In order to maintain cellular viability during the freezing process, certain cells require precise control of the freezing rate helping minimize the detrimental effects of undercooling and the heat liberated during the phase change process from water to ice. The Thermo Scientific CryoMed Controlled-Rate Freezers (CRFs) are designed with reliability, protection, and data traceability in mind for your sample preparation and GMP production needs. For customers in research, cell and gene therapy, vaccine production, and biobanking, the CryoMed CRF provides precise, repeatable freezing results that protect the sample from intracellular freezing.

Watch this video to learn more about the CyroMed CRF


Integrated OPC UA protocol within the new CryoMed CRF firmware to enable remote unit communication via DeltaV and other systems*.

  • OPC UA = Open Platform Communications United Architecture
  • OPC UA: Machine-to-machine communication protocol for industrial automation
  • DeltaV™: Distributed control system for automation systems

*OPC UA will open-up additional opportunities utilizing in-house automation and IT teams for integration with a data system.

CryoMed CRF with OPC UA - Equipment Package

product features

CryoMed consistent freezing results

Enhanced data traceability and customized freezing profiles for consistent temp. performance and real-time monitoring.

CTS documentation

Documentation package

CryoMed CRF with OPC UA comes equipped with a user manual, a certificate of conformance, and a certificate of calibration. 

Services flyer

Compliance services

Service options include installation qualification (IQ), operation qualification (OQ), and temperature mapping.

Choose your model and package

Medical Device (available in North America Only)

  • FDA listed Class II medical device, 510K exempt
  • Available in 17 L, 34 L, 48 L
  • With and without built-in thermal printer
  • 100V
  • 120V
  • 220-230V

General Purpose ( available everywhere)

  • Available in 17 L, 34 L, 48 L
  • With and without built-in thermal printer
  • 100V
  • 120V
  • 220-230V


Blog post

CryoMed Controlled-Rate Freezers that meet 21 CFR Part 11 requirements: Safeguarding sample integrity, traceability and 21 CFR Part 11 compliance.

Read more >


On-demand webinar

A Partnership in Data Traceability: 21 CFR part 11, the CryoMed controlled-rate freezer, and Your Lab/Production Processes

Watch on-demand >

Smart Note

Smart Note

How can the CryoMed CRF be used to prepare samples and therapies for long-term storage in a cryogenic storage device?

Read now >

Virtual tour: take a 3D tour and explore the CryoMed CRF

Cryomed 3D Tour

Note: This tool is best viewed in Chrome, Firefox or Safari Browsers. Learn more ›

Style Sheet for Global Design System
Style Sheet for Global Design System