Flexible, scalable, closed cell processing system for cell therapy manufacturing.
Overview
The multipurpose Gibco CTS Rotea Counterflow Centrifugation System offers exceptional flexibility in a cell therapy development and manufacturing system. This versatile system applies the proven counterflow centrifugation method to a broad range of cell processing applications, such as CAR-T therapy, stem cell therapy, and PBMC isolation.
The CTS Rotea system consists of a compact multipurpose instrument, a sterile single-use kit, and intuitive, visual, customizable software. Together they constitute a closed system that offers exceptional cell recovery, flexible input and output volume capability, and high throughput. It’s ideal for multiple processes in your workflow, including cell separation, concentration, washing, buffer exchange, and cryopreservation. Highly concentrated outputs (with volumes as low as 5 mL) contain very little buffer or carryover, optimal for autologous cell therapy applications. The compact footprint, process flexibility, and closed, single-use kit allow the system to seamlessly scale with your process, from research through commercial manufacturing.
Capabilities
Compact multipurpose instrument
Operating on the principle of counterflow centrifugation elutriation, the Rotea process is gentle on cells, enabling over 95% cell recovery while maintaining viability and high throughput.
Closed single-use kit
The gamma-irradiated kit, which can be safely discarded when the process is complete, enables parallel processing in a Class C clean room.
Intuitive, visual software
An onboard protocol builder and simulation module help you develop and pilot-test your protocols before you try them on your samples. Use CellCam to monitor your cells visually through the isolation process and optimize settings in real time.
Exceptional process flexibility
The CTS Rotea system serves a variety of processes including cell separation, concentration, washing, buffer exchange, and cryopreservation. It fits on a benchtop and integrates smoothly at multiple points in your workflow.
Scales from R&D to manufacturing
Use the CTS Rotea system to develop and refine your processes. Then transition seamlessly and confidently to clinical GMP manufacturing using the same instrument, kits, and protocols.
World-class support
There’s no time for downtime in your lab. Our technical services, field engineering, and training teams are committed to ensure your success. We’ll even help you achieve regulatory compliance.
For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products.
