Over seven million samples analyzed to date—and growing

Combining the power of the QuantStudio 12K Flex Real-time PCR System with qualified TaqMan genotyping assays, this solution delivers a sample-to-answer workflow that allows you to introduce pharmacogenomic testing into your laboratory with ease.


Thermo Fisher Scientific PCR PGx solutions: Features and benefits
 

Features include:

  • Fully qualified content—all TaqMan SNP Genotyping Assays have been tested against genomic DNA and synthetic controls
  • Express Panels include our most popular PGx content including—CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A5, SLCO1B1, VKORC1, COMT, OPRM1, DRD2, FII, FV, MTHFR, APOE2, APOE4
  • Flexible formats—our PGx solution has been optimized for anything from custom content to fit your needs, to off-the shelf content
  • Extensive menu of targets—over 2,700 TaqMan SNP Genotyping Assays available, targeting the most common drug metabolizing enzyme (DME) markers (including CYP2D6, CYP2C9, CYP4F2, and more)
  • Calling and reporting solutions—TaqMan Genotyper Software and AlleleTyper Software are available* to quickly and easily determine haplotypes of samples using star-allele nomenclature
  • Utilizing familiar instruments—our PGx solutions can be run on either QuantStudio 5 or QuantStudio 7 for custom plates, and QuantStudio 12K Flex System for OpenArray

*Additional PGx data and support files at bottom of page

 TaqMan OpenArray (OA)TaqMan Array Plates (TAP)
Focus

For mid-higher throughput applications

For low-mid throughput applications

Targets

TaqMan OpenArray PGx Express – 60:

  • 48 samples/plate
  • 60 pre-selected TaqMan PGx Assays

32 assays x 12 samples: 80 plates

64 assays x 6 samples: 160 plates

128 assays x 3 samples: 320 plates

Goals/needs
  • Customers who need between 48–120 markers
  • Genotyping of DME
  • Customers who need between 12–60 markers
  • Seamless, streamlined genotyping and Copy Number Variation (CNV) in single workflow
  • Less waste
Format

Off-the-Shelf and Custom

2,880 reactions with pre-spotted assays

4-hour workflow

Off-the-Shelf and Custom

384-well plates with pre-spotted assays

PGx Express (60) on 384-well plates

3-hour workflow

Compatible instrumentsQuantStudio 12K Flex Real-Time PCR System with OpenArray block

QuantStudio 12K Flex with 384-well block

QuantStudio 7 Flex & 7 Pro with 384-well block

QuantStudio 6 Flex & 6 Pro with 384-well block

QuantStudio 5 with 384-well block

Product

Unit Size

Catalog Number

Ordering information

TaqMan™ OpenArray™ Genotyping Master Mix

1 kit

4404846

Click to view

TaqMan™ Genotyping Master Mix

Sizes vary

Multiple SKUs

Click to view

TaqPath™ ProAmp™ Master Mix

Sizes vary

Multiple SKUs

Click to view


Workflow
 

We offer a simple, efficient workflow designed to maximize results.

Buccal swab, saliva, or blood

Thermo Scientific™ KingFisher™ Flex system with Applied Biosystems™ MagMAX™ DNA Multi-Sample Ultra Kit

Applied Biosystems™ OpenArray™ AccuFill™ System

Applied Biosystems™ QuantStudio™ 12K Flex Real-Time PCR System

Drug metabolism enzyme (DME) assays run on OpenArray plates or 384-well plates

Genotyping data: In-house laboratory information systems (LIS) or relative quantification application

Buccal swab, saliva, or blood

Thermo Scientific™ KingFisher™ Flex system with Applied Biosystems™ MagMAX™ DNA Multi-Sample Ultra Kit

Applied Biosystems™ OpenArray™ AccuFill™ System

Applied Biosystems™ QuantStudio™ 12K Flex Real-Time PCR System

Drug metabolism enzyme (DME) assays run on OpenArray plates or 384-well plates

Genotyping data: In-house laboratory information systems (LIS) or relative quantification application

Resources
 

For Research Use Only. Not for use in diagnostic procedures.

Style Sheet for Global Design System
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