Research equipment grants

Cryo-electron microscope grant writing and technical resources

Whether you are new to cryo-electron microscopy (cryo-EM) or have years of experience with this technology, securing funding can be demanding, time-consuming, and stressful. Our team is here to help! This funding support center contains several resources including:

  • Proposal writing tools
  • Technical content, data sheets, guides

Some common funding challenges include:

  • Identifying the right grant and determining eligibility
  • Finding the right collaborators
  • Getting preliminary data in time for submission; setting up demos with vendors
  • Writing and story telling
  • Obtaining short and long-term institutional support
  • Acquiring a copy of a similar, successful proposal
  • Managing time

Our technical experts can support you every step of the way:

  • Helping you gather the right information to submit a well-supported and accurate application
  • Getting the preliminary data and rationale for your proposal
  • Providing information about financing and leasing solutions
  • Discussing ideal workflow solutions for your analytical needs
  • And much more

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Getting started with cryo-EM

Cryo-EM is accessible to a broader range of scientists, including first-time users in the fields of biochemistry, molecular biology, structural biology, cell biology, and more.  Cryo-EM is being used to understand protein structures in challenging samples, such as membrane proteins, dynamic proteins, and large membrane complexes. Thermo Fisher Scientific offers a range of instruments to get any user started in room temperature and cryo-EM. 

Cryo-electron microscopy equipment

Cryo-EM sample preparation and testing instruments from Thermo Fisher Scientific

Our dedicated customer success managers are your scientific partners, providing laboratory organization support, from sample preparation to electron microscopy and IT infrastructure. Explore our guidance for planning a cryo-EM laboratory for more information.

 VitrobotTalos L120C TEMTalos F200C TEMTundra Cryo-TEMGlacios Cryo-TEMKrios G4 Cryo-TEMAquilos 2 Cryo-FIB
 
Vitrobot System
Talos L120C TEM
Talos F200C TEM
Tundra Cryo-TEM
Glacios Cryo-TEM
Krios G4 Cryo-TEM
Aquilos 2 Cryo-FIB
Ideal Use or Applications
  • Sample prep
  • Vitrification
  • Room temperature EM
  • Pathology
  • Cell biology
  • Negative staining
  • Limited Cryo-EM screening
  • Room temperature EM
  • Pathology
  • Cell biology
  • Negative staining
  • Limited cryo-EM screening
  • Limited tomography
  • Sample optimization
  • Biochemistry optimization
  • Structure determination
  • 100 kV single particle analysis (SPA)
  • Structure determination
  • 200 kV SPA
  • Cryo-tomography
  • MicroED
  • Energy filter compatible
  • Structure determination 
  • 300KV SPA
  • Cryo-tomography
  • MicroED
  • Energy filter compatible
  • Highest resolution 
  • Cryo-FIB (Cryo-Focused Ion Beam) milling
  • Lamella prep for cryo-tomography
  • Targeted FIB milling
Key Benefits

Sample vitrification for optimal cryo-EM analysis

Ease-of-use, with multi-functional flexible applications

Ease-of-use, with multi-functional flexible applications

Cryo-EM within your reach: ease of use, with AI-guided automation

Routine, high- resolution SPA, with high throughput and productivity

Highest resolution SPA and tomography, with highest throughput and productivity

Dedicated cryo-milling for quality preparation of lamellas, with automation for ease of generation

User Experience Level

All users

New users to experts

New users to experts

New to moderately experienced users

Moderately experienced to experts

Moderately experienced to experts

Moderately experienced to experts

Cost to Get Started 

$

$$

$

$$

$$$

 
Price Per Structure 

N/A

N/A

$$$

$$

$

 
Product DatasheetsVitrobotTalos L120CTalos F200CTundra Cryo-TEMGlacios Cryo-TEMKrios G4 Cryo-TEM
Aquilos 2 Cryo-FIB

Cryo-EM grant proposal and funding resource center

Accessing the latest cryo-EM technology is easier than ever. Learn more about our financing solutions and explore our proposal writing tools below. Let one of our experts find a solution for your needs today.

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  • Funding Opportunities
  • Application timeline
  • Potential funding opportunities
Cryo-EM grant proposal and funding resource center

What does Thermo Fisher Financial Services (TFFS) do?

Thermo Fisher Financial Services helps you get the instrumentation and services your lab needs to achieve its research goals through a variety of funding paths that can be customized to meet your requirements.

How can you use Thermo Fisher Financial Services to fund your cryo-EM facility?

Thermo Fisher Financial Services provide various options for funding systems and services that can be used alone or in combination with internal and external funds and grants. This includes the flexible Bridge to Grant (B2G) program, which allows you to use a cryo-EM system while you wait for your grant notification in accordance with NIH guidelines.

Financial-services-500x500

What are our options?

  • B2G program lets you achieve your cryo-EM goals while waiting for your grant to be awarded
  • Competitive and flexible financing
  • Leasing and lease-to-own options

Contact one of our specialists today to learn more about financing solutions and leasing packages!

Example timeline

Featured Thermo Fisher Financial Services Resources

Proposal Writing Tools

Whether you are new to grant writing or have years of experience, securing funding can be demanding, time-consuming, and stressful. Not all funding opportunities are created equal, but successful grant applications have much in common.

Watch this on-demand webinar given by Dr. Christopher Dant to learn about proven strategies used in the well-known Research (R01) grant application that can support your application for the NIH High-End Instrumentation (HEI) Grant Program (S10).

In this webinar you will learn:

  • The purpose and boundaries of the NIH S10 High-End Instrumentation and Shared Instrumentation Grant Programs and how to interpret the NIH Program Announcement
  • Specifics of application requirements, including what goes in these grants and what does not
  • Proven strategies for writing a successful S10 grant

Public and private grants are an ideal way to seek funding for the latest in cryo-EM technology. This table presents some of the typical and lesser-known sources of funding.

DateGrant NameDivisionRange
Proposals Accepted Anytime   
RollingInfrastructure Innovation for Biological Research (Innovation)NSF20 to 40 Awards in a pool of $18 - $20M*
January   
7- Jan (Preliminary) 23-April (Full Proposal by invitation only)Mid-scale Research Infrastructure-1 (Mid-scale RI-1)NSF$6M - $20M
19-JanMajor Research Instrumentation Program: (MRI) - Track 1NSF$100K - $1M
19-JanMajor Research Instrumentation Program: (MRI) - Track 2NSF$1M - $4M
25-JanNational Centers for Biomedical Imaging and BioengineeringNIH$500K - $750K
February   
3- Feb (Letter of Intent) 5- March (Preliminary) 20- Sept (Full Proposal)Mid-scale Research Infrastructure-2 (Mid-scale RI-2)NSF$20M - $100M
2-26 (Eligibility Determination) 6-11 (Full Proposal)ARNOLD AND MABEL BECKMAN FOUNDATION INSTRUMENTATION GRANTPrivate<$1.5M
May   
25-MayNational Centers for Biomedical Imaging and BioengineeringNIH$500K - $750K
14-MayDefense University Research Instrumentation Program (DURIP)DoD$50K - $1.5M
31-MayThe Guenther Foundation - California onlyPrivateOpen
June   
15-JunS10 - Shared Instrumentation Grant (SIG) ProgramNIH$50K - $600K
15-JunS10 - High-End Instrumentation (HEI) Grant ProgramNIH$601K - $2M
August   
20-AugHoward Hughes Medical InstitutePrivate 
September   
7-SepNational Centers for Biomedical Imaging and BioengineeringNIH$500K - $750K

Thermo Fisher does not guarantee (i) the accuracy or completeness of any information related to grants or funding resources or (ii) that you will receive any grant or secure any funding regardless of any assistance Thermo Fisher provides.

Interested in more supplemental information?

 

Watch an on-demand Q&A session about grant writing featuring Dr. Christopher Dant and Thermo Fisher experts.

grant-writing-journey-v2-580x300

Cryo-EM Resources

 

Ask the Experts

Ask the Experts is our monthly series that focuses on various electron microscopy topics with an interactive discussion.

Ask the Experts | Strategies for Successful Grant Writing

Hear from Dr. Christopher Dant from Medcom Consulting as he discusses proven strategies for writing successful S10 grants. In this session, you’ll also learn about resources and grant writing support offered by Thermo Fisher Scientific experts, who are there for you and your lab every step of the way.

Writing the NIH Shared Instrumentation Grant (S10): Strategies for Success

Learn about proven strategies used in the well-known Research (R01) grant application that can support your application for the NIH High-End Instrumentation (HEI) Grant Program (S10).

Tundra Cryo-TEM Virtual Launch Event

Watch the event replay to learn about how our new, easy-to-use instrument is transforming structural biology research.

 

e-Learning

 

Electron Microscopy Learning Center ›
  • Browse expert interviews, webinars, eBooks, educational resources and more.
     
EM-learning.com ›
  • Access over 70 hours of lectures and videos on cryo-electron microscopy.

 

Publications library


Publications search tool ›
  • Search and find scientific papers relevant to your research.
     
Subscribe to the Monthly Publications Newsletter ›

 

Ask the Experts

Ask the Experts is our monthly series that focuses on various electron microscopy topics with an interactive discussion.

Ask the Experts | Strategies for Successful Grant Writing

Hear from Dr. Christopher Dant from Medcom Consulting as he discusses proven strategies for writing successful S10 grants. In this session, you’ll also learn about resources and grant writing support offered by Thermo Fisher Scientific experts, who are there for you and your lab every step of the way.

Writing the NIH Shared Instrumentation Grant (S10): Strategies for Success

Learn about proven strategies used in the well-known Research (R01) grant application that can support your application for the NIH High-End Instrumentation (HEI) Grant Program (S10).

Tundra Cryo-TEM Virtual Launch Event

Watch the event replay to learn about how our new, easy-to-use instrument is transforming structural biology research.

 

e-Learning

 

Electron Microscopy Learning Center ›
  • Browse expert interviews, webinars, eBooks, educational resources and more.
     
EM-learning.com ›
  • Access over 70 hours of lectures and videos on cryo-electron microscopy.

 

Publications library


Publications search tool ›
  • Search and find scientific papers relevant to your research.
     
Subscribe to the Monthly Publications Newsletter ›


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