Closed, scalable electroporation system for GMP-compliant cell therapy manufacturing

The CTS Xenon Electroporation System offers reliable delivery of DNA, RNA, proteins, and other molecules into cells, with exceptional cell viability and recovery. This leads to efficient transfection and genome editing, even in hard-to-transfect cells. A choice of two single-use electroporation chambers of different capacities provides flexibility: the SingleShot chamber enables process development while the MultiShot cartridge can be used in a closed, commercial-scale transfection system that minimizes contamination and human error while maximizing safety.


Process- and protocol-compatible with the Invitrogen Neon Transfection System, the Xenon system helps enable smooth scale-up from research to process development to commercial manufacturing of up to 25 mL at a time. Pair it with other Thermo Fisher Scientific instruments to assemble a closed, integrated, GMP-compliant workflow that can be controlled by process automation software.


Robust transfection

The Xenon Electroporation System offers reliably high transfection performance in volumes of up to 25 mL in less than 25 minutes with exceptional cell viability and recovery.

Closed system

Together, the Xenon Electroporation instrument, MultiShot cartridge, buffers, and software comprise a GMP-manufactured, closed cell electroporation system that minimizes contamination and maximizes safety.

Seamlessly scalable

Transition from research and early development on the small-scale Neon Transfection System (pictured) to process development and GMP manufacturing on the Xenon system using the same protocol without reoptimization.

Integrated workflow

The Xenon system can be integrated with other Thermo Fisher Scientific instruments and consumables into a complete, closed cell therapy manufacturing workflow.

Clinical manufacturing mode

Lock down protocols for commercial manufacturing and add electronic record-keeping software to enable FDA 21 CFR Part 11 compliance.


Intended use of the products mentioned on this page varies. For specific intended use statements, please refer to the product label.