Closed, scalable electroporator for large-scale nonviral delivery and GMP-compliant cell therapy manufacturing

The CTS Xenon Electroporation System offers reliable delivery of DNA, RNA, proteins, and other molecules into cells, with exceptional cell viability and recovery. This leads to efficient transfection and genome editing, even in hard-to-transfect cells.  A choice of two single-use electroporation chambers of different capacities provides flexibility: the CTS SingleShot chamber enables process development while the CTS MultiShot cartridge can be used in a closed, commercial-scale transfection system that helps minimize contamination and human error.


Process- and protocol-compatible with the Invitrogen Neon NxT Electroporation System, the CTS Xenon system enables scale-up from research to process development to commercial manufacturing of up to 25 mL at a time. Pair it with other Thermo Fisher Scientific instruments to assemble a closed, integrated, GMP-compliant workflow that can be controlled by process automation software.

CTS Xenon system capabilities

Robust transfection using the CTS Xenon electroporation instrument

The Xenon Electroporation System offers reliably high transfection performance in volumes of up to 25 mL in less than 25 minutes with exceptional cell viability and recovery.

Closed system for minimal contamination during the electroporation process

Together, the Xenon Electroporation instrument, MultiShot cartridge, buffers, and software comprise a GMP-manufactured, closed cell electroporation system that helps minimize contamination.

Scale from research to GMP manufacturing using the CTS Xenon electroporation instrument

Transition from research and early development on the small-scale Neon NxT Electroporation System (pictured) to process development and GMP manufacturing on the CTS Xenon system using the same starting protocols with minimal re-optimization.

Easy integration of the CTS Xenon system with other Thermo Fisher Scientific products

The CTS Xenon system can be integrated with other Thermo Fisher Scientific instruments and consumables into a complete, closed cell therapy manufacturing workflow.

Software to help enable 21 CFR part 11 compliance

Lock down protocols for commercial manufacturing and add electronic record-keeping software to enable FDA 21 CFR Part 11 compliance.