 100 bp and 1 kb DNA Ladder.

GeneRuler DNA ladders are available in two formats: conventional (provided in TE buffer) and a ready-to-use format (premixed with 6X DNA Loading Dye which contains bromophenol blue and xylene cyanol FF). O'GeneRuler DNA ladders are another ready-to-use version of GeneRuler DNA ladders that are premixed with 6X Orange DNA Loading Dye.

GeneRuler 1 kb, 100 bp, and 50 bp DNA ladders

GeneRuler DNA Ladders are recommended for sizing and approximate quantification of a wide range of double-stranded DNA on agarose gels. Each ladder is a mixture of chromatography-purified individual DNA fragments. Available in ready-to-use format.

Features:

  • Universal ladders for DNA sizing and quantification—cover broad range of DNA molecular weights and provide DNA amount per band
  • Sharp bands, bright reference bands
  • Supplied with loading dye for sample DNA
  • Ready-to-use ladders are stable for 6 months at room temperature 

gel images of GeneRuler™ 1 kb, 100 bp, and 50 bp DNA ladders

GeneRuler 1 kb, 100 bp, and 50 bp DNA ladders selection guide

Range, bp DNA Ladder Quantity Cat. No.
50–1,000 GeneRuler 50 bp DNA Ladder 50 µg SM0371
5 x 50 µg SM0372
GeneRuler 50 bp DNA Ladder, ready-to-use 50 µg SM0373
100–1,000 GeneRuler 100 bp DNA Ladder 50 µg SM0241
5 x 50 µg SM0242
GeneRuler 100 bp DNA Ladder, ready-to-use 50 µg SM0243
5 x 50 µg SM0244
100–3,000 GeneRuler 100 bp Plus DNA Ladder 50 µg SM0321
5 x 50 µg SM0322
GeneRuler 100 bp Plus DNA Ladder, ready-to-use 50 µg SM0323
5 x 50 µg SM0324
250–10,000 GeneRuler 1 kb DNA Ladder 5 x 50 µg SM0311
25 x 50 µg SM0312
GeneRuler 1 kb DNA Ladder, ready-to-use 50 µg SM0314
5 x 50 µg SM0313
75–20,000 GeneRuler 1 kb Plus DNA Ladder 5 x 50 µg SM1331
25 x 50 µg SM1332
GeneRuler 1 kb Plus DNA Ladder, ready-to-use 5 x 50 µg SM1333
50 µg SM1334
100–10,000 GeneRuler DNA Ladder Mix 5 x 50 µg SM0331
25 x 50 µg SM0332
GeneRuler DNA Ladder Mix, ready-to-use 50 µg SM0334
5 x 50 µg SM0333

GeneRuler low and high range DNA ladders

GeneRuler DNA Low Range and High Range Ladders are best for sizing and approximate quantification of double-stranded DNA at low and high DNA size ranges. Each ladder consists of a mixture of chromatography-purified individual DNA fragments. Available in ready-to-use format.

Features:

  • Sizing and quantification at specific DNA molecular weight ranges
  • Sharp bands, bright reference bands
  • Supplied with loading dye for sample DNA
  • Ready–to-use ladders are stable for 6 months at room temperature

gel images of GeneRuler™ Low and High Range DNA Ladders

GeneRuler low and high range DNA ladders selection guide

Range, bp DNA Ladder Quantity Cat. No.
10–300 GeneRuler Ultra Low Range DNA Ladder 50 µg SM1211
5 x 50 µg SM1212
GeneRuler Ultra Low Range DNA Ladder, ready-to-use 50 µg SM1213
25–700 GeneRuler Low Range DNA Ladder 50 µg SM1191
5 x 50 µg SM1192
GeneRuler Low Range DNA Ladder, ready-to-use 50 µg SM1193
10,171–48,502 GeneRuler High Range DNA Ladder 50 µg SM1351
5 x 50 µg SM1352
GeneRuler High Range DNA Ladder, ready-to-use 50 µg SM1353

O’GeneRuler DNA ladders

O’GeneRuler DNA ladders are another ready-to-use version of GeneRuler DNA ladders. O’GeneRuler DNA ladders are premixed with 6X Orange DNA Loading Dye, which contains xylene cyanol FF and orange G. In a 1% agarose gel orange G dye migrates at 50 bp. Therefore O’GeneRuler DNA ladders are ideal to use  when visualization of small DNA fragments is important.

O'GeneRuler DNA ladder selection guide