One Lambda MagSort isolates specific HLA Antibodies using magnetic bead panels to adsorb and elute targeted antibodies.

One Lambda™ MagSort™ addresses emerging interests and challenges in adsorption and elution techniques for HLA antibody testing. Targeting individual HLA antigens enables a more focused dataset, to explore and define complex HLA antibody profiles at the antigen-specific level. This novel technology streamlines the process, reducing hands-on time for the laboratory staff, and standardizes a unique isolation approach compared to more cumbersome cell-based approaches.


Capabilities

Targeted technology

  • Individual antigen-coated magnetic beads
  • Elute antibodies that bind to a specific antigen
  • Results in a more focused HLA antibody assessment 

Customizable panels  

  • 59 antigens across 6 locus specific kits
  • Flexibility to focus only on antigens of interest
  • Coverage across well-documented antigens

Efficient workflow 

  • Up to 45 minutes of hands-on time and as little as 4 hours to      workflow completion
  • Uses equipment already found in most laboratories
  • Immediate antigen availability.

How does it work?

MagSort Workflow
MagSort example of results before and after isolating A*02:01

Products & coverage

MagSort Class I HLA-A

MagSort Class I HLA-B

MagSort Class I HLA-C

MagSort Class II HLA-DRB1  MagSort Class II HLA-DQ MagSort Class II HLA-DP

A*01:01

B*07:02

C*01:02

DRB1*01:01 DQB1*02:01
DQA1*02:01
DPB1*01:01
DPA1*01:03

A*02:01

B*08:01

C*02:02

DRB1*03:01

DQB1*02:02
DQA1*02:01
DPB1*02:01
DPA1*01:03

A*03:01

B*13:01

C*03:03

DRB1*04:01

DQB1*03:01
DQA1*02:01
DPB1*03:01
DPA1*01:03

A*11:01

B*15:01

C*03:04

DRB1*04:04

DQB1*03:02
DQA1*02:01
DPB1*04:01
DPA1*01:03

A*24:02

B*44:02

C*04:01

DRB1*07:01

DQB1*03:03
DQA1*02:01
DPB1*04;02
DPA1*01:03

A*25:01

B*46:01

C*05:01

DRB1*08:01

DQB1*04:01
DQA1*02:01
DPB1*11:01
DPA1*01:03
A*29:01 B*53:01 C*07:02 DRB1*11:01 DQB1*05:01
DQA1*01:01
DPB1*17:01
DPA1*02:01
A*30:01 B*57:01 C*12:03 DRB1*12:01 DQB1*06:02
DQA1*01:01
DPB1*19:01
DPA1*01:03
A*33:03 B*67:01 C*15:02 DRB1*13:01 DQB1*06:03
DQA1*01:03
 
A*68:01 B*73:01 C*16:01 DRB1*15:01    
    C*17:01 DRB1*16:01    

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