Over seven million samples analyzed to date—and growing

Combining the power of the QuantStudio 12K Flex Real-time PCR System with qualified TaqMan genotyping assays, this solution delivers a sample-to-answer workflow that allows you to introduce pharmacogenomic testing into your laboratory with ease.

Pharmacogenomics literature

Pharmacogenomics literature

White paper
Infographic
Blog
Article

Resources

Resources

 User Guide
 Flyer

 


Thermo Fisher Scientific PCR PGx solutions: Features and benefits
 

Features include:

  • Fully qualified content—all TaqMan SNP Genotyping Assays have been tested against genomic DNA and synthetic controls
  • Express Panels include our most popular PGx content including—CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A5, SLCO1B1, VKORC1, COMT, OPRM1, DRD2, FII, FV, MTHFR, APOE2, APOE4
  • Flexible formats—our PGx solution has been optimized for anything from custom content to fit your needs, to off-the shelf content
  • Extensive menu of targets—over 2,700 TaqMan SNP Genotyping Assays available, targeting the most common drug metabolizing enzyme (DME) markers (including CYP2D6, CYP2C9, CYP4F2, and more)
  • Calling and reporting solutions—TaqMan Genotyper Software and AlleleTyper Software are available* to quickly and easily determine haplotypes of samples using star-allele nomenclature
  • Utilizing familiar instruments—our PGx solutions can be run on either QuantStudio 5 or QuantStudio 7 for custom plates, and QuantStudio 12K Flex System for OpenArray

*Additional PGx data and support files at bottom of page

 TaqMan OpenArray (OA)TaqMan Array Plates (TAP)
Focus

For mid-higher throughput applications

For low-mid throughput applications

Targets

TaqMan OpenArray PGx Express – 60:

  • 48 samples/plate
  • 60 pre-selected TaqMan PGx Assays

32 assays x 12 samples: 80 plates

64 assays x 6 samples: 160 plates

128 assays x 3 samples: 320 plates

Goals/needs
  • Customers who need between 48–120 markers
  • Genotyping of DME
  • Customers who need between 12–60 markers
  • Seamless, streamlined genotyping and Copy Number Variation (CNV) in single workflow
  • Less waste
Format

Off-the-Shelf and Custom

2,880 reactions with pre-spotted assays

4-hour workflow

Off-the-Shelf and Custom

384-well plates with pre-spotted assays

PGx Express (60) on 384-well plates

3-hour workflow

Compatible instrumentsQuantStudio 12K Flex Real-Time PCR System with OpenArray block

QuantStudio 12K Flex with 384-well block

QuantStudio 7 Flex & 7 Pro with 384-well block

QuantStudio 6 Flex & 6 Pro with 384-well block

QuantStudio 5 with 384-well block

Product

Unit Size

Catalog Number

Ordering information

TaqMan™ OpenArray™ Genotyping Master Mix

1 kit

4404846

Click to view

TaqMan™ Genotyping Master Mix

Sizes vary

Multiple SKUs

Click to view

TaqPath™ ProAmp™ Master Mix

Sizes vary

Multiple SKUs

Click to view


Workflow
 

We offer a simple, efficient workflow designed to maximize results.

Buccal swab, saliva, or blood

Thermo Scientific™ KingFisher™ Flex system with Applied Biosystems™ MagMAX™ DNA Multi-Sample Ultra Kit

Applied Biosystems™ OpenArray™ AccuFill™ System

Applied Biosystems™ QuantStudio™ 12K Flex Real-Time PCR System

Drug metabolism enzyme (DME) assays run on OpenArray plates or 384-well plates

Genotyping data: In-house laboratory information systems (LIS) or relative quantification application

Buccal swab, saliva, or blood

Thermo Scientific™ KingFisher™ Flex system with Applied Biosystems™ MagMAX™ DNA Multi-Sample Ultra Kit

Applied Biosystems™ OpenArray™ AccuFill™ System

Applied Biosystems™ QuantStudio™ 12K Flex Real-Time PCR System

Drug metabolism enzyme (DME) assays run on OpenArray plates or 384-well plates

Genotyping data: In-house laboratory information systems (LIS) or relative quantification application

Resources
 

For Research Use Only. Not for use in diagnostic procedures.

Style Sheet for Global Design System
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