Whether you are new to cryo-electron microscopy (cryo-EM) or have years of experience with this technology, securing funding can be demanding, time-consuming, and stressful. Our team is here to help! This funding support center contains several resources including:

  • Proposal writing tools
  • Technical content, data sheets, guides

Some common funding challenges include:

  • Identifying the right grant and determining eligibility
  • Finding the right collaborators
  • Getting preliminary data in time for submission; setting up demos with vendors
  • Writing and story telling
  • Obtaining short and long-term institutional support
  • Acquiring a copy of a similar, successful proposal
  • Managing time

Our technical experts can support you every step of the way:

  • Helping you gather the right information to submit a well-supported and accurate application
  • Getting the preliminary data and rationale for your proposal
  • Providing information about financing and leasing solutions
  • Discussing ideal workflow solutions for your analytical needs
  • And much more

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Getting started with cryo-EM

Cryo-EM is accessible to a broader range of scientists, including first-time users in the fields of biochemistry, molecular biology, structural biology, cell biology, and more.  Cryo-EM is being used to understand protein structures in challenging samples, such as membrane proteins, dynamic proteins, and large membrane complexes. Thermo Fisher Scientific offers a range of instruments to get any user started in room temperature and cryo-EM. 

Our dedicated customer success managers are your scientific partners, providing laboratory organization support, from sample preparation to electron microscopy and IT infrastructure. Explore our guidance for planning a cryo-EM laboratory for more information.

 VitrobotTalos L120C TEMTalos F200C TEMTundra Cryo-TEMGlacios Cryo-TEMKrios G4 Cryo-TEMAquilos 2 Cryo-FIB
 
Vitrobot System
Talos L120C TEM
Talos F200C TEM
Tundra Cryo-TEM
Glacios Cryo-TEM
Krios G4 Cryo-TEM
Aquilos 2 Cryo-FIB
Ideal Use or Applications
  • Sample prep
  • Vitrification
  • Room temperature EM
  • Pathology
  • Cell biology
  • Negative staining
  • Limited Cryo-EM screening
  • Room temperature EM
  • Pathology
  • Cell biology
  • Negative staining
  • Limited cryo-EM screening
  • Limited tomography
  • Sample optimization
  • Biochemistry optimization
  • Structure determination
  • 100 kV single particle analysis (SPA)
  • Structure determination
  • 200 kV SPA
  • Cryo-tomography
  • MicroED
  • Energy filter compatible
  • Structure determination 
  • 300KV SPA
  • Cryo-tomography
  • MicroED
  • Energy filter compatible
  • Highest resolution 
  • Cryo-FIB (Cryo-Focused Ion Beam) milling
  • Lamella prep for cryo-tomography
  • Targeted FIB milling
Key Benefits

Sample vitrification for optimal cryo-EM analysis

Ease-of-use, with multi-functional flexible applications

Ease-of-use, with multi-functional flexible applications

Cryo-EM within your reach: ease of use, with AI-guided automation

Routine, high- resolution SPA, with high throughput and productivity

Highest resolution SPA and tomography, with highest throughput and productivity

Dedicated cryo-milling for quality preparation of lamellas, with automation for ease of generation

User Experience Level

All users

New users to experts

New users to experts

New to moderately experienced users

Moderately experienced to experts

Moderately experienced to experts

Moderately experienced to experts

Cost to Get Started 

$

$$

$

$$

$$$

 
Price Per Structure 

N/A

N/A

$$$

$$

$

 
Product DatasheetsVitrobotTalos L120CTalos F200CTundra Cryo-TEMGlacios Cryo-TEMKrios G4 Cryo-TEM
Krios Rx Cryo-TEM
Aquilos 2 Cryo-FIB

 


Funding resource center

Accessing the latest cryo-EM technology is easier than ever. Learn more about our financing solutions and explore our proposal writing tools below. Let one of our experts find a solution for your needs today.

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funding-infographic-half-page-580x360

What does Thermo Fisher Financial Services (TFFS) do?

Thermo Fisher Financial Services helps you get the instrumentation and services your lab needs to achieve its research goals through a variety of funding paths that can be customized to meet your requirements.

How can you use Thermo Fisher Financial Services to fund your cryo-EM facility?

Thermo Fisher Financial Services provide various options for funding systems and services that can be used alone or in combination with internal and external funds and grants. This includes the flexible Bridge to Grant (B2G) program, which allows you to use a cryo-EM system while you wait for your grant notification in accordance with NIH guidelines.

What are our options?

  • B2G program lets you achieve your cryo-EM goals while waiting for your grant to be awarded
  • Competitive and flexible financing
  • Leasing and lease-to-own options

Contact one of our specialists today to learn more about financing solutions and leasing packages!

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Featured Thermo Fisher Financial Services Resources

Whether you are new to grant writing or have years of experience, securing funding can be demanding, time-consuming, and stressful. Not all funding opportunities are created equal, but successful grant applications have much in common.

Watch this on-demand webinar given by Dr. Christopher Dant to learn about proven strategies used in the well-known Research (R01) grant application that can support your application for the NIH High-End Instrumentation (HEI) Grant Program (S10).

In this webinar you will learn:

  • The purpose and boundaries of the NIH S10 High-End Instrumentation and Shared Instrumentation Grant Programs and how to interpret the NIH Program Announcement
  • Specifics of application requirements, including what goes in these grants and what does not
  • Proven strategies for writing a successful S10 grant

Interested in more supplemental information? Check out our whitepaper.


Cryo-EM Resources


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