Clinical Research & Toxicology Peer-Reviewed Literature Library

Mass spectrometry-based discoveries in clinical and translational research

Thermo Fisher Scientific customers all over the world are using our instruments and other products to make critical progress in clinical application areas such as endocrinology, therapeutic drug monitoring, clinical biomarkers, translational research and forensics and toxicology. Click on the topics below to see related scientific publications in peer-reviewed journals.

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Toxicology, Quantitative Simultaneous quantification of 28 synthetic cathinones and metabolites in urine by liquid chromatography-high resolution mass spectrometry.synthetic cathinones, metabolitesHRAM MS
Toxicology, Quantitative Buprenorphine detection in urine using liquid chromatography-high-resolution mass spectrometry: comparison with cloned enzyme donor immunoassay (ThermoFisher) and homogeneous enzyme immunoassay (immunalysis).buprenorphineHRAM MS
Toxicology, Quantitative Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse.cytochrome P450HRAM MS
Toxicology, Quantitative Analysis of drugs of abuse by online SPE-LC high resolution mass spectrometry: communal assessment of consumption.drugs of abuseHRAM MS
Toxicology, Quantitative The use of turbulent flow chromatography for rapid, on-line analysis of tryptic digests.tryptic drugsHRAM MS
Toxicology, Quantitative Measurement of the Heterocyclic Amines 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Urine: Effects of Cigarette Smoking.heterocyclic amines 2-amino-9H-pyrido[2,3-b]indole, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, e-cigaretteTriple Quadrupole MS
Toxicology, Quantitative Rapid determination of nine barbiturates in human whole blood by liquid chromatography-tandem mass spectrometry.barbituratesTriple Quadrupole MS
Toxicology, Quantitative Liquid chromatography-high resolution-tandem mass spectrometry using Orbitrap technology for comprehensive screening to detect drugs and their metabolites in blood plasma.drugs, drug metabolitesHRAM MS
Toxicology, Quantitative Use of LC-HRMS in full scan-XIC mode for multi-analyte urine drug testing - a step towards a 'black-box' solution?psychoactive substances, NPSHRAM MS
Toxicology, Quantitative High-Throughput Screening and Quantitation of Target Compounds in Biofluids by Coated BladeSpray-Mass Spectrometry.anabolics, stimulants, diuretics, narcoticsTriple Quadrupole MS
Toxicology, Quantitative A liquid chromatography and tandem mass spectrometry method to determine 28 non-volatiledrugs of abuse in exhaled breath.drugs, volatile drugsTriple Quadrupole MS
Toxicology, Quantitative Dilute-and-shoot coupled to nanoflow liquid chromatography high resolution mass spectrometry for the determination of drugs of abuse and sport drugs in human urine.DOA, drugs of abuseHRAM MS
Toxicology, Quantitative Short-Term E-Cigarette Exposure Increases the Risk of Thrombogenesis and Enhances Platelet Function in Mice.e-cigaretteTriple Quadrupole MS
Toxicology, Quantitative Quantitative analysis of dextran in rat plasma using Q-Orbitrap mass spectrometry based on all ion fragmentation strategy.dextranHRAM MS
Toxicology, Quantitative A UHPLC-MS/MS method for the quantification of Δ9-tetrahydrocannabinol and cannabidiol in decoctions and in plasma samples for therapeutic monitoring of medical cannabis.THC, tetrahydrocannabinolTriple Quadrupole MS
Toxicology, Quantitative Adsorption of tobacco-specific nitrosamine 4- (methylnitrosamino) -1- (3-pyridyl)-1-butanone from aqueous solution with graphene aerogelnitrosamine; tobacco-specificTriple Quadrupole MS
Toxicology, Quantitative Oxytocin analysis from human serum, urine, and saliva by orbitrap liquid chromatography-mass spectrometry.oxytocin, fatty acyl, lipidsHRAM MS
Toxicology, Quantitative A liquid chromatography-tandem mass spectrometry platform for the routine therapeutic drug monitoring of 14 antibiotics: Application to critically ill pediatric patientsantibioticsTriple quadrupole MS
Toxicology, Quantitative Driving Under the Influence of Drugs: A Single Parallel Monitoring-Based Quantification Approach on Whole Blood22 DOAHRAM MS
Toxicology, Quantitative Flubromazolam-Derived Designer Benzodiazepines: Toxicokinetics and Analytical Toxicology of Clobromazolam and Bromazolamflubromazolam, designer benzodiazepineHRAM MS
Toxicology, Quantitative Simultaneous quantitative LC-MS method of ketamine, midazolam and their metabolites (dehydronorketamine, norketamine and 1hydroxymidazolam) for its application in patients on extracorporeal membrane oxygenation (ECMO) therapyketamine, midazolame, dehydronorketamine, norgetamine, metabolitesHRAM MS
Toxicology, Quantitative Paper spray screening and liquid chromatography/mass spectrometry confirmation for medication adherence testing: A two-step processantipsychoticHRAM MS
Toxicology, Quantitative Analysis for Alpha-Pyrrolidinovalerophenone and Its 2-Oxo-PVP Metabolite in Plasma by Liquid Chromatography-Tandem Mass SpectrometryAlpha-pyrrolidinovalerophenone (alpha-PVP)Triple Quadrupole MS
Toxicology, Quantitative Microfluidic filter device coupled mass spectrometry for rapid bacterial antimicrobial resistance analysisantibioticsIon Trap MS
Toxicology, Quantitative Drugs in bone: Detectability of substances of toxicological interest in different states of preservationDOAHRAM MS
Toxicology, Quantitative Development and validation of a LC-HRMS method for the quantification of cannabinoids and their metabolites in human plasmacannabinoids, cannabidiol, THCHRAM MS
Toxicology, Quantitative Development, validation, and application of a quantitative volumetric absorptive microsampling–based method in finger prick blood by means of LC-HRMS/MS applicable for adherence monitoring of antipsychoticsantipsychoticsHRAM MS
Toxicology, Quantitative Development, Validation, and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human PlasmaantipsychoticsHRAM MS
Toxicology, Quantitative Metabolism study and toxicological determination of mephtetramine in biological samples by liquid chromatography coupled with high-resolution mass spectrometrymephtetramineHRAM MS
Toxicology, Quantitative Method development for the identification of methoxpropamine, 2-fluoro-deschloroketamine and deschloroketamine and their main metabolites in blood and hair and forensic applicationmethoxpropamine, 2-fluoro-deschloroketamine and deschloroketamineHRAM MS
Toxicology, Screening Orbitrap technology for comprehensive metabolite-based liquid chromatographic-high resolution-tandem mass spectrometric urine drug screening - exemplified for cardiovascular drug screeningHRAM MS 
Toxicology, Screening Fully automated semi-quantitative toxicological screening in three biological matrices using turbulent flow chromatography/high resolution mass spectrometry.drugs of abuseHRAM MS
Toxicology, Screening First metabolic profile of PV8, a novel synthetic cathinone, in human hepatocytes and urine by high-resolution mass spectrometry.PV8, pyrrolidinophenone, drugs, novel psychoactive substances, NPSHRAM MS
Toxicology, Screening LC-HR-MS/MS standard urine screening approach: Pros and cons of automated on-line extraction by turbulent flow chromatography versus dilute-and-shoot and comparison with established urine precipitation.drugs, metabolitesHRAM MS
Toxicology, Screening Comprehensive analysis by liquid chromatography Q-Orbitrap mass spectrometry: Fast screening of peptides and organic molecules.peptides, organic compounds, DOAHRAM MS
Toxicology, Screening Development of a sensitive untargeted liquid chromatography-high resolution mass spectrometry screening devoted to hair analysis through a shared MS2 spectra database: A step toward early detection of new psychoactive substances.psychoactive substances, NPSHRAM MS
Toxicology, Screening Automated analysis of dried urine spot (DUS) samples for toxicology screening.DOA, drugs of abuseTriple quadrupole MS
Toxicology, Screening Characterization and tentative identification of new flunitrazepam metabolites in authentic human urine specimens using liquid chromatography-Q exactive-HF hybrid quadrupole-Orbitrap-mass spectrometry (LC-QE-HF-MS)flunitrazepam HRAM MS
Toxicology, Screening Detecting drugs in dry bone: a pilot study of skeletal remains with a post-mortem interval over 23 yearsdrugsHRAM GC-MS, HRAM MS
Toxicology, Screening Development and validation of liquid chromatography-tandem mass spectrometry targeted screening of 16 fentanyl analogs and U-47700 in hair: Application to 137 authentic samplesfentanyl analogsTriple quadrupole MS
Toxicology, Screening Development of a sensitive untargeted liquid chromatography– high resolution mass spectrometry screening devoted to hair analysis through a shared MS2 spectra database: A step toward early detection of new psychoactive substancesDOA, drugs of abuseHRAM MS
Toxicology, Screening Human urinary metabolic patterns of the designer benzodiazepines flubromazolam and pyrazolam studied by liquid chromatography-high resolution mass spectrometryflubromazolam, designer benzodiazepineHRAM MS
Toxicology, Screening LC-MS/MS and volumetric absorptive microsampling for quantitative bioanalysis of cathinone analogues in dried urine, plasma and oral fluid samples.cathinone analogues, microsamplingHRAM MS
Toxicology, Screening Liquid chromatography-high resolution mass spectrometry for broad-spectrum drug screening of dried blood spot as microsampling proceduredrugs of abuse, dried blood spotHRAM MS
Toxicology, Screening Detection of synthetic cannabinoid adulteration in the unregulated drug supply in three Canadian settingssynthetic cannabinoid adulterationHRAM MS
Toxicology, Screening Ultra-High Performance Liquid Chromatography-High Resolution Mass Spectrometry and High-Sensitivity Gas Chromatography-Mass Spectrometry Screening of Classic Drugs and New Psychoactive Substances and Metabolites in Urine of ConsumersDOAHRAM MS
Toxicology, Screening Development and validation of a method for quantification of human insulin and its synthetic analogues in plasma and post-mortem sera by LC-MS/HRMSinsulinHRAM MS
Translational research Individuality Normalization when Labeling with Isotopic Glycan Hydrazide Tags (INLIGHT): a novel glycan-relative quantification strategy.INLIGHT, isotope glycan hydrazide tagsHRAM MS
Translational research Comparison of SILAC and mTRAQ quantification for phosphoproteomics on a quadrupole orbitrap mass spectrometer.SILAC, mTRAQ, phosphoproteoomicsHRAM MS
Translational research Overcoming challenges and opening new opportunities in glycoproteomics.glycoproteomicsHRAM MS
Translational research Collagen peptides in urine: a new promising biomarker for the detection of colorectal liver metastases.peptidesHRAM MS
Translational research A direct-infusion- and HPLC-ESI-Orbitrap-MS approach for the characterization of intact PEGylated proteins.PEGylated proteinHRAM MS
Translational research Stable, reproducible, and automated capillary zone electrophoresis-tandem mass spectrometry system with an electrokinetically pumped sheath-flow nanospray interface.proteinsHRAM MS
Translational research Identification of potential serum biomarkers for rheumatoid arthritis by high-resolution quantitative proteomic analysis.proteomeHRAM MS
Translational research Deep proteomic profiling of human carotid atherosclerotic plaques using multidimensional LC-MS/MS.proteomeHRAM MS
Translational research Glycoform analysis of recombinant and human immunodeficiency virus envelope protein gp120 via higher energy collisional dissociation and spectral-aligning strategy.glycoform, protein gp120HRAM MS
Translational research Rapid and deep proteomes by faster sequencing on a benchtop quadrupole ultra-high-field Orbitrap mass spectrometer.proteomeHRAM MS
Translational research Using In-Solution Digestion, Peptide Fractionation, and a HRAM MS Mass Spectrometer to Analyze the Proteome of Clathrin-Coated Vesiclesproteome of clathrin-coated vesiclesHRAM MS
Translational research Urine sample preparation in 96-well filter plates to characterize inflammatory and infectious diseases of the urinary tract.proteinsHRAM MS
Translational research Comparative reevaluation of FASP and enhanced FASP methods by LC-MS/MS.proteinsHRAM MS
Translational research A Double-Barrel Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) System to Quantify 96 Interactomes per Day.proteomeHRAM MS
Translational research Quantification of cytokines secreted by primary human cells using multiple reaction monitoring: evaluation of analytical parameters.cytokinesHRAM MS
Translational research A novel and sensitive assay for heme oxygenase activityproteinTriple Quadrupole MS
Translational research Solid-phase extraction of small biologically active peptides on cartridges and microelution 96-well plates from human urinepeptidesTriple Quadrupole MS
Translational research Quantitative Site-Specific Phosphoproteomics of Trichoderma reesei Signaling Pathways upon Induction of Hydrolytic Enzyme Production.phosphoproteomicsHRAM MS
Translational research Implementation of Ultraviolet Photodissociation on a Benchtop HRAM MS Mass Spectrometer and Its Application to Phosphoproteomics.phosphoproteomicsHRAM MS
Translational research Selecting Optimal Peptides for Targeted Proteomic Experiments in Human Plasma Using In Vitro Synthesized Proteins as Analytical Standards.peptidesTriple Quadrupole MS
Translational research Constructing Proteome Reference Map of the Porcine Jejunal Cell Line (IPEC-J2) by Label-Free Mass Spectrometry.proteomeHRAM MS
Translational research Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays.peptidesTriple Quadrupole MS
Translational research Quantification of Human Kallikrein-Related Peptidases in Biological Fluids by Multiplatform Targeted Mass Spectrometry Assays.peptidase, human kallikrein-related peptidaseHRAM MS, Triple Quadrupole MS
Translational research Saliva-Induced Clotting Captures Streptococci: Novel Roles for Coagulation and Fibrinolysis in Host Defense and Immune Evasion.streptococci capturesHRAM MS, Triple Quadrupole MS
Translational research Quantitative Mass Spectrometry To Study Inflammatory Cartilage Degradation and Resulting Interactions with the Complement System.proteinsTriple Quadrupole MS
Translational research Minimum-noise production of translation factor eIF4G maps to a mechanistically determined optimal rate control window for protein synthesis.elF4GTriple Quadrupole MS
Translational research Longitudinal investigation of salivary proteomic profiles in the development of early childhood caries.peptidesHRAM MS
Translational research Exploring ECD on a Benchtop HRAM MS Orbitrap Mass Spectrometer.bottom-up proteomics, ECD utilityHRAM MS
Translational research Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach.proteins, brainTriple Quadrupole MS
Translational research Ultra-High-Resolution Mass Spectrometry for Identification of Closely Related Dermatophytes with Different Clinical Predilections.proteins, top-down, fungiHRAM MS
Translational research Targeted Mass Spectrometry-Based Assays for Relative Quantification of 30 Brain-Related Proteins and Their Clinical Applications.proteins, brainTriple Quadrupole MS
Translational research Impact of biological matrix on inflammatory protein biomarker quantification based on targeted mass spectrometry.proteomeTriple Quadrupole MS
Translational research Impact of biological matrix on inflammatory protein biomarker quantification based on targeted mass spectrometry.proteomeTriple Quadrupole MS
Translational research Acute Proteomic Changes in the Lung after WTLI in a Mouse Model: Identification of Potential Initiating Events for Delayed Effects of Acute Radiation Exposure.proteomeHRAM MS
Translational research iTRAQ plasma proteomics analysis for candidate biomarkers of type 2 incipient diabetic nephropathy.biomarkers, proteinsHRAM MS
Translational research DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discoveryproteins, peptidesHRAM MS
Translational research High-throughput, in-depth and estimated absolution quantification of plasma proteome using data-independent acquisition/ mass spectrometry ("HIAP-DIA")proteinHRAM MS
Translational research Integrating Serum Protein Electrophoresis with Mass Spectrometry, A New Workflow for M-Protein Detection and QuantificationM-proteinHRAM MS
Translational research Large-scale targeted metabolomics method for metabolite profiling of human samplesmetabolitesHRAM MS
Translational research Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and TransporterspeptidesHRAM MS
Translational research Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studiespeptidesHRAM MS
Translational research Vedolizumab quantitation using high-resolution accurate mass-mass spectrometry middle-up protein subunit: method validationvedolizumabHRAM MS
Translational research Critical comparison of three MS-based approaches for quantitative proteomics analysispeptidesHRAM MS
Translational research Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosislipids, PE, PC, LPEHRAM MS
Translational research Clinical Translation and Evaluation of a Handheld and Biocompatible Mass Spectrometry Probe for Surgical Usemetabolites, lipidsHRAM MS
Clinical research biomarkers Matrix-assisted laser desorption/ionization for simultaneous quantitation of (acyl-)carnitines and organic acids in dried blood spots.acylcarnitines, carnitines, organic acidsHRAM MS
Clinical research biomarkers An automated, high-throughput method for targeted quantification of intact insulin and its therapeutic analogs in human serum or plasma coupling mass spectrometric immunoassay with high resolution and accurate mass detection (MSIA-HR/AM).insulin, insuline analogsHRAM MS
Clinical research biomarkers Metabolomic profiling of anionic metabolites in head and neck cancer cells by capillary ion chromatography with Orbitrap mass spectrometry.anionic metabolitesHRAM MS
Clinical research biomarkers Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells.polo-like kinase 1, BI6727, Volasertib, BRAF, V600EHRAM MS
Clinical research biomarkers A strategy for sensitive, large scale quantitative metabolomics.metabolomicsHRAM MS
Clinical research biomarkers Proteomic and functional investigation of the colon cancer relapse-associated genes NOX4 and ITGA3.NOX4, ITGA3HRAM MS
Clinical research biomarkers Simultaneous quantification of Sphingolipids in small quantities of liver by LC-MS/MSsphingolipidsTriple Quadrupole MS
Clinical research biomarkers Underivatized oxysterols and nanoLC-ESI-MS: A mismatch.oxysterolsHRAM MS, Triple Quadrupole MS
Clinical research biomarkers Accurate and reliable quantification of 25-hydroxy-vitamin D species by liquid chromatography high-resolution tandem mass spectrometry.25-hydroxy vitamin DHRAM MS
Clinical research biomarkers Detection and quantification of proteins in clinical samples using high resolution mass spectrometry.protein, biomarkerHRAM MS
Clinical research biomarkers High speed capillary zone electrophoresis-mass spectrometry via an electrokinetically pumped sheath flow interface for rapid analysis of amino acids and a protein digest.amino acid, proteinsHRAM MS
Clinical research biomarkers Targeted Metabolomic Analysis of Head and Neck Cancer Cells Using High Performance Ion Chromatography Coupled with a HRAM MS HF Mass Spectrometer.targeted metabolomicsHRAM MS
Clinical research biomarkers MS2PIP prediction server: compute and visualize MS2 peak intensity predictions for CID and HCD fragmentation.prediction models for fragmentationHRAM MS
Clinical research biomarkers Analysis of Cell Metabolism Using LC-MS and Isotope Tracers.metabolismHRAM MS
Clinical research biomarkers Measurement of Lung Phosphatidylcholines in Exhaled Breath Particles by a Convenient Collection Procedure.phosphatidylcholinesTriple Quadrupole MS
Clinical research biomarkers Metabolism of human insulin after subcutaneous administration: A possible means to uncover insulin misuse.insulin, insulin metabolitesHRAM MS
Clinical research biomarkers Histamine quantification in human plasma using high resolution accurate mass LC-MS technology.histamineHRAM MS
Clinical research biomarkers Sensitive, Simple, and Robust Nano-Liquid Chromatography-Mass Spectrometry Method for Amyloid Protein Subtyping.amyloid proteinHRAM MS
Clinical research biomarkers Quantification of oxysterols in human plasma and red blood cells by liquid chromatography high-resolution tandem mass spectrometry.oxysterolsHRAM MS
Clinical research biomarkers In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant.α-pyrrolidinopentiothiophenoneHRAM MS
Clinical research biomarkers Altered Levels of Visinin-Like Protein 1 Correspond to Regional Neuronal Loss in AlzheimerDisease and Frontotemporal Lobar Degeneration.visinin-like proteinTriple Quadrupole MS
Clinical research biomarkers Development and Evaluation of a Parallel Reaction Monitoring Strategy for Large-Scale Targeted Metabolomics Quantification.metabolitesHRAM MS
Clinical research biomarkers Quantitation of a PEGylated protein in monkey serum by UHPLC-HRMS using a surrogate disulfide-containing peptide: A new approach to bioanalysis and in vivo stability evaluation of disulfide-rich protein therapeutics.PEGylated proteinHRAM MS
Clinical research biomarkers Dynamics of Protein Expression Reveals Primary Targets and Secondary Messengers of Estrogen Receptor Alpha Signaling in MCF-7 Breast Cancer Cells.protein, estrogen receptorHRAM MS, Triple Quadrupole MS
Clinical research biomarkers Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery.thromboxaneTriple Quadrupole MS
Clinical research biomarkers Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease.APOE, apolipoproteinTriple Quadrupole MS
Clinical research biomarkers Associations between calcium-phosphate metabolism and coronary artery calcification; a cross sectional study of a middle-aged general population.parathyroid hormone (PTH) and 25-hydroxyvitamin DTriple Quadrupole MS
Clinical research biomarkers Transfer of developmental neurotoxin β-N-methylamino-l-alanine (BMAA) via milk to nursed offspring: Studies by mass spectrometry and image analysis.BMAA, neurotoxinTriple Quadrupole MS
Clinical research biomarkers Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoringangiotensin II-regulated proteinsTriple Quadrupole MS
Clinical research biomarkers Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase.carboxyl ester lipase (CEL)Triple Quadrupole MS
Clinical research biomarkers An analytical strategy to investigate Semen Strychni nephrotoxicity based on simultaneous HILIC-ESI-MS/MS detection of Semen Strychni alkaloids, tyrosine and tyramine in HEK 293t cell lysates.semen strychini alkaloids, tyrosine, tyramineHRAM MS
Clinical research biomarkers Simultaneous Determination of Multiple Intracellular Primary Metabolites by Ultrahigh Performance Liquid Chromatography Coupled with a HRAM MS HF Mass Spectrometer.primary metabolitesHRAM MS
Clinical research biomarkers Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis.biomarkers, polar metabolites, lipidsHRAM MS
Clinical research biomarkers Oxidative stress leads to reduction of plasmalogen serving as a novel biomarker for systemic lupus erythematosus.plasmalogenTriple Quadrupole MS
Clinical research biomarkers 25C‐NBOMe and 25I‐NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high‐resolution mass spectrometry25C-NBOMe, 25I-NBOMeHRAM MS
Clinical research biomarkers Determination of amino acids in colon cancer cells by using UHPLC-MS/MS and [U-13C5]-glutamine as the isotope tracer.amino acidsTriple Quadrupole MS
Clinical research biomarkers Identification and Characterization of Cardiac Troponin T Fragments in Serum of Patients Suffering from Acute Myocardial Infarction.biomarker, cardiac troponin THRAM MS
Clinical research biomarkers Identification and quantitation of phosphatidylethanols in oral fluid by liquid chromatography-tandem mass spectrometry.phospatidylethanolTriple Quadrupole MS
Clinical research biomarkers A Nontargeted UHPLC-HRMS Metabolomics Pipeline for Metabolite Identification: Application to Cardiac Remote Ischemic Preconditioning.biomarkersHRAM MS
Clinical research biomarkers Expanding the knowledge on dried blood spots and LC-MS-based protein analysis: two different sampling materials and six protein targets.proteinHRAM MS, Triple Quadrupole MS
Clinical research biomarkers Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure.protein, biomarkerHRAM MS
Clinical research biomarkers Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.fructose 1,6-biphosphate, aldose mediate glucoseTriple Quadrupole MS
Clinical research biomarkers Quantification of xanthine- and uric acid-related compounds in urine using a "dilute-and-shoot" technique coupling ultra-high-performance liquid chromatography and high-resolution Orbitrap mass spectrometry.xanthine, uric acidHRAM MS
Clinical research biomarkers Holistic Lipidomics of the Human Gut Phenotype Using Validated Ultra-High-Performance Liquid Chromatography Coupled to Hybrid Orbitrap Mass Spectrometry.fatty acyls, glycerolipids, phosphoglycerolipids, polyketides, prenols, saccharolipids, sphingolipids, sterolsHRAM MS
Clinical research biomarkers Lower plasma choline levels are associated with sleepiness symptoms.cholineTriple Quadrupole MS
Clinical research biomarkers Intact Cell Assays to Monitor AMPK and Determine the Contribution of the AMP-Binding or ADaMSites to Activation.AMPKTriple Quadrupole MS
Clinical research biomarkers Easy, Fast, and Reproducible Quantification of Cholesterol and Other Lipids in Human Plasma by Combined High Resolution MSX and FTMS Analysis.cholesterol, glycerolipids, sphingolipids, sterol estersHRAM MS
Clinical research biomarkers Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.peptidesTriple Quadrupole MS
Clinical research biomarkers Amino acid and lipid associated plasma metabolomic patterns are related to healthspan indicators with ageing.amino acid, lipidTriple Quadrupole MS
Clinical research biomarkers Quantification of total dinutuximab concentrations in neuroblastoma patients with liquid chromatography tandem mass spectrometry.dinnutuximabTriple Quadrupole MS
Clinical research biomarkers N6-(2-Deoxy-d- erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5- N-(2-hydroxy-3-buten-1-yl)-formamidopyrimidine Adducts of 1,3-Butadiene: Synthesis, Structural Identification, and Detection in Human Cells.nucleobase adductsTriple Quadrupole MS
Clinical research biomarkers Rapid detection and quantification of aminoglycoside phosphorylation products using direct‐infusion high‐resolution and ultra‐high‐performance liquid chromatography/mass spectrometryaminoglycoside phosporylation productsHRAM MS
Clinical research biomarkers Neuronal pentraxin receptor-1 is a new cerebrospinal fluid biomarker of Alzheimer's disease progression.pentraxin receptorTriple Quadrupole MS
Clinical research biomarkers Total Fatty Acid Analysis of Human Blood Samples in One Minute by High-Resolution Mass Spectrometry.fatty acidsHRAM MS
Clinical research biomarkers Bioactive Lipids in Sputum of Older Adults with Asthma as Potential Markers of Disease PhenotypeslipidsTriple Quadrupole MS
Clinical research biomarkers How do cancer-sniffing dogs sort biological samples? Exploring case-control samples with non-targeted LC-Orbitrap, GC-MS, and immunochemistry methods.biomarkers, polar metabolites, lipidsHRAM MS
Clinical research biomarkers A validated multi-matrix platform for metabolomic fingerprinting of human urine, feces and plasma using ultra-high performance liquid-chromatography coupled to hybrid orbitrap high-resolution mass spectrometry.biomarkersHRAM MS
Clinical research biomarkers Rapid analysis of pyridinoline and deoxypyridinoline in biological samples by liquid chromatography-mass spectrometry and silica hydride column.pyridinoline, deoxypyridinolineHRAM MS
Clinical research biomarkers Performance of the MasSpec Pen for Rapid Diagnosis of Ovarian Cancer.lipidsHRAM MS
Clinical research biomarkers Plasma free metanephrines for diagnosis of neuroblastoma patients.metanephrines, plasma free metanephrinesTriple Quadrupole MS
Clinical research biomarkers Strain-Level Differentiation of Bacteria by Paper Spray Ionization Mass Spectrometry.bacteriaHRAM MS
Clinical research biomarkers Metabolomic profiling suggests systemic signatures of premature aging induced by Hutchinson-Gilford progeria syndrome.untargeted, amino acids, sphingolipids, fatty acidsHRAM MS, Triple Quadrupole MS
Clinical research biomarkers An Integrated Approach to Characterize Intestinal Metabolites of Four Phenylethanoid Glycosides and Intestinal Microbe-Mediated Antioxidant Activity Evaluation In Vitro Using UHPLC-Q-Exactive High-Resolution Mass Spectrometry and a 1,1-Diphenyl-2-picrylhydrazyl-Based Assay.biomarkersHRAM MS
Clinical research biomarkers Plasma metabolites Xanthine, 4-Pyridoxate, and d-glutamic acid as novel potential biomarkers for pulmonary tuberculosis.biomarkersHRAM MS
Clinical research biomarkers Comparative analysis of the serum proteome profiles of thyroid cancer: An initial focus on the lipid profile.proteomes, lipidsHRAM MS
Clinical research biomarkers Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass SpectrometryamatoxinsHRAM MS
Clinical research biomarkers Biomedical copper speciation in relation to Wilson's disease using strong anion exchange chromatography coupled to triple quadrupole inductively coupled plasma mass spectrometry.copper, ceruloplasminICP-MS
Clinical research biomarkers Characterization of a 7 kDa pollen allergen belonging to the gibberellin-regulated protein family from three Cupressaceae speciespollen allergenHRAM MS
Clinical research biomarkers Establishing reference intervals for urine and serum iodine levels: A nationwide multicenter study of a euthyroid Chinese population.iodineICP-MS
Clinical research biomarkers Evaluation of the first immunosuppressive drug assay available on a fully automated LC-MS/MS-based clinical analyzer suggests a new era in laboratory medicineimmunosuppressantsClinical Analyzer
Clinical research biomarkers High-precision isotopic analysis of serum and whole blood Cu, Fe and Zn to assess possible homeostasis alterations due to bariatric surgery.copper, iron, zincICP-MS
Clinical research biomarkers LC-HRMS based approach to identify novel sphingolipid biomarkers in breast cancer patientsspingolipidsHRAM MS
Clinical research biomarkers Metabolism Study of N-Methyl 2-amino Indane (NM2AI) and Determination of Metabolites in Biological Samples by LC-HRMSN-methyl-2-aminoindaneHRAM MS
Clinical research biomarkers Purity determination of synthetic glucagon using a mass balance approachglucagonHRAM MS
Clinical research biomarkers Simultaneous determination of gastric cancer biomarkers pepsinogen PGI/PGII using element tagged immunoassay coupled with inductively coupled plasma mass spectrometry detection.pepsinogen, element tagged immunoassayICP-MS
Clinical research biomarkers Simultaneous analysis of monosaccharides using ultra high performance liquid chromatography-high resolution mass spectrometry without derivatization for validation of certified reference materialsD-Ribose, L-Arabinose, D-Xylose, D-Fructose, D-Mannose, D-Galactose and D-GlucoseHRAM MS
Clinical research biomarkers Preliminary study procedure for detection of polyamines in plasma samples as a potential diagnostic tool in prostate cancerpolyaminesHRAM MS
Clinical research biomarkers High-sensitivity quantification of acetylcholine and choline in human cerebrospinal fluid with a validated LC-MS/MS methodcholine, acetylcholineTriple Quadrupole MS
Clinical research biomarkers Quantitative analysis of tryptophan and its metabolites in urine by ultra performance liquid chromatography-tandem mass spectrometrytryptophanTriple Quadrupole MS
Disease and disorders A multipronged deep omics-based investigation of COVID-19 plasma samples identifies key molecular networks of disease severity progressionCOVID-19HRAM MS
Disease and disorders Global N‐glycan site occupancy of HIV‐1 gp120 by metabolic engineering and high‐resolution intact mass spectrometry.HIVHRAM MS
Disease and disorders A novel function of IMPA2, plays a tumor-promoting role in cervical cancercancerHRAM MS
Disease and disorders A preliminary study procedure for detection of polyamines in plasma samples as a potential diagnostic tool in prostate cancerpolyaminesHRAM MS
Disease and disorders A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunityCOVID-19HRAM MS
Disease and disorders Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responsesCOVID-19HRAM MS
Disease and disorders Blood molecular markers associated with COVID‐19 immunopathology and multi‐organ damage. COVID-19HRAM MS
Disease and disorders Cellular Imprinting Proteomics Assay: A Novel Method for Detection of Neural and Ocular Disorders Applied to Congenital Zika Virus SyndromeZikaHRAM MS
Disease and disorders Cerebrospinal Fluid of Preeclamptic and Normotensive Pregnant Women Compared to Nonpregnant Women Analyzed with Mass SpectrometryproteinHRAM MS
Disease and disorders Detection of Head and Neck Cancer Based on Longitudinal Changes in Serum Protein Abundance AcancerHRAM MS
Disease and disorders Development and fit-for-purpose verification of an LC-MS method for quantitation of hemagglutinin and neuraminidase proteins in influenza virus-like particle vaccine candidatesinfluenzaHRAM MS
Disease and disorders Development of mass spectrometry-based targeted assay for direct detection of novel SARS-CoV-2 coronavirus from clinical specimensCOVID-19HRAM MS
Disease and disorders Elucidating Citrullination by Mass Spectrometry and Its Role in Disease Pathogenesisdisease pathogenesisHRAM MS
Disease and disorders Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohortsCOVID-19HRAM MS
Disease and disorders Evidence of Structural protein damage and membrane lipid remodeling in Red Blood Cells from COVID-19 patients COVID-19HRAM MS
Disease and disorders Exosomes in plasma for protein based cancer biomarkers: A clinical research tool using UHPLC-MSexosomesHRAM MS
Disease and disorders High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humanstuberculosisHRAM MS
Disease and disorders Identication of novel salivary candidate protein biomarkers for tuberculosis diagnosistuberculosisHRAM MS
Disease and disorders Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomicsCOVID-19HRAM MS
Disease and disorders Integration of metabolomics and transcriptomics reveals novel biomarkers in the blood for tuberculosis diagnosis in childrentuberculosisHRAM MS
Disease and disorders Late first trimester circulating microparticle proteins predict the risk of preeclampsia < 35 weeks and suggest phenotypic differences among affected casesexosomes, plasma, amnionic fluidHRAM MS
Disease and disorders LC/MS/MS-based quantitation of pig and human S100A1 protein in cardiac tissues: Application to gene therapycardiac diseaseHRAM MS
Disease and disorders Mass spectrometry-based absolute quantification of amyloid proteins in pathology tissue specimens: Merits and limitationsamyloid proteinHRAM MS, triple quadrupole MS
Disease and disorders Mechanism of succinate efflux upon reperfusion of the ischaemic heart cardiac diseaseHRAM MS
Disease and disorders Nanomedicine therapies modulating Macrophage Dysfunction: a potential strategy to attenuate Cytokine Storms in severe infectionsnanomedicineHRAM MS
Disease and disorders Proteomics as a tool for live attenuated influenza vaccine characterisationinfluenzaHRAM MS
Disease and disorders Proteomics of Select Neglected Tropical DiseasesDengueHRAM MS
Disease and disorders Proteotyping SARS-CoV‑2 Virus from Nasopharyngeal Swabs: A Proof-of-Concept Focused on a 3 Min Mass Spectrometry WindowCOVID-19HRAM MS
Disease and disorders Quantitative Proteomics of Human Heart Samples Collected In Vivo Reveal the Remodeled Protein Landscape of Dilated Left Atrium Without Atrial FibrillationproteinHRAM MS
Disease and disorders Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. COVID-19HRAM MS
Disease and disorders Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometryinsulin degludecHRAM MS
Disease and disorders Role of Multiomics Data to Understand Host–Pathogen Interactions in COVID-19 PathogenesisCOVID-19HRAM MS
Disease and disorders Shortlisting SARS-CoV-2 Peptides for Targeted Studies from Experimental Data-Dependent Acquisition Tandem Mass Spectrometry DataCOVID-19HRAM MS
Disease and disorders Simultaneous quantification of major capsid protein of human papillomavirus 16 and human papillomavirus 18 in multivalent human papillomavirus vaccines by liquid chromatography-tandem mass spectrometryHPVHRAM MS
Disease and disorders Specific and Rapid SARS-CoV-2 Identification Based on LC-MS/MS analysisCOVID-19HRAM MS
Disease and disorders Update on Proteomic approaches to uncovering virus-induced protein alterations and virus –host protein interactions during the progression of viral infectionH1N1HRAM MS
Disease and disorders Zika Infection Disrupts Proteins Involved in the Neurosensory SystemZikaHRAM MS
Disease and disorders Antibody to peptidoglycan recognition protein (PGLYRP)-2 as a novel biomarker in rheumatoid arthritisPGLYRPHRAM MS
Disease and disorders Protocols for Preparation and Mass Spectrometry Analysis of Clinical Urine Samples to Identify Candidate Biomarkers of Schistosoma-Associated Bladder Cancerproteins, peptidesHRAM MS
Disease and disorders Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's diseasepeptidesHRAM MS
Disease and disorders Quantitative proteomic analysis to identify differentially expressed proteins in patients with epilepsyproteomeHRAM MS
Disease and disorders Serum proteome signature to predict mortality in severe COVID-19 patientsSARS CoV-2HRAM MS
Disease and disorders Determination of amanita peptide toxins in human urine by TurboFlow online clean-up-liquid chromatography-tandem mass spectrometryamantia peptide toxins, TurboFlowHRAM MS
Disease and disorders Mass spectrometry-based targeted assay for detection of SARS-CoV-2 antigen from clinical specimensSARS CoV-2HRAM MS
Disease and disorders Accurate Identification of Closely Related Mycobacterium tuberculosis Complex Species by High Resolution Tandem Mass SpectrometryproteoformsHRAM MS
Disease and disorders Primary angle closure glaucoma is characterized by altered extracellular matrix homeostasis in the irispeptidesHRAM MS
Endocrinology An optimized method for neurotransmitters and their metabolites analysis in mouse hypothalamus by high performance liquid chromatography-Q Exactive hybrid quadrupole-orbitrap high-resolution accurate mass spectrometry.neurotransmitters, hypothalamus, neurotransmitter metabolitesHRAM MS
Endocrinology Simultaneous quantification of neuroactive dopamine serotonin and kynurenine pathway metabolites in gender-specific youth urine by ultra performance liquid chromatography tandem high resolution mass spectrometry.dopamine, serotonin, kynurenine pathway metabolitesHRAM MS
Endocrinology Resveratrol inhibits steroidogenesis in human fetal adrenocortical cells at the end of first trimester.resveratrol effects on steroidogenesisTriple Quadrupole MS
Endocrinology Quantification of steroid hormones in human serum by liquid chromatography-high resolution tandem mass spectrometry.steroid hormonesHRAM MS
Endocrinology Comparative limitations and benefits of liquid chromatography - mass spectrometry techniques for analysis of sex steroids in tears.steroidsHRAM MS
Endocrinology A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids.progestins, steroidsHRAM MS
Endocrinology Evaluation of the 25-hydroxy vitamin D assay on a fully automated liquid chromatography mass spectrometry system, the Thermo Scientific Cascadion SM Clinical Analyzer with the Cascadion 25-hydroxy vitamin D assay in a routine clinical laboratory.25-hydroxy vitamin DClinical Analyzer
Endocrinology Simultaneous quantification of fat-soluble vitamins A, 25-hydroxylvitamin D and vitamin E in plasma from children using liquid chromatography coupled to Orbitrap mass spectrometryVitamin A, D, EHRAM MS
Therapeutic drug monitoring Quantification of teicoplanin in plasma by LC-MS with online sample clean-up and comparison with QMS assay.teicoplaninHRAM MS
Therapeutic drug monitoring The development and validation of a method using high-resolution mass spectrometry (HRMS) for the qualitative detection of antiretroviral agents in human blood.antiretroviral drugs, HIV drugsHRAM MS
Therapeutic drug monitoring Assessment of tandem mass spectrometry and high-resolution mass spectrometry for the analysis of bupivacaine in plasma.bupivacaineTriple Quadrupole MS, HRAM MS
Therapeutic drug monitoring A high-resolution accurate mass (HR/AM) approach to identification, profiling and characterization of in vitro nefazodone metabolites using a hybrid quadrupole Orbitrap (Q-Exactive).nefazodone metabolitesHRAM MS
Therapeutic drug monitoring Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry.acetomenophen, alicylic acidHRAM MS
Therapeutic drug monitoring Quantification of active infliximab in human serum with liquid chromatography–tandem mass spectrometry using a tumor necrosis factor alpha -based pre-analytical sample purification and a stable isotopic labeled infliximab bio-similar as internal standard:infliximabTriple Quadrupole MS
Therapeutic drug monitoring Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide.phenobarbital, phenytoin, carbamazepineHRAM MS
Therapeutic drug monitoring Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation.drugs, antihypertensiveHRAM MS
Therapeutic drug monitoring Development and validation of an LC-MS/MS assay for the quantification of efavirenz in different biological matrices.efavirenzTriple Quadrupole MS
Therapeutic drug monitoring Development of a Simple and Rapid Method to Measure the Free Fraction of Tacrolimus in Plasma Using Ultrafiltration and LC-MS/MS.tacrolimus, immunosuppressantTriple Quadrupole MS
Therapeutic drug monitoring Quantitative proteomic analysis of HER2 expression in the selection of gastric cancer patients for trastuzumab treatment.trastuzumabTriple Quadrupole MS
Therapeutic drug monitoring Dried blood spot validation of five immunosuppressants, without hematocrit correction, on two LC-MS/MS systems.tacrolimus, sirolumus, everolimus, cyclosporin A, mycophenolic acidTriple Quadrupole MS
Therapeutic drug monitoring Ultra-fast quantitation of voriconazole in human plasma by coated blade spray mass spectrometry.voriconazoleTriple Quadrupole MS
Therapeutic drug monitoring LC-MS/MS quantification of free and Fab-bound colchicine in plasma, urine and organs following colchicine administration and colchicine-specific Fab fragments treatment in Göttingen minipigs.Fab-bound colchicine, Fab fragmentsTriple Quadrupole MS
Therapeutic drug monitoring Determination of voriconazole in aqueous humor by liquid chromatography-electrospray ionization-mass spectrometry.voriconazoleTriple Quadrupole MS
Therapeutic drug monitoring Characterization of metabolites of larotaxel in rat by liquid chromatography coupled with Qexactive high-resolution benchtop quadrupole orbitrap mass spectrometer.larotaxelHRAM MS
Therapeutic drug monitoring Human urinary metabolic patterns of the designer benzodiazepines flubromazolam and pyrazolam studied by liquid chromatography-high resolution mass spectrometry.benzodiazepines flubromazolam, pyrazolamHRAM MS
Therapeutic drug monitoring Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS).ISD, immunosuppressive drugsTriple Quadrupole MS
Therapeutic drug monitoring Development and validation of a liquid chromatography/tandem mass spectrometry method for determination of caspofungin in dried blood spots.capsofunginTriple Quadrupole MS
Therapeutic drug monitoring Development and validation of a targeted affinity-enrichment and LC-MS/MS proteomics approach for the therapeutic monitoring of adalimumab.adalimumabHRAM MS
Therapeutic drug monitoring An LC-MS/MS method for quantification of daptomycin in dried blood spot: Application to a pharmacokinetics study in critically ill patientsdaptomycinTriple Quadrupole MS
Therapeutic drug monitoring Simultaneous quantitation of five triazole anti-fungal agents by paper spray-mass spectrometryantifungalsPaperSpray Triple quadrupole MS
Therapeutic drug monitoring Validation of an HPLC-MS/MS Method for the Determination of Plasma Ticagrelor and its Active Metabolite Useful for Research and Clinical PracticeTicagrelor, Ticagrelor metaboliteTriple Quadrupole MS
Therapeutic drug monitoring Validation of a novel UPLC-HRMS method for human whole-blood cyclosporine and comparison with a CMIA immunoassayimmunosuppressantsHRAM MS
Therapeutic drug monitoring Analysis of Pembrolizumab in Human Plasma by LC-MS/HRMS. Method Validation and Comparison with ElisaPembrolizumabHRAM MS
Orthogonal techniques, Gas chromatography Development of a HS-SPME/GC–MS method for the analysis of volatile organic compounds from fabrics for forensic reconstruction applicationsVOCs for forensic useHRAM GC-MS
Orthogonal techniques, Gas chromatography Non-targeted acquisition strategy for screening doping compounds based on GC-EI-hybrid quadrupole-Orbitrap mass spectrometry: focus on exogenous anabolic steroidsanabolic steroidsHRAM GC-MS
Orthogonal techniques, Gas chromatography Development of a high-throughput screening analysis for 288 drugs and poisons in human blood using Orbitrap technology with gas chromatography-high resolution accurate mass spectrometry.drugs, poisonsHRAM GC-MS
Orthogonal techniques, Gas chromatography Using gas chromatography and mass spectrometry to determine 25-hydroxyvitamin D levels for clinical assessment of vitamin D deficiency.25-hydroxyvitamin DGC-MS/MS
Orthogonal techniques, Multiplexing UPLC–MS/MS method for the simultaneous quantification of bictegravir and 13 others antiretroviral drugs plus cobicistat and ritonavir boosters in human plasmaantiretroviral drugsLC-MS/MS
Orthogonal techniques, Multiplexing UPLC–MS/MS method for the simultaneous quantification of bictegravir and 13 others antiretroviral drugs plus cobicistat and ritonavir boosters in human plasmaimmunosuppressantLC-MS/MS
Orthogonal techniques, Multiplexing An automated, high-throughput method for targeted quantification of intact insulin and its therapeutic analogs in human serum or plasma coupling mass spectrometric immunoassay with high resolution and accurate mass detection (MSIA-HR/AM).insulin, insulin analogsHRAM MS
Orthogonal techniques, Multiplexing Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays.peptidesTriple Quadrupole MS
Orthogonal techniques, Multiplexing Quantification of Human Kallikrein-Related Peptidases in Biological Fluids by Multiplatform Targeted Mass Spectrometry Assays.peptidaseTriple Quadrupole MS
Orthogonal techniques, Multiplexing Targeted Mass Spectrometry-Based Assays for Relative Quantification of 30 Brain-Related Proteins and Their Clinical Applications.proteinsTriple Quadrupole MS
Orthogonal techniques, Paper spray Paper spray ionization mass spectrometry: recent advances and clinical applications.reviewHRAM MS and Triple Quadrupole MS
Orthogonal techniques, Paper spray Rapid analysis of fentanyls and other novel psychoactive substances in substance use disorder patient urine using paper spray mass spectrometry.fentanylsHRAM MS
Orthogonal techniques, Paper spray Paper Spray Ionization Coupled to High Resolution Tandem Mass Spectrometry for Comprehensive Urine Drug Testing in Comparison to Liquid Chromatography-Coupled Techniques after Urine Precipitation or Dried Urine Spot Workup.drugs of abuseHRAM MS
Orthogonal techniques, ICP-MS Sensitive determination of the human epidermal growth factor receptor 2 (HER2) by immuno-polymerase chain reaction with inductively coupled plasma-mass spectrometry detectionHER2ICP-MS
Orthogonal techniques, ICP-MS A comparison of sample preparation strategies for biological tissues and subsequent trace element analysis using LA-ICP-MStrace elementsICP-MS
Orthogonal techniques, ICP-MS Rapid inductively coupled plasma mass spectrometry method to determine iodine in amniotic fluid, breast milk and cerebrospinal fluid.iodineICP-MS
Orthogonal techniques, ICP-MS Simultaneous determination of gastric cancer biomarkers pepsinogen PGI/PGII using element tagged immunoassay coupled with inductively coupled plasma mass spectrometry detection.pepsinogen, element tagged immunoassayICP-MS
Orthogonal techniques, ICP-MS Biomedical copper speciation in relation to Wilson's disease using strong anion exchange chromatography coupled to triple quadrupole inductively coupled plasma mass spectrometry.copper, sulfur, phosphorus, ironICP-MS
Orthogonal techniques, ICP-MS Establishing reference intervals for urine and serum iodine levels: A nationwide multicenter study of a euthyroid Chinese population.iodineICP-MS
Orthogonal techniques, ICP-MS High-precision isotopic analysis of serum and whole blood Cu, Fe and Zn to assess possible homeostasis alterations due to bariatric surgery.copperICP-MS
Orthogonal techniques, ICP-MS Blood and plasma titanium levels associated with well-functioning hip implants.titaniumICP-MS
Orthogonal techniques, ICP-MS Sensitive determination of the human epidermal growth factor receptor 2 (HER2) by immuno-polymerase chain reaction with inductively coupled plasma-mass spectrometry detection.HER2ICP-MS
Orthogonal techniques, ICP-MS Evaluation of trace metals in thyroid tissues: Comparative analysis with benign and malignant thyroid diseases.trace elementsICP-MS
Orthogonal techniques, ICP-MS Cadmium as main endocrine disruptor in papillary thyroid carcinoma and the significance of Cd/Se ratio for thyroid tissue pathophysiology.cadmium, seleniumICP-MS
Orthogonal techniques, ICP-MS Validation of a simple inductively coupled plasma mass spectrometry method for detecting urine and serum iodine and evaluation of iodine status of pregnant women in Beijing.iodineICP-MS
Orthogonal techniques, ICP-MS Whole blood selenium determination by inductively coupled plasma mass spectrometry.seleniumICP-MS
Orthogonal techniques, ICP-MS Quantification of multiple elements in dried blood spot samples.trace elementsICP-MS
Orthogonal techniques, ICP-MS Urinary chromium is associated with changes in leukocyte miRNA expression in obese subjects.chromiumICP-MS
Orthogonal techniques, ICP-MS Metallic Profile of Whole Blood and Plasma in a Series of 99 Healthy Children.trace elementsICP-MS
Orthogonal techniques, ICP-MS Determination of Thirteen Trace and Toxic Elements in Urine Using Inductively Coupled Mass Spectrometry.trace elementsICP-MS
Orthogonal techniques, ICP-MS Evaluation of an Element-Tagged Duplex Immunoassay Coupled with Inductively Coupled Plasma Mass Spectrometry Detection: A Further Study for the Application of the New Assay in Clinical LaboratoryCEA, AFP, α-fetoproteinICP-MS
Orthogonal techniques, ICP-MS Rapid inductively coupled plasma mass spectrometry method to determine iodine in amniotic fluid, breast milk and cerebrospinal fluid.iodineICP-MS
Orthogonal techniques, Ion chromatography Purity determination of synthetic glucagon using a mass balance approachglucagon and impurtieiesHRAM IC-MS
Orthogonal techniques, Ion chromatography Metabolomic profiling of anionic metabolites in head and neck cancer cells by capillary ion chromatography with Orbitrap mass spectrometry.anionic metabolitesHRAM IC-MS
Orthogonal techniques, Ion chromatography An improved reference method for serum cations measurement by ion chromatography.cationsIC
Orthogonal techniques, Ion chromatography Use of Ion Chromatography/Mass Spectrometry for Targeted Metabolite Profiling of Polar Organic acidsIC-MS/MS
Orthogonal techniques, Dried matrix spots A novel LC-MS/MS assay for vitamin B 1, B 2 and B 6 determination in dried blood spots and its application in childrenvitamin B1, B2, B6, dried blood spotHRAM MS
Orthogonal techniques, Dried matrix spots Analysis of cyclosporin A in dried blood spots using liquid chromatography tandem mass spectrometrycyclosporin A, dried blood spotHRAM MS
Orthogonal techniques, Dried matrix spots Automated Analysis of Dried Urine Spot (DUS) Samples for Toxicology Screeningdrugs of abuse, dried urine spotHRAM MS
Orthogonal techniques, Dried matrix spots State of Science in Dried Blood Spotsdried blood spotsHRAM MS
Orthogonal techniques, Dried matrix spots Feasibility of Patient-Centric Remote Dried Blood Sampling: The Prediction, Risk, and Evaluation of Major Adverse Cardiac Events (PRE-MACE) Studycardiac disease, dried blood spotHRAM MS
Orthogonal techniques, Dried matrix spots Power of Orbitrap‐based LC‐high resolution‐MS/MS for comprehensive drug testing in urine with or without conjugate cleavage or using dried urine spots after on‐spot cleavage in comparison to established LC–MSn or GC–MS proceduresdrugs of abuse, dried urine spotHRAM MS
Orthogonal techniques, Quantitative New quantitative drug checking technology for harm reduction: Pilot study in Vancouver, Canada using paper spray mass spectrometryetizolam, fentanylTriple Quadrupole MS
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